{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T03:07:33Z","timestamp":1771038453684,"version":"3.50.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T00:00:00Z","timestamp":1648425600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T00:00:00Z","timestamp":1648425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Neonates with severe acute respiratory syndrome coronavirus 2 infection are usually asymptomatic or have mild to moderate symptoms. Acute respiratory distress syndrome due to severe acute respiratory syndrome coronavirus 2 with respiratory insufficiency is rare. Therefore, information about the best intensive care strategy for neonates requiring mechanical ventilation is lacking. We report a neonatal case of severe acute respiratory distress syndrome, probably due to vertical transmission of severe acute respiratory syndrome coronavirus 2, complicated by <jats:italic>Staphylococcus aureus<\/jats:italic> sepsis. We aim to inform pediatric providers on the clinical course and acute management considerations in coronavirus disease-related neonatal acute respiratory distress syndrome.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A late preterm (gestational age 36 0\/7 weeks) Caucasian girl was born from a severe acute respiratory syndrome coronavirus 2-positive mother and tested positive for severe acute respiratory syndrome coronavirus 2 at 19\u00a0hours after birth. She developed acute respiratory distress syndrome requiring intensive care admission and mechanical ventilation. The clinical course was complicated by <jats:italic>S. aureus<\/jats:italic> pneumonia and bacteremia. Multimodal management included well-established interventions for respiratory distress syndrome such as surfactant therapy, high-frequency oscillatory ventilation, and inhaled nitric oxide, combined with therapies extrapolated from adult care for severe acute respiratory syndrome coronavirus 2 patients such as dexamethasone, coronavirus disease 2019-specific immunoglobins, and prophylactic low-molecular-weight heparin. The neonate was successfully weaned from the ventilator and improved clinically.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This case shows a rare but serious neonatal severe acute respiratory syndrome coronavirus 2 infection, leading to severe acute respiratory distress syndrome. Because of limited therapy guidelines for neonates, we suggest multimodal management with awareness of the possibility of <jats:italic>S. aureus<\/jats:italic> coinfection, to treat this age group successful.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-022-03364-0","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T16:03:20Z","timestamp":1648483400000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Management of severe neonatal respiratory distress due to vertical transmission of severe acute respiratory syndrome  coronavirus 2: a case report"],"prefix":"10.1186","volume":"16","author":[{"given":"Anne C.","family":"Verheijen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva E. R.","family":"Janssen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayke E.","family":"van der Putten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marieke W. P.","family":"van Horck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gijs T. J.","family":"van Well","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inge H. M.","family":"Van Loo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias C.","family":"H\u00fctten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Van Mechelen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,3,28]]},"reference":[{"issue":"7","key":"3364_CR1","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1007\/s00431-020-03684-7","volume":"179","author":"I Liguoro","year":"2020","unstructured":"Liguoro I, Pilotto C, Bonanni M, et al. SARS-COV-2 infection in children and newborns: a systematic review. Eur J Pediatr. 