{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:36:01Z","timestamp":1792100161718,"version":"4.4.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T00:00:00Z","timestamp":1659139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T00:00:00Z","timestamp":1659139200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"none"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Aggressive angiomyxoma (AAM) is a locally infiltrative mesenchymal tumour that most commonly affects the pelvis and\/or perineum in adult women. AAM is very rare in males, especially in infancy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 10-month-old fulani (African) male infant was referred to our department for a large painless mass in the right testicule. The mass was detected during the neonatal period and gradually increased in size. Ultrasound examination revealed a large heterogeneous lesion; computed tomography results led to the conclusion that the mass was a mesenteric hernia. An inguinal and scrotal surgical approach was adopted. Exploratory surgery found a normal right testicle displaced upwardly and a large scrotal mass. Radical excision of the mass and orchidopexy were performed. Subsequent histology and immunohistochemstry studies indicated that the mass was a scrotal angiomyxoma. The postoperative course was uneventful. No recurrence occurred during the 6-month follow-up<jats:bold>.<\/jats:bold><\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>To the best of our knowledge, this is the youngest patient with AAM reported to date. Angiomyxoma should be included in the differential diagnosis of scrotal masses, for which radical excision is justifiable to prevent recurrence.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-022-03497-2","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T23:03:28Z","timestamp":1659135808000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Aggressive angiomyxoma as\u00a0a rare cause of scrotum enlargement in a 10-month-old boy: a case report"],"prefix":"10.1186","volume":"16","author":[{"given":"L\u00e9onidas","family":"Nyandwi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salahoudine","family":"Idrissa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hell\u00e9","family":"Moustapha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahamoud Omid Ali","family":"Ada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efared","family":"Boubacar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idrissa","family":"Boubacar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakhama","family":"Abdelfatteh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ksia","family":"Amine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abarchi","family":"Habibou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,30]]},"reference":[{"issue":"2","key":"3497_CR1","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1080\/014850102317267409","volume":"48","author":"FP Chuang","year":"2002","unstructured":"Chuang FP, Wu ST, Lee SS, et al. Aggressive angiomyxoma of the scrotum. Arch Androl janv. 2002;48(2):101\u20136.","journal-title":"Arch Androl. janv"},{"key":"3497_CR2","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.urology.2020.05.028","volume":"144","author":"KK Korecka","year":"2020","unstructured":"Korecka KK, Hyla-Klekot LE, Kudela GP, Pale\u0144 PA, Kajor MW, Koszutski TK. Aggressive angiomyxoma in an 11-year-old boy\u2014diagnostic and therapeutic dilemmas: an unusual case report and review of the literature. Urology. 2020;144:205\u20137.","journal-title":"Urology"},{"issue":"1","key":"3497_CR3","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1111\/ajd.13158","volume":"61","author":"R Koito","year":"2020","unstructured":"Koito R, Kohda F, Dugu L, Suenaga A, Ichiki T, Furue M. Scrotal angiomyxoma. Australas J Dermatol. 2020;61(1):78\u20139.","journal-title":"Australas J Dermatol"},{"key":"3497_CR4","doi-asserted-by":"publisher","unstructured":"Kirkilessis G, Kakavia K, Bougiouklis D, Papadopoulos A, Lampropoulos C, Kirkilessis I. Aggressive angiomyxoma to 57-year old man. J Surg Case Rep. 2020;2020(9):rjaa313. https:\/\/doi.org\/10.1093\/jscr\/rjaa313.","DOI":"10.1093\/jscr\/rjaa313"},{"issue":"3","key":"3497_CR5","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1177\/229255030701500301","volume":"15","author":"LA Andres","year":"2007","unstructured":"Andres LA, Mishra MJ. Angiomyxoma diagnosed in a man presenting for abdominal lipectomy. Can J Plast Surg J Can Chir Plast. 2007;15(3):163\u20134.","journal-title":"Can J Plast Surg J Can Chir Plast."},{"issue":"10","key":"3497_CR6","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1016\/S0344-0338(00)80124-7","volume":"196","author":"A Sk\u00e1lov\u00e1","year":"2000","unstructured":"Sk\u00e1lov\u00e1 A, Z\u00e1me\u010dn\u00edk M, Michal M, Opatrny V. Aggressive angiomyxoma presenting as polyp of uterine cavity. Pathol Res Pract. 2000;196(10):719\u201325.","journal-title":"Pathol Res Pract"},{"key":"3497_CR7","doi-asserted-by":"publisher","unstructured":"Aydin AM, Katipoglu K, Baydar DE, Bilen CY. Long-standing aggressive angiomyxoma as a paratesticular mass: a case report and review of literature. SAGE Open Med Case Rep. 2017;5:2050313X17712090. https:\/\/doi.org\/10.1177\/2050313X17712090.","DOI":"10.1177\/2050313X17712090"},{"issue":"2","key":"3497_CR8","doi-asserted-by":"publisher","first-page":"197","DOI":"10.4103\/UA.UA_168_16","volume":"9","author":"MI Ismail","year":"2017","unstructured":"Ismail MI, Wong YP, Tan GH, Fam XI. Paratesticular aggressive angiomyxoma: a rare case. Urol Ann. 2017;9(2):197\u20139.","journal-title":"Urol Ann"},{"key":"3497_CR9","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.urology.2016.10.034","volume":"101","author":"M Kawamura","year":"2017","unstructured":"Kawamura M, Matsumoto F, Matsui F, Yazawa K, Shimada K. Aggressive angiomyxoma of the vulva mimicking clitoromegaly in a young child. Urology. 2017;101:142\u20134.","journal-title":"Urology"},{"key":"3497_CR10","doi-asserted-by":"crossref","unstructured":"Neyaz A, Husain N, Anand N, Srivastava P. Rare paratesticular aggressive angiomyxoma with negative oestrogen and progesterone receptors in a male patient. BMJ Case Rep. 2018;2018:bcr2017222164.","DOI":"10.1136\/bcr-2017-222164"},{"issue":"2","key":"3497_CR11","doi-asserted-by":"publisher","first-page":"e237","DOI":"10.1016\/j.clgc.2015.12.022","volume":"14","author":"DL Draeger","year":"2016","unstructured":"Draeger DL, Protzel C, Hakenberg OW. Aggressive angiomyxoma as a rare differential diagnosis of enlargement of the scrotum. Clin Genitourin Cancer. 2016;14(2):e237\u20139.","journal-title":"Clin Genitourin Cancer"},{"key":"3497_CR12","doi-asserted-by":"crossref","unstructured":"Kim H-S, Park S-H, Chi JG. Aggressive angiomyxoma of childhood: two unusual cases developed in the scrotum. 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A copy of the written consent will be available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"293"}}