{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:38:38Z","timestamp":1791229118249,"version":"4.1.0"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T00:00:00Z","timestamp":1640304000000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Facial onset sensory and motor neuropathy is a very rare sensorimotor disorder characterized by facial onset and gradual progression, with approximately 100 cases reported worldwide in 2020. We report on our experience with a facial onset sensory and motor neuropathy case in our outpatient pain clinic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 71-year-old Japanese man with a previous diagnosis of trigeminal nerve palsy complained of facial paresthesia, cervical pain, and arm numbness. Cervical facet arthropathy was diagnosed initially, but neither pharmacotherapy nor nerve blocking alleviated his symptoms. We suspected bulbar palsy based on the presence of tongue fasciculation, which prompted referral to a neurologist. Based on a series of neurological examinations, facial onset sensory and motor neuropathy was ultimately diagnosed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pain clinicians must be mindful of rare diseases such as facial onset sensory and motor neuropathy; if they are unable to make a diagnosis, they should consult with other competent specialists.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s13256-021-03212-7","type":"journal-article","created":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T00:05:56Z","timestamp":1640304356000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Facial onset sensory and motor neuropathy in a pain clinic outpatient: a case report"],"prefix":"10.1186","volume":"15","author":[{"given":"Hiroki","family":"Hanawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Nagaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuya","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuya","family":"Akutsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teppei","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5872-4421","authenticated-orcid":false,"given":"Shinsuke","family":"Hamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,24]]},"reference":[{"issue":"2","key":"3212_CR1","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1212\/CPJ.0000000000000834","volume":"11","author":"EMJ de Boer","year":"2021","unstructured":"de Boer EMJ, Barritt AW, Elamin M, Anderson SJ, Broad R, Nisbet A, et\u00a0al. Facial onset sensory and motor neuronopathy: new cases, cognitive changes, and pathophysiology. Neurol Clin Pract. 2021;11(2):147\u201357. https:\/\/doi.org\/10.1212\/CPJ.0000000000000834.","journal-title":"Neurol Clin Pract."},{"key":"3212_CR2","doi-asserted-by":"publisher","first-page":"3384","DOI":"10.1093\/brain\/awl258","volume":"129","author":"S Vucic","year":"2006","unstructured":"Vucic S, Tian D, Chong PST, Cudkowicz ME, Hedley-Whyte ET, Cros D. Facial onset sensory and motor neuronopathy (FOSMN syndrome): a novel syndrome in neurology. Brain. 2006;129:3384\u201390. https:\/\/doi.org\/10.1093\/brain\/awl258.","journal-title":"Brain"},{"key":"3212_CR3","doi-asserted-by":"crossref","first-page":"e951","DOI":"10.1212\/WNL.0000000000007008","volume":"92","author":"AM Rossor","year":"2019","unstructured":"Rossor AM, Jaunmuktane Z, Rossor MN, Hoti G, Reilly MM. TDP43 pathology in the brain, spinal cord, and dorsal root ganglia of a patient with FOSMN. Neurology. 2019;92:e951\u20136.","journal-title":"Neurology"},{"issue":"12","key":"3212_CR4","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1007\/s10072-016-2686-7","volume":"37","author":"Q Zheng","year":"2016","unstructured":"Zheng Q, Chu L, Tan L, Zhang H. Facial onset sensory and motor neuronopathy. Neurol Sci. 2016;37(12):1905\u20139. https:\/\/doi.org\/10.1007\/s10072-016-2686-7.","journal-title":"Neurol Sci"},{"key":"3212_CR5","doi-asserted-by":"publisher","DOI":"10.5603\/PJNNS.a2021.0018","author":"M Grudzi\u0144ska","year":"2021","unstructured":"Grudzi\u0144ska M, Kierdaszuk B, Lipowska M, Rosiak E, Kostera-Pruszczyk A. Facial onset sensory and motor neuronopathy syndrome: a rare variant of motor neurone disease. Neurol Neurochir Pol. 2021. https:\/\/doi.org\/10.5603\/PJNNS.a2021.0018.","journal-title":"Neurol Neurochir Pol"},{"key":"3212_CR6","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1136\/jnnp.2009.194019","volume":"82","author":"M de Carvalho","year":"2011","unstructured":"de Carvalho M, Swash M. Fasciculation-cramp syndrome preceding anterior horn cell disease: an intermediate syndrome? J Neurol Neurosurg Psychiatry. 2011;82:459\u201361. https:\/\/doi.org\/10.1136\/jnnp.2009.194019.","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03212-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-021-03212-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03212-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T20:43:07Z","timestamp":1699994587000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-021-03212-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["3212"],"URL":"https:\/\/doi.org\/10.1186\/s13256-021-03212-7","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"29 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"In our hospital, the publication of case reports is exempt from ethics committee approval.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"609"}}