2020;179(7):1029\u201346.","journal-title":"Eur J Pediatr"},{"issue":"6","key":"3364_CR2","doi-asserted-by":"publisher","first-page":"e20200702","DOI":"10.1542\/peds.2020-0702","volume":"145","author":"Y Dong","year":"2020","unstructured":"Dong Y, Mo X, Hu Y, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020;145(6):e20200702.","journal-title":"Pediatrics"},{"issue":"10","key":"3364_CR3","doi-asserted-by":"publisher","first-page":"2565","DOI":"10.1002\/ppul.24991","volume":"55","author":"J Yasuhara","year":"2020","unstructured":"Yasuhara J, Kuno T, Takagi H, Sumitomo N. Clinical characteristics of COVID-19 in children: a systematic review. Pediatr Pulmonol. 2020;55(10):2565\u201375.","journal-title":"Pediatr Pulmonol"},{"issue":"10","key":"3364_CR4","doi-asserted-by":"publisher","first-page":"1948","DOI":"10.1111\/apa.15422","volume":"109","author":"AA Raba","year":"2020","unstructured":"Raba AA, Abobaker A, Elgenaidi IS, Daoud A. Novel coronavirus infection (COVID-19) in children younger than one year: a systematic review of symptoms, management and outcomes. Acta Paediatr. 2020;109(10):1948\u201355.","journal-title":"Acta Paediatr"},{"issue":"7","key":"3364_CR5","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1001\/jamapediatrics.2020.0878","volume":"174","author":"L Zeng","year":"2020","unstructured":"Zeng L, Xia S, Yuan W, et al. Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China. JAMA Pediatr. 2020;174(7):722\u20135.","journal-title":"JAMA Pediatr"},{"issue":"20","key":"3364_CR6","doi-asserted-by":"publisher","first-page":"2076","DOI":"10.1001\/jama.2021.5775","volume":"325","author":"M Norman","year":"2021","unstructured":"Norman M, Nav\u00e9r L, S\u00f6derling J, et al. Association of maternal SARS-CoV-2 infection in pregnancy with neonatal outcomes. JAMA. 2021;325(20):2076\u201386.","journal-title":"JAMA"},{"issue":"1","key":"3364_CR7","doi-asserted-by":"publisher","first-page":"5164","DOI":"10.1038\/s41467-020-18982-9","volume":"11","author":"R Raschetti","year":"2020","unstructured":"Raschetti R, Vivanti AJ, Vauloup-Fellous C, Loi B, Benachi A, De Luca D. Synthesis and systematic review of reported neonatal SARS-CoV-2 infections. Nat Commun. 2020;11(1):5164.","journal-title":"Nat Commun"},{"issue":"12","key":"3364_CR8","doi-asserted-by":"publisher","first-page":"e439","DOI":"10.1097\/INF.0000000000002941","volume":"39","author":"CR Correia","year":"2020","unstructured":"Correia CR, Marcal M, Vieira F, et al. Congenital SARS-CoV-2 infection in a neonate with severe acute respiratory syndrome. Pediatr Infect Dis J. 2020;39(12):e439\u201343.","journal-title":"Pediatr Infect Dis J"},{"issue":"11","key":"3364_CR9","doi-asserted-by":"publisher","first-page":"e367","DOI":"10.1097\/INF.0000000000002864","volume":"39","author":"C Trieu","year":"2020","unstructured":"Trieu C, Poole C, Cron RQ, et al. Severe neonatal coronavirus disease 2019 presenting as acute respiratory distress syndrome. Pediatr Infect Dis J. 2020;39(11):e367\u20139.","journal-title":"Pediatr Infect Dis J"},{"issue":"2","key":"3364_CR10","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S2352-4642(20)30342-4","volume":"5","author":"C Gale","year":"2021","unstructured":"Gale C, Quigley MA, Placzek A, et al. Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. Lancet Child Adolesc Health. 2021;5(2):113\u201321.","journal-title":"Lancet Child Adolesc Health."},{"key":"3364_CR11","doi-asserted-by":"publisher","first-page":"e6","DOI":"10.1016\/S2352-4642(21)00002-X","volume":"5","author":"F Gotzinger","year":"2021","unstructured":"Gotzinger F, Santiago-Garcia B, Fumado-Perez V, Brinkmann F, Tebruegge M, ptbnet C-SG. The ability of the neonatal immune response to handle SARS-CoV-2 infection. Lancet Child Adolesc Health. 2021;5:e6\u20137.","journal-title":"Lancet Child Adolesc Health"},{"issue":"9","key":"3364_CR12","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/S2352-4642(20)30177-2","volume":"4","author":"F Gotzinger","year":"2020","unstructured":"Gotzinger F, Santiago-Garcia B, Noguera-Julian A, et al. COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study. Lancet Child Adolesc Health. 2020;4(9):653\u201361.","journal-title":"Lancet Child Adolesc Health"},{"issue":"16","key":"3364_CR13","doi-asserted-by":"publisher","first-page":"2252","DOI":"10.1093\/cid\/ciaa619","volume":"71","author":"MR Tom","year":"2020","unstructured":"Tom MR, Mina MJ. To interpret the SARS-CoV-2 test, consider the cycle threshold value. Clin Infect Dis. 2020;71(16):2252\u20134.","journal-title":"Clin Infect Dis"},{"key":"3364_CR14","doi-asserted-by":"publisher","first-page":"9","DOI":"10.25259\/JCIS_192_2020","volume":"11","author":"D Penha","year":"2021","unstructured":"Penha D, Pinto EG, Matos F, et al. CO-RADS: coronavirus classification review. J Clin Imaging Sci. 2021;11:9.","journal-title":"J Clin Imaging Sci."