{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T23:41:09Z","timestamp":1653262869369},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T00:00:00Z","timestamp":1653264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T00:00:00Z","timestamp":1653264000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Pyoderma gangrenosum and cutaneous squamous cell carcinoma are two conditions well reported in the literature and may exist concurrently in the same patient. In fact, there have been reports of misdiagnosis of one for the other. The two conditions occurring in the same location, however, has not yet been reported.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case description<\/jats:title>\n                <jats:p>We report the case of a 57-year-old Caucasian male with history of pyoderma gangrenosum of the right lateral tibial area who developed squamous cell carcinoma of verrucous type at the same site. Excisional surgery was considered to treat this patient, but he was ultimately managed with radiation therapy to the affected area due to the size of the lesion and the risk of triggering proliferation of the pyoderma gangrenosum.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>We hope that this case report will add to the literature of both conditions, show a unique presentation of both conditions, and emphasize the inclusion of both pyoderma gangrenosum and squamous cell carcinoma when developing a differential diagnosis of a chronic, nonhealing wound.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-022-03412-9","type":"journal-article","created":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T23:03:46Z","timestamp":1653260626000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Squamous cell carcinoma of verrucous type in the setting of prior pyoderma gangrenosum: a case report"],"prefix":"10.1186","volume":"16","author":[{"given":"Amy","family":"Morrison","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlene","family":"Waters-Hollingsworth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Mabel","family":"Gamboa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,23]]},"reference":[{"key":"3412_CR1","unstructured":"Skin Cancer Facts & Statistics. The Skin Cancer Foundation. https:\/\/www.skincancer.org\/skin-cancer-information\/skin-cancer-facts\/ (2021). Accessed July 10 2021."},{"issue":"6","key":"3412_CR2","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1016\/j.jaad.2017.11.063","volume":"79","author":"HJ Ashchyan","year":"2018","unstructured":"Ashchyan HJ, Nelson CA, Stephen S, James WD, Micheletti RG, Rosenbach M. Neutrophilic dermatoses: pyoderma gangrenosum and other bowel- and arthritis-associated neutrophilic dermatoses. J Am Acad Dermatol. 2018;79(6):1009\u201322.","journal-title":"J Am Acad Dermatol"},{"key":"3412_CR3","doi-asserted-by":"publisher","DOI":"10.5070\/d3274053158","author":"H Tsibris","year":"2021","unstructured":"Tsibris H, Lian C, Ho A. Pembrolizumab-associated pyoderma gangrenosum in a patient with metastatic squamous cell carcinoma. Dermatol Online J. 2021. https:\/\/doi.org\/10.5070\/d3274053158.","journal-title":"Dermatol Online J"},{"issue":"9","key":"3412_CR4","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1016\/j.jhsa.2012.06.019","volume":"37","author":"CM Wolfe","year":"2012","unstructured":"Wolfe CM, Green WH, Cognetta AB, Baniahmad O, Hatfield HK. Atypical pyoderma gangrenosum of the dorsal hand mimicking squamous cell carcinoma. J Hand Surg. 2012;37(9):1835\u20138. https:\/\/doi.org\/10.1016\/j.jhsa.2012.06.019.","journal-title":"J Hand Surg"},{"issue":"3","key":"3412_CR5","first-page":"208","volume":"23","author":"T \u010cuk Radovi\u0107","year":"2015","unstructured":"\u010cuk Radovi\u0107 T, Kostovi\u0107 K, Rado\u0161 J, Pa\u0161tar Z, Pavli\u0161a G, Marinovi\u0107 B. Advanced pyoderma gangrenosum previously treated as squamous cell carcinoma. Acta Dermatovenerol Croat. 2015;23(3):208\u201312.","journal-title":"Acta Dermatovenerol Croat"},{"issue":"5","key":"3412_CR6","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.ad.2018.02.022","volume":"110","author":"M Gonz\u00e1lez-Sab\u00edn","year":"2019","unstructured":"Gonz\u00e1lez-Sab\u00edn M, Rodr\u00edguez-D\u00edaz E, Gonzalvo-Rodr\u00edguez P, Astola-Hidalgo I. Pioderma gangrenoso simulando un carcinoma epidermoide. Actas Dermosifiliogr. 2019;110(5):400\u20132.","journal-title":"Actas Dermosifiliogr"},{"key":"3412_CR7","doi-asserted-by":"publisher","DOI":"10.1056\/nejmicm1410236","author":"S Emmert","year":"2015","unstructured":"Emmert S, Sch\u00f6n MP. Squamous-cell carcinoma resembling pyoderma gangrenosum. N Engl J Med. 2015. https:\/\/doi.org\/10.1056\/nejmicm1410236.","journal-title":"N Engl J Med"},{"issue":"3","key":"3412_CR8","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1111\/ajd.13020","volume":"60","author":"G Khullar","year":"2019","unstructured":"Khullar G, Mittal S, Sharma S. Verrucous carcinoma on the foot arising in a chronic neuropathic ulcer of leprosy. Australas J Dermatol. 2019;60(3):245\u20136. https:\/\/doi.org\/10.1111\/ajd.13020.","journal-title":"Australas J Dermatol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03412-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-022-03412-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03412-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T23:04:09Z","timestamp":1653260649000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-022-03412-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,23]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["3412"],"URL":"https:\/\/doi.org\/10.1186\/s13256-022-03412-9","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,23]]},"assertion":[{"value":"27 September 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"199"}}