{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T