},{"issue":"8","key":"3364_CR15","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1016\/S2213-2600(17)30214-X","volume":"5","author":"D De Luca","year":"2017","unstructured":"De Luca D, van Kaam AH, Tingay DG, et al. The Montreux definition of neonatal ARDS: biological and clinical background behind the description of a new entity. Lancet Respir Med. 2017;5(8):657\u201366.","journal-title":"Lancet Respir Med"},{"key":"3364_CR16","unstructured":"Deville JG, Song E, Ouellette CP. COVID-19: management in children. 2021. https:\/\/www.uptodate.com\/contents\/covid-19-management-in-children. Accessed 19 Nov 2021."},{"key":"3364_CR17","unstructured":"NethOSS. Update registratie COVID-19 positieve zwangeren in NethOSS. 2021. https:\/\/www.nvog.nl\/actueel\/registratie-van-covid-19-positieve-zwangeren-in-nethoss\/. Updated 13th Oct 2021. Accessed."},{"key":"3364_CR18","doi-asserted-by":"crossref","unstructured":"Mand N, Iannaccone A, Longardt A-C, et al. Neonatal outcome following maternal infection with SARS-CoV-2 in Germany: COVID-19-related obstetric and neonatal outcome study (CRONOS). Arch Dis Child Fetal Neonatal Edn. 2021:fetalneonatal-2021-322100.","DOI":"10.1136\/archdischild-2021-322100"},{"issue":"6","key":"3364_CR19","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1111\/apa.15270","volume":"109","author":"JF Ludvigsson","year":"2020","unstructured":"Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020;109(6):1088\u201395.","journal-title":"Acta Paediatr"},{"issue":"7","key":"3364_CR20","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1016\/j.cmi.2020.04.023","volume":"26","author":"M Cevik","year":"2020","unstructured":"Cevik M, Bamford CGG, Ho A. COVID-19 pandemic-a focused review for clinicians. Clin Microbiol Infect. 2020;26(7):842\u20137.","journal-title":"Clin Microbiol Infect"},{"key":"3364_CR21","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.ijid.2021.02.087","volume":"105","author":"V Singh","year":"2021","unstructured":"Singh V, Upadhyay P, Reddy J, Granger J. SARS-CoV-2 respiratory co-infections: incidence of viral and bacterial co-pathogens. Int J Infect Dis. 2021;105:617\u201320.","journal-title":"Int J Infect Dis"},{"issue":"3","key":"3364_CR22","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.ccc.2011.04.005","volume":"27","author":"K Raghavendran","year":"2011","unstructured":"Raghavendran K, Willson D, Notter RH. Surfactant therapy for acute lung injury and acute respiratory distress syndrome. Crit Care Clin. 2011;27(3):525\u201359.","journal-title":"Crit Care Clin"},{"key":"3364_CR23","doi-asserted-by":"publisher","first-page":"101413","DOI":"10.1016\/j.cocis.2020.101413","volume":"51","author":"A Ghati","year":"2021","unstructured":"Ghati A, Dam P, Tasdemir D, et al. Exogenous pulmonary surfactant: a review focused on adjunctive therapy for SARS CoV-2 including SP-A and SP-D as added clinical marker. Curr Opin Colloid Interface Sci. 2021;51:101413.","journal-title":"Curr Opin Colloid Interface Sci"},{"issue":"1","key":"3364_CR24","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1186\/s13054-020-03268-9","volume":"24","author":"P Schousboe","year":"2020","unstructured":"Schousboe P, Wiese L, Heiring C, et al. Assessment of pulmonary surfactant in COVID-19 patients. Crit Care. 2020;24(1):552.","journal-title":"Crit Care"},{"issue":"5","key":"3364_CR25","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1080\/17476348.2021.1865809","volume":"15","author":"RAW Veldhuizen","year":"2021","unstructured":"Veldhuizen RAW, Zuo YY, Petersen NO, Lewis JF, Possmayer F. The COVID-19 pandemic: a target for surfactant therapy? Expert Rev Respir Med. 2021;15(5):597\u2013608.","journal-title":"Expert Rev Respir Med"},{"issue":"13","key":"3364_CR26","doi-asserted-by":"publisher","first-page":"1330","DOI":"10.1001\/jama.2020.17023","volume":"324","author":"Group. TWREAfC-TRW","year":"2020","unstructured":"Group. TWREAfC-TRW. Association between administration of systemic corticosteroids and mortality among critically ill patients with COVID-19: a meta-analysis. JAMA. 2020;324(13):1330\u201341.","journal-title":"JAMA"},{"issue":"1","key":"3364_CR27","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1542\/peds.2004-2843","volume":"117","author":"LW Doyle","year":"2006","unstructured":"Doyle LW, Davis PG, Morley CJ, McPhee A, Carlin JB, DART Study Investigators. Low-dose dexamethasone facilitates extubation among chronically ventilator-dependent infants: a multicenter, international, randomized, controlled trial. Pediatrics. 