{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T08:03:15Z","timestamp":1648972995979},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Aortic regurgitation is attributed to congenital and acquired abnormalities of the aortic valve or aortic valve supporting structures. The most common cause of aortic regurgitation is atherosclerotic degeneration of the valve, especially in the presence of a bicuspid aortic valve.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case summary<\/jats:title>\n                <jats:p>A 25-year-old Persian man with no past medical history, developed dyspnea since 1\u00a0week before his first visit to the physician. He was an active person up to this time, and had no history of trauma or chest pain. Transthoracic echocardiography showed severe aortic regurgitation in the context of flail bicuspid aortic valve, with no evidence of endocarditis. Laboratory tests including blood cultures were negative for infection. The patient underwent aortic valve replacement and the diagnosis was confirmed at time of surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This case represents noninfective and nontraumatic spontaneous flail of bicuspid aortic valve.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-03211-8","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:02:48Z","timestamp":1640649768000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A heart in a heart: a case report of spontaneous flail of bicuspid aortic valve"],"prefix":"10.1186","volume":"15","author":[{"given":"Khadije","family":"Mohammadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahsa","family":"Akrami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzieh","family":"Mirtajaddini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,12,28]]},"reference":[{"key":"3211_CR1","unstructured":"Paras I, Khan MA, Sher-i-Murtaza M, Hamid W, Raheel HMA, Gilani R. 31.8. 34 Evaluation of left ventricular size in early postoperative period in patients with aortic regurgitation after aortic valve replacement Iftikhar Paras1, Muhammad Ali Khan1, Muhammad."},{"issue":"1","key":"3211_CR2","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1378\/chest.78.1.116","volume":"78","author":"M Alam","year":"1980","unstructured":"Alam M, Goldstein S. Echocardiographic features of flail aortic porcine valve. Chest. 1980;78(1):116\u20137.","journal-title":"Chest"},{"key":"3211_CR3","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/196037","author":"I Mordi","year":"2012","unstructured":"Mordi I, Tzemos N. Bicuspid aortic valve disease: a comprehensive review. Cardiol Res Pract. 2012. https:\/\/doi.org\/10.1155\/2012\/196037.","journal-title":"Cardiol Res Pract"},{"issue":"1","key":"3211_CR4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/S0894-7317(99)70176-8","volume":"12","author":"TC Yeo","year":"1999","unstructured":"Yeo TC, Ling LH, Ng WL, Chia BL. Spontaneous aortic laceration causing flail aortic valve and acute aortic regurgitation. 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Eur J Case Rep Intern Med. 2021;8(2):002234.","journal-title":"Eur J Case Rep Intern Med."},{"issue":"5","key":"3211_CR9","doi-asserted-by":"publisher","first-page":"e083","DOI":"10.1097\/j.pbj.0000000000000083","volume":"5","author":"C Zhu","year":"2020","unstructured":"Zhu C, Torres SC, Nunes JPL. Aortic valve fenestrations: a review. Porto Biomed J. 2020;5(5):e083.","journal-title":"Porto Biomed J."},{"issue":"4","key":"3211_CR10","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/S1054-8807(99)00009-5","volume":"8","author":"H Blaszyk","year":"1999","unstructured":"Blaszyk H, Witkiewicz AK, Edwards WD. Acute aortic regurgitation due to spontaneous rupture of a fenestrated cusp: report in a 65-year-old man and review of seven additional cases. 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Anatol J Cardiol. 2017;17(6):E5.","journal-title":"Anatol J Cardiol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03211-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-021-03211-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03211-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:02:55Z","timestamp":1640649775000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-021-03211-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["3211"],"URL":"https:\/\/doi.org\/10.1186\/s13256-021-03211-8","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"10 September 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 December 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"614"}}