{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:17:50Z","timestamp":1784132270402,"version":"3.55.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T00:00:00Z","timestamp":1642204800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T00:00:00Z","timestamp":1642204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Fenestration of the cervical segment of the\u00a0internal carotid artery is a very rare finding, and its origin is still not fully understood. Explanations of its genesis range from dissections leading to the fenestration to the more common interpretation as a developmental vascular variant. However, most reported cases were symptomatic and presented with dissections, where even endovascular treatment of the fenestration of the cervical segment of the internal carotid artery became necessary. Here we report a case of a fenestration of the cervical segment of the internal carotid artery suffering a transitory ischemic attack and local pain in absence of any sign of dissection.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 62-year-old Caucasian male patient was admitted to our institution because of an episode of amaurosis fugax, initially accompanied with headache. Magnetic resonance imaging revealed an intact fenestration of the cervical segment of the internal carotid artery on the symptomatic side. With antiplatelet therapy, all symptoms vanished within 2\u00a0months of the initial event.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Our findings support the interpretation of a fenestration of the cervical segment of the internal carotid artery as a developmental vascular variant, but also suggest a substantial risk for dissection and ischemic stroke. Even in case of an accidental finding, clinicians should be aware of this. At least in this case, antiplatelet therapy seemed beneficial.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-021-03227-0","type":"journal-article","created":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T00:05:39Z","timestamp":1642205139000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Transitory ischemic attack associated with a rare fenestration of the cervical segment of the internal carotid artery: a case report"],"prefix":"10.1186","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1418-7924","authenticated-orcid":false,"given":"Christian","family":"Nasel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelina","family":"Poetsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia","family":"Brunner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewald","family":"Moser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,15]]},"reference":[{"key":"3227_CR1","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/0090-3019(85)90214-9","volume":"23","author":"T Hasegawa","year":"1985","unstructured":"Hasegawa T, Kashihara K, Ito H, Yamamoto S. Fenestration of the internal carotid artery. Surg Neurol. 1985;23:391\u20135.","journal-title":"Surg Neurol"},{"key":"3227_CR2","doi-asserted-by":"publisher","first-page":"306","DOI":"10.2176\/nmc.33.306","volume":"33","author":"H Nakamura","year":"1993","unstructured":"Nakamura H, Yamada H, Nagao T, Fujita K, Tamaki N. Fenestration of the internal carotid artery associated with an ischemic attack\u2013case report. Neurol Med Chir (Tokyo). 1993;33:306\u20138.","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"3227_CR3","first-page":"421","volume":"25","author":"P Gailloud","year":"2004","unstructured":"Gailloud P, Carpenter J, Heck DV, Murphy KJ. Pseudofenestration of the cervical internal carotid artery: a pathologic process that simulates an anatomic variant. AJNR Am J Neuroradiol. 2004;25:421\u20134.","journal-title":"AJNR Am J Neuroradiol"},{"key":"3227_CR4","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.jvs.2020.03.034","volume":"72","author":"M Zheng","year":"2020","unstructured":"Zheng M, Liu X, Song Y, Zhang J, Han J. Rare fenestration of an occluded internal carotid artery treated with stenting. J Vasc Surg. 2020;72:319\u201320.","journal-title":"J Vasc Surg"},{"key":"3227_CR5","doi-asserted-by":"publisher","first-page":"257","DOI":"10.47162\/RJME.61.1.30","volume":"61","author":"L M\u0103rginean","year":"2020","unstructured":"M\u0103rginean L, Filep RC, Constantin C, B\u0103la\u015fa AF, M\u00fchlfay G. Fenestration of the cervical internal carotid artery misdiagnosed as dissection. Rom J Morphol Embryol. 2020;61:257\u201360.","journal-title":"Rom J Morphol Embryol"},{"key":"3227_CR6","first-page":"908","volume":"16","author":"RA Koenigsberg","year":"1995","unstructured":"Koenigsberg RA, Zito JL, Patel M, Swartz JD, Goldofsky E, et\u00a0al. Fenestration of the internal carotid artery: a rare mass of the hypotympanum associated with persistence of the stapedial artery. AJNR Am J Neuroradiol. 1995;16:908\u201310.","journal-title":"AJNR Am J Neuroradiol"},{"key":"3227_CR7","first-page":"205","volume":"32","author":"DH Padget","year":"1948","unstructured":"Padget DH. The development of the cranial arteries in the human embryo. Contrib Embryol. 1948;32:205\u201361.","journal-title":"Contrib Embryol"},{"key":"3227_CR8","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/BF00342603","volume":"19","author":"FC Killien","year":"1980","unstructured":"Killien FC, Wyler AR, Cromwell LD. Duplication of the internal carotid artery. Neuroradiology. 1980;19:101\u20132.","journal-title":"Neuroradiology"},{"key":"3227_CR9","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1097\/WNR.0000000000001720","volume":"32","author":"D Ye","year":"2021","unstructured":"Ye D, Huang J, Wang S, Sheng S, Liu M. Cerebral arterial fenestration associated with stroke and other cerebrovascular diseases. NeuroReport. 2021;32:1279\u201386.","journal-title":"NeuroReport"},{"key":"3227_CR10","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1148\/radiology.199.1.8633145","volume":"199","author":"C Ozdoba","year":"1996","unstructured":"Ozdoba C, Sturzenegger M, Schroth G. Internal carotid artery dissection: MR imaging features and clinical-radiologic correlation. Radiology. 1996;199:191\u20138.","journal-title":"Radiology"}],"updated-by":[{"DOI":"10.1186\/s13256-022-03341-7","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000}}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03227-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-021-03227-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-021-03227-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T11:07:55Z","timestamp":1646046475000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-021-03227-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,15]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["3227"],"URL":"https:\/\/doi.org\/10.1186\/s13256-021-03227-0","relation":{"correction":[{"id-type":"doi","id":"10.1186\/s13256-022-03341-7","asserted-by":"object"}]},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,15]]},"assertion":[{"value":"20 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 February 2022","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1186\/s13256-022-03341-7","URL":"https:\/\/doi.org\/10.1186\/s13256-022-03341-7","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"For this type of study, formal consent or informed consent were not required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"13"}}