2006;117(1):75\u201383.","journal-title":"Pediatrics"},{"issue":"3","key":"3364_CR28","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/s15010-020-01553-x","volume":"49","author":"A Elabbadi","year":"2021","unstructured":"Elabbadi A, Turpin M, Gerotziafas GT, Teulier M, Voiriot G, Fartoukh M. Bacterial coinfection in critically ill COVID-19 patients with severe pneumonia. Infection. 2021;49(3):559\u201362.","journal-title":"Infection"},{"key":"3364_CR29","unstructured":"Organization WH. Clinical management of COVID-19: interim guidance. 2020. Update 25 Jan 2021."},{"issue":"4","key":"3364_CR30","first-page":"Cd004085","volume":"4","author":"S Sud","year":"2016","unstructured":"Sud S, Sud M, Friedrich JO, et al. High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome. Cochrane Database Syst Rev. 2016;4(4):Cd004085.","journal-title":"Cochrane Database Syst Rev"},{"key":"3364_CR31","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.freeradbiomed.2020.12.008","volume":"163","author":"W Fang","year":"2021","unstructured":"Fang W, Jiang J, Su L, Shu T, Liu H, Lai S, Ghiladi RA, Wang J. The role of NO in COVID-19 and potential therapeutic strategies. Free Radic Biol Med. 2021;163:153\u201362.","journal-title":"Free Radic Biol Med"},{"issue":"5","key":"3364_CR32","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1111\/aas.13757","volume":"65","author":"C Lotz","year":"2021","unstructured":"Lotz C, Muellenbach RM, Meybohm P, et al. Effects of inhaled nitric oxide in COVID-19-induced ARDS\u2014is it worthwhile? Acta Anaesthesiol Scand. 2021;65(5):629\u201332.","journal-title":"Acta Anaesthesiol Scand"},{"issue":"6","key":"3364_CR33","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1093\/jpids\/piaa098","volume":"9","author":"DE Dulek","year":"2020","unstructured":"Dulek DE, Fuhlbrigge RC, Tribble AC, et al. Multidisciplinary guidance regarding the use of immunomodulatory therapies for acute COVID-19 in pediatric patients. J Pediatr Infect Dis Soc. 2020;9(6):716\u201337.","journal-title":"J Pediatr Infect Dis Soc"},{"issue":"18","key":"3364_CR34","doi-asserted-by":"publisher","first-page":"4278","DOI":"10.1182\/bloodadvances.2020002507","volume":"4","author":"Z Rodriguez","year":"2020","unstructured":"Rodriguez Z, Shane AL, Verkerke H, et al. COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease. Blood Adv. 2020;4(18):4278\u201381.","journal-title":"Blood Adv"},{"issue":"6","key":"3364_CR35","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s15010-020-01493-6","volume":"49","author":"R Kulkarni","year":"2021","unstructured":"Kulkarni R, Rajput U, Dawre R, et al. Early-onset symptomatic neonatal COVID-19 infection with high probability of vertical transmission. Infection. 2021;49(6):339\u201343.","journal-title":"Infection"},{"key":"3364_CR36","doi-asserted-by":"publisher","first-page":"287","DOI":"10.3389\/fped.2020.00287","volume":"8","author":"YC Yu","year":"2020","unstructured":"Yu YC. P Coronavirus Disease 2019 (COVID-19) in neonates and children from China: a review. Front Pediatr. 2020;8:287.","journal-title":"Front Pediatr"},{"issue":"5","key":"3364_CR37","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1111\/aogs.13870","volume":"99","author":"PS Shah","year":"2020","unstructured":"Shah PS, Diambomba Y, Acharya G, Morris SK, Bitnun A. Classification system and case definition for SARS-CoV-2 infection in pregnant women, fetuses, and neonates. Acta Obstet Gynecol Scand. 2020;99(5):565\u20138.","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"3364_CR38","doi-asserted-by":"publisher","first-page":"100107","DOI":"10.1016\/j.ajogmf.2020.100107","volume":"2","author":"D Di Mascio","year":"2020","unstructured":"Di Mascio D, Khalil A, Saccone G, et al. