{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:39:04Z","timestamp":1789925944054,"version":"4.0.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T00:00:00Z","timestamp":1647302400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T00:00:00Z","timestamp":1647302400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Pancoast tumors represent a unique subset of lung cancers wherein a\u00a0primary neoplasm arises in the lung\u2019s apex and invades the surrounding soft tissues. One of the main challenges in the diagnosis and treatment of these apical lung cancers is that they are usually not visualized on initial chest x-ray and, by the time the patient presents with symptoms, the tumor has almost always invaded nearby structures.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>Herein we report a case of a 58-year-old nonsmoking African American male who presented to the neurology clinic with a history of multiple chronic joint pains. The patient complained of shoulder pain that traveled into his right arm and right finger and had worsened over the past 9 months. The patient also reported decreased right proximal strength and swelling of his right hand. Magnetic resonance imaging of the shoulder and cervical region showed mild cervical spondylosis and a questionable right apical mass. A subsequent high-resolution computed tomography scan of the chest revealed a large right apical lung mass, with chest wall invasion and erosion of the adjacent ribs. Biopsy of the mass confirmed poorly differentiated non-small cell lung cancer. Radiation therapy was initiated, and the patient\u2019s pain improved significantly. Given the size of the tumor, chemotherapy was recommended by the oncology team. The patient decided against chemotherapy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This case highlights the importance of early diagnosis by expanding the differential diagnosis in patients presenting with weakness, sensory loss, and shoulder pain beyond radiculopathy or joint-related diseases. A comprehensive history and careful examination may lead to an earlier diagnosis, more appropriate treatment, and better outcome in cases of Pancoast tumor presenting with neuropathic or musculoskeletal pain.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-022-03328-4","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T10:08:37Z","timestamp":1647338917000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Pancoast tumor presenting with multiple joint pains: a case report"],"prefix":"10.1186","volume":"16","author":[{"given":"Safia","family":"Mohamud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mosunmola","family":"Oyawusi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger L.","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etuajie O.","family":"Halbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard M.","family":"Millis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teddy","family":"Gebremedhin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozra","family":"Dehkordi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,15]]},"reference":[{"key":"3328_CR1","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1001\/jama.1924.02660180025007","volume":"83","author":"HK Pancoast","year":"1924","unstructured":"Pancoast HK. Importance of careful roentgen ray investigations of apical chest tumors. JAMA. 1924;83:1407\u201311.","journal-title":"JAMA"},{"key":"3328_CR2","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1001\/jama.1932.02740690001001","volume":"99","author":"HK Pancoast","year":"1932","unstructured":"Pancoast HK. Superior pulmonary sulcus tumor: tumor characterized by pain, Horner\u2019s syndrome, destruction of bone and atrophy of hand muscles. JAMA. 1932;99:1391\u20136.","journal-title":"JAMA"},{"issue":"6","key":"3328_CR3","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1016\/S0003-4975(97)00360-3","volume":"63","author":"FC Detterbeck","year":"1997","unstructured":"Detterbeck FC. Pancoast (superior sulcus) tumors. Ann Thorac Surg. 1997;63(6):1810\u20138.","journal-title":"Ann Thorac Surg"},{"issue":"Suppl 4","key":"3328_CR4","first-page":"S342","volume":"5","author":"CN Foroulis","year":"2013","unstructured":"Foroulis CN, Zarogoulidis P, Darwiche K, Katsikogiannis N, Machairiotis N, Karapantzos I, et al. Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment. J Thorac Dis. 2013;5(Suppl 4):S342\u201358.","journal-title":"J Thorac Dis"},{"key":"3328_CR5","first-page":"1552","volume":"19","author":"J Tobias","year":"1932","unstructured":"Tobias J. Sindrome apico-costo-vertebral doloroso por tumor apexiano: su valor diagnostico en le cancer primitive pulmonary (Spanish). Rev Med Lat Am. 1932;19:1552\u20136.","journal-title":"Rev Med Lat Am"},{"key":"3328_CR6","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/j.ejcts.2009.04.036","volume":"36","author":"M Tamura","year":"2009","unstructured":"Tamura M, Hoda MA, Klepetko W. Current treatment paradigms of superior sulcus tumours. Eur J Cardio-Thoracic Surg. 2009;36:747\u201353.","journal-title":"Eur J Cardio-Thoracic Surg."},{"issue":"Suppl 1","key":"3328_CR7","first-page":"S108","volume":"6","author":"N Panagopoulos","year":"2014","unstructured":"Panagopoulos N, Leivaditis V, Koletsis E, Prokakis C, Alexopoulos P, Baltayiannis N, et al. Pancoast tumors: characteristics and preoperative assessment. J Thorac Dis. 2014;6(Suppl 1):S108\u201315.","journal-title":"J Thorac Dis"},{"key":"3328_CR8","first-page":"13","volume":"1","author":"R Komaki","year":"1991","unstructured":"Komaki R. Preoperative radiation therapy for superior sulcus lesions. Chest Surg Clin N Am. 1991;1:13\u201335.","journal-title":"Chest Surg Clin N Am"},{"key":"3328_CR9","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s40122-019-0124-2","volume":"8","author":"MR Jones","year":"2019","unstructured":"Jones MR, Prabhakar A, Viswanath O, Urits I, Green JB, Kendrick JB, et al. Thoracic outlet syndrome: a comprehensive review of pathophysiology, diagnosis, and treatment. Pain Ther. 2019;8:5\u201318.","journal-title":"Pain Ther"},{"issue":"3","key":"3328_CR10","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1007\/s10926-010-9278-9","volume":"21","author":"J Laulan","year":"2011","unstructured":"Laulan J, Fouquet B, Rodaix C, Jauffret P, Roquelaure Y, Descatha A. Thoracic outlet syndrome: definition, aetiological factors, diagnosis, management and occupational impact. J Occup Rehabil. 2011;21(3):366\u201373.","journal-title":"J Occup Rehabil"},{"key":"3328_CR11","first-page":"51","volume":"7","author":"A Pines","year":"1984","unstructured":"Pines A, Kaplinsky N, Olchovsky D, Frankl O. Rheumatoid arthritis-like syndrome: a presenting symptom of malignancy report of 3 cases and review of the literature. 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Scand J Rheumatol. 2001;30:40\u20134.","journal-title":"Scand J Rheumatol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03328-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-022-03328-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03328-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T10:18:21Z","timestamp":1647339501000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-022-03328-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,15]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["3328"],"URL":"https:\/\/doi.org\/10.1186\/s13256-022-03328-4","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,15]]},"assertion":[{"value":"16 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this Journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"109"}}