{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:27:43Z","timestamp":1779917263898,"version":"3.53.1"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Pulmonary actinomycosis is a chronic disease characterized by abscess formation, draining sinuses, fistulae, and tissue fibrosis. It can mimic other conditions, particularly malignant and granulomatous diseases, and is perhaps extremely challenging to diagnose.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 64-year-old Japanese man presented with 6-week history of a painful solid lump in the chest wall. Chest computed tomography scan revealed a mass-like consolidation in the left upper lobe, with rib erosion and direct extension into the anterior chest wall. <jats:sup>18<\/jats:sup>F-fluorodeoxyglucose positron emission tomography scan showed increased metabolic activity in the mass, which is indicative of primary lung cancer. The bronchoscopy and computed tomography scan-guided transthoracic biopsy results were considered nondiagnostic. Finally, the patient was diagnosed with pulmonary actinomycosis via surgical resection. He completed an 8-week course of antibiotic therapy and experienced no recurrence.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>There is no difference in positron emission tomography\/computed tomography scan findings between actinomycosis and malignancy. Therefore, pulmonary actinomycosis should be considered in the differential diagnosis of cases involving intensive activity on <jats:sup>18<\/jats:sup>F-fluorodeoxyglucose positron emission tomography scan.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-022-03481-w","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:03:03Z","timestamp":1656633783000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Pulmonary actinomycosis mimicking lung cancer on 18F-fluorodeoxyglucose positron emission tomography: a case report"],"prefix":"10.1186","volume":"16","author":[{"given":"Shinichi","family":"Miyazaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeo","family":"Fujito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasumasa","family":"Kuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junzo","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiharu","family":"Nara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,1]]},"reference":[{"key":"3481_CR1","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1183\/09031936.03.00089103","volume":"21","author":"GF Mabeza","year":"2003","unstructured":"Mabeza GF, Macfarlane J. Pulmonary actinomycosis. Eur Respir J. 2003;21:545\u201351.","journal-title":"Eur Respir J"},{"key":"3481_CR2","doi-asserted-by":"publisher","first-page":"825","DOI":"10.5588\/ijtld.16.0773","volume":"21","author":"M Zhang","year":"2017","unstructured":"Zhang M, Zhang XY, Chen YB. Primary pulmonary actinomycosis: a retrospective analysis of 145 cases in mainland China. Int J Tuberc Lung Dis. 2017;21:825\u201331.","journal-title":"Int J Tuberc Lung Dis"},{"key":"3481_CR3","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1148\/radiology.209.1.9769836","volume":"209","author":"JE Cheon","year":"1998","unstructured":"Cheon JE, Im JG, Kim MY, et al. Thoracic actinomycosis: CT findings. Radiology. 1998;209:229\u201333.","journal-title":"Radiology"},{"key":"3481_CR4","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1136\/bmj.294.6581.1199","volume":"294","author":"J Haynes","year":"1987","unstructured":"Haynes J, Greenstone MA. 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Pulmonary actinomycosis during the first decade of 21st century: cases of 94 patients. BMC Infect Dis. 2013;13:216.","journal-title":"BMC Infect Dis"},{"key":"3481_CR10","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.3348\/kjr.2015.16.6.1262","volume":"16","author":"L Qiu","year":"2015","unstructured":"Qiu L, Lan L, Feng Y, et al. Pulmonary actinomycosis imitating lung cancer on (18)F-FDG PET\/CT: a case report and literature review. Korean J Radiol. 2015;16:1262\u20135.","journal-title":"Korean J Radiol"},{"key":"3481_CR11","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1097\/00003072-199907000-00016","volume":"24","author":"CJ Hoekstra","year":"1999","unstructured":"Hoekstra CJ, Hoekstra OS, Teengs JP, et al. Thoracic actinomycosis imaging with fluorine-18 fluorodeoxyglucose positron emission tomography. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"255"}}