{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T17:38:23Z","timestamp":1654105103645},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Ectopic intrathyroidal thymic tissue is a rare diagnosis, specifically in adults. Such ectopic tissue is usually misdiagnosed as benign or malignant thyroid lesions and is mainly investigated by ultrasonography and pathologic examination.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We present the case of an adult 31-year-old Persian female patient with a cervical mass and no other significant medical history. The lesion had hypo- to isoechoic features on sonographic imaging, and needle aspiration examination revealed lymphoid cells suspicious of lymphoid malignancies. However, pathologic examination after resection of the lesion showed normal thymic tissue.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The rare entity of ectopic thymic tissue within the thyroid gland in adult patients requires meticulous examination by clinicians, radiologists, and pathologists to diagnose the condition with high accuracy and plan appropriate management.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-022-03434-3","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T23:04:44Z","timestamp":1653433484000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ectopic intrathyroidal thymic tissue in an adult patient: a case report and review of the\u00a0literature"],"prefix":"10.1186","volume":"16","author":[{"given":"Sadegh","family":"Moradian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sina","family":"Delazar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzad","family":"Yazdani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Mohammadzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,25]]},"reference":[{"issue":"5","key":"3434_CR1","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1089\/thy.2014.0367","volume":"25","author":"T Fukushima","year":"2015","unstructured":"Fukushima T, Suzuki S, Ohira T, Shimura H, Midorikawa S, Ohtsuru A, et al. Prevalence of ectopic intrathyroidal thymus in Japan: the Fukushima Health Management Survey. Thyroid. 2015;25(5):534\u20137.","journal-title":"Thyroid"},{"issue":"5","key":"3434_CR2","doi-asserted-by":"publisher","first-page":"547","DOI":"10.4132\/KoreanJPathol.2011.45.5.547","volume":"45","author":"WS Moon","year":"2011","unstructured":"Moon WS, Hwang SB, Hong KH. Intrathyroidal thymic tissue in an adult. Korean J Pathol. 2011;45(5):547.","journal-title":"Korean J Pathol"},{"issue":"6","key":"3434_CR3","doi-asserted-by":"publisher","first-page":"842","DOI":"10.5858\/2001-125-0842-AETATT","volume":"125","author":"SL Wu","year":"2001","unstructured":"Wu SL, Gupta D, Connelly J. Adult ectopic thymus adjacent to thyroid and parathyroid. Arch Pathol Lab Med. 2001;125(6):842\u20133.","journal-title":"Arch Pathol Lab Med"},{"issue":"6","key":"3434_CR4","doi-asserted-by":"publisher","first-page":"726","DOI":"10.21037\/gs.2017.08.11","volume":"6","author":"K O'Connor","year":"2017","unstructured":"O\u2019Connor K, Alzahrani H, Murad F, Daroca P, Kandil E. An ectopic intrathyroidal thymic tissue and intrathymic parathyroid tissue in a patient with Graves disease. Gland Surg. 2017;6(6):726\u20138.","journal-title":"Gland Surg"},{"key":"3434_CR5","doi-asserted-by":"crossref","unstructured":"Bang MH, Shin J, Lee KS, Kang MJ. Intrathyroidal ectopic thymus in children: a benign lesion. Medicine (Baltimore). 2018;97(14):e0282.","DOI":"10.1097\/MD.0000000000010282"},{"issue":"9","key":"3434_CR6","first-page":"6375","volume":"7","author":"A Kim","year":"2014","unstructured":"Kim A, Kang SH, Bae YK. Ectopic intrathyroidal thymus accompanied by intrathyroidal parathyroid as a cause of a solitary thyroid nodule in adult. Int J Clin Exp Pathol. 2014;7(9):6375\u20138.","journal-title":"Int J Clin Exp Pathol"},{"key":"3434_CR7","first-page":"17","volume":"2017","author":"G Velimezis","year":"2017","unstructured":"Velimezis G, Ioannidis A, Apostolakis S, Chorti M, Avramidis C, Papachristou E. Concurrent intrathyroidal thymus and parathyroid in a patient with papillary thyroid carcinoma: a challenging diagnosis. Endocrinol Diabetes Metab Case Rep. 2017;2017:17\u20130015.","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"issue":"3","key":"3434_CR8","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1002\/jum.14360","volume":"37","author":"MC Frates","year":"2018","unstructured":"Frates MC, Benson CB, Dorfman DM, Cibas ES, Huang SA. Ectopic intrathyroidal thymic tissue mimicking thyroid nodules in children. J Ultrasound Med. 2018;37(3):783\u201391.","journal-title":"J Ultrasound Med"},{"issue":"2","key":"3434_CR9","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1309\/VM7E52B6U9Q729DQ","volume":"127","author":"Y Ito","year":"2007","unstructured":"Ito Y, Miyauchi A, Nakamura Y, Miya A, Kobayashi K, Kakudo K. Clinicopathologic significance of intrathyroidal epithelial thymoma\/carcinoma showing thymus-like differentiation: a collaborative study with Member Institutes of the Japanese Society of Thyroid Surgery. Am J Clin Pathol. 2007;127(2):230\u20136.","journal-title":"Am J Clin Pathol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03434-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-022-03434-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-022-03434-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T23:04:54Z","timestamp":1653433494000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-022-03434-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,25]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["3434"],"URL":"https:\/\/doi.org\/10.1186\/s13256-022-03434-3","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,25]]},"assertion":[{"value":"12 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The ethical committee of the Tehran University of Medical Sciences approved this case report; however, the institution does not provide ethical codes for case reports. Also, the patient described in this case report provided informed consent about participation in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors of this case report declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"224"}}