{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T05:05:46Z","timestamp":1784783146488,"version":"3.55.0"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T00:00:00Z","timestamp":1639353600000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Parsonage\u2013Turner syndrome is an acute peripheral neuropathy that affects the upper brachial plexus region. Previously published reports demonstrate that the condition can be triggered by surgery, infection, autoimmune diseases, strenuous exercise, trauma, radiation, and vaccination. Parsonage\u2013Turner syndrome has already been reported in three other patients who were vaccinated against coronavirus disease 2019.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We report the case of a 51-year-old Caucasian man without comorbidities who received the first dose of the ChAdOx1-S recombinant vaccine (Vaxzevria, AstraZeneca, Oxford, UK) against coronavirus disease 2019 and was diagnosed with Parsonage\u2013Turner syndrome. A few days after getting vaccinated, the patient reported a progressive increase in pain in the region of vaccine administration. One month later, the shoulder pain was followed by symptoms of hypoesthesia and muscle weakness on abduction and elevation of the left upper limb. Neurological examination revealed an atrophy of the proximal muscles of the left upper limb, accompanied by paresis of the left deltoid, biceps brachii, triceps brachii, and infraspinatus muscles. Electroneuromyography carried out 3\u00a0months after the onset of symptoms showed signs consistent with brachial plexus neuritis. The adverse reaction has been properly reported to the Italian Pharmacovigilance System (Italian Medicines Agency\u2014<jats:italic>Agenzia Italiana del Farmaco<\/jats:italic>.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The increased awareness of such association is essential for early identification and diagnosis and, thus, better clinical outcomes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-03176-8","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T13:03:10Z","timestamp":1639400590000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Parsonage\u2013Turner syndrome following coronavirus disease 2019 immunization with ChAdOx1-S vaccine:\u00a0a case report and review of the\u00a0literature"],"prefix":"10.1186","volume":"15","author":[{"given":"Bruno Kusznir","family":"Vitturi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Grandis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Beltramini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Orsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Schenone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo","family":"Icardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Durando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,13]]},"reference":[{"issue":"6","key":"3176_CR1","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1002\/mus.25422","volume":"55","author":"MA Ferrante","year":"2017","unstructured":"Ferrante MA, Wilbourn AJ. Lesion distribution among 281 patients with sporadic neuralgic amyotrophy. Muscle Nerve. 2017;55(6):858\u201361. https:\/\/doi.org\/10.1002\/mus.25422.","journal-title":"Muscle Nerve"},{"issue":"6","key":"3176_CR2","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1038\/nrneurol.2011.62","volume":"7","author":"N van Alfen","year":"2011","unstructured":"van Alfen N. Clinical and pathophysiological concepts of neuralgic amyotrophy. Nat Rev Neurol. 2011;7(6):315\u201322. https:\/\/doi.org\/10.1038\/nrneurol.2011.62.","journal-title":"Nat Rev Neurol"},{"key":"3176_CR3","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.clinimag.2020.11.017","volume":"72","author":"MA Mitry","year":"2021","unstructured":"Mitry MA, Collins LK, Kazam JJ, Kaicker S, Kovanlikaya A. Parsonage-Turner syndrome associated with SARS-CoV2 (COVID-19) infection. Clin Imaging. 2021;72:8\u201310. https:\/\/doi.org\/10.1016\/j.clinimag.2020.11.017.","journal-title":"Clin Imaging"},{"issue":"3","key":"3176_CR4","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-237459","volume":"14","author":"C Young Han","year":"2021","unstructured":"Young Han C, Tarr AM, Gewirtz AN, Kaunzner UW, Roy-Burman P, Cutler TS, MacGowan DJ. Brachial plexopathy as a complication of COVID-19. BMJ Case Rep. 2021;14(3): e237459. https:\/\/doi.org\/10.1136\/bcr-2020-237459.","journal-title":"BMJ Case Rep"},{"issue":"3","key":"3176_CR5","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1002\/mus.20108","volume":"30","author":"L Zhou","year":"2004","unstructured":"Zhou L, Yousem DM, Chaudhry V. Role of magnetic resonance neurography in brachial plexus lesions. Muscle Nerve. 2004;30(3):305\u20139. https:\/\/doi.org\/10.1002\/mus.20108.","journal-title":"Muscle Nerve"},{"key":"3176_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrleng.2021.05.002","author":"JA Crespo Burillo","year":"2021","unstructured":"Crespo Burillo JA, Loriente Mart\u00ednez C, Garc\u00eda Arguedas C, Mora Pueyo FJ. Amyotrophic neuralgia secondary to Vaxzevri (AstraZeneca) COVID-19 vaccine. Neurologia. 2021. https:\/\/doi.org\/10.1016\/j.nrleng.2021.05.002.","journal-title":"Neurologia"},{"key":"3176_CR7","doi-asserted-by":"publisher","DOI":"10.1002\/pmrj.12619","author":"N Diaz-Segarra","year":"2021","unstructured":"Diaz-Segarra N, Edmond A, Gilbert C, Mckay O, Kloepping C, Yonclas P. Painless idiopathic neuralgic amyotrophy after COVID19 vaccination: a case report. PM&R. 2021. https:\/\/doi.org\/10.1002\/pmrj.12619.","journal-title":"PM&R"},{"issue":"1","key":"3176_CR8","doi-asserted-by":"publisher","first-page":"E3","DOI":"10.1002\/mus.27255","volume":"64","author":"S Mahajan","year":"2021","unstructured":"Mahajan S, Zhang F, Mahajan A, Zimnowodzki S. Parsonage Turner syndrome after COVID-19 vaccination. Muscle Nerve. 2021;64(1):E3\u20134. https:\/\/doi.org\/10.1002\/mus.27255.","journal-title":"Muscle Nerve"},{"issue":"3","key":"3176_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006976.pub2","volume":"2009","author":"N van Alfen","year":"2009","unstructured":"van Alfen N, van Engelen BG, Hughes RA. Treatment for idiopathic and hereditary neuralgic amyotrophy (brachial neuritis). Cochrane Database Syst Rev. 2009;2009(3): CD006976. https:\/\/doi.org\/10.1002\/14651858.CD006976.pub2.","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03176-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-021-03176-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03176-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T13:05:04Z","timestamp":1639400704000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-021-03176-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["3176"],"URL":"https:\/\/doi.org\/10.1186\/s13256-021-03176-8","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"25 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"589"}}