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2020;2(2):100107.","journal-title":"Am J Obstet Gynecol MFM"},{"issue":"1","key":"3364_CR39","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s40001-020-00439-w","volume":"25","author":"K Diriba","year":"2020","unstructured":"Diriba K, Awulachew E, Getu E. The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis. Eur J Med Res. 2020;25(1):39.","journal-title":"Eur J Med Res"},{"issue":"4","key":"3364_CR40","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1159\/000509290","volume":"85","author":"H Akhtar","year":"2020","unstructured":"Akhtar H, Patel C, Abuelgasim E, Harky A. COVID-19 (SARS-CoV-2) infection in pregnancy: a systematic review. Gynecol Obstet Invest. 2020;85(4):295\u2013306.","journal-title":"Gynecol Obstet Invest"},{"issue":"8","key":"3364_CR41","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1055\/s-0040-1710050","volume":"37","author":"MC Alzamora","year":"2020","unstructured":"Alzamora MC, Paredes T, Caceres D, Webb CM, Valdez LM, La Rosa M. Severe COVID-19 during pregnancy and possible vertical transmission. Am J Perinatol. 2020;37(8):861\u20135.","journal-title":"Am J Perinatol"},{"issue":"9","key":"3364_CR42","doi-asserted-by":"publisher","first-page":"e265","DOI":"10.1097\/INF.0000000000002815","volume":"39","author":"J Sisman","year":"2020","unstructured":"Sisman J, Jaleel MA, Moreno W, et al. Intrauterine transmission of SARS-COV-2 infection in a preterm infant. Pediatr Infect Dis J. 2020;39(9):e265\u20137.","journal-title":"Pediatr Infect Dis J"},{"key":"3364_CR43","doi-asserted-by":"publisher","first-page":"573468","DOI":"10.3389\/fmed.2020.573468","volume":"7","author":"MM Islam","year":"2020","unstructured":"Islam MM, Poly TN, Walther BA, et al. Clinical characteristics and neonatal outcomes of pregnant patients with COVID-19: a systematic review. Front Med (Lausanne). 2020;7:573468.","journal-title":"Front Med (Lausanne)"},{"issue":"3","key":"3364_CR44","doi-asserted-by":"publisher","first-page":"100145","DOI":"10.1016\/j.ajogmf.2020.100145","volume":"2","author":"L Patan\u00e8","year":"2020","unstructured":"Patan\u00e8 L, Morotti D, Giunta MR, et al. Vertical transmission of coronavirus disease 2019: severe acute respiratory syndrome coronavirus 2 RNA on the fetal side of the placenta in pregnancies with coronavirus disease 2019-positive mothers and neonates at birth. Am J Obstet Gynecol MFM. 2020;2(3):100145.","journal-title":"Am J Obstet Gynecol MFM"},{"issue":"1","key":"3364_CR45","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.ajog.2020.07.049","volume":"224","author":"AM Kotlyar","year":"2021","unstructured":"Kotlyar AM, Grechukhina O, Chen A, et al. Vertical transmission of coronavirus disease 2019: a systematic review and meta-analysis. Am J Obstet Gynecol. 2021;224(1):35-53.e33.","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"3364_CR46","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s15010-020-01531-3","volume":"49","author":"B Salzberger","year":"2021","unstructured":"Salzberger B, Buder F, Lampl B, et al. Epidemiology of SARS-CoV-2. Infection. 2021;49(2):233\u20139.","journal-title":"Infection"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03364-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-022-03364-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03364-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,22]],"date-time":"2022-10-22T11:43:22Z","timestamp":1666439002000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-022-03364-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,28]]},"references-count":46,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["3364"],"URL":"https:\/\/doi.org\/10.1186\/s13256-022-03364-0","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,28]]},"assertion":[{"value":"18 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The paper is exempt from ethical committee approval because it is a case description with initially just an intention to treat and not for research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s legal guardian for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"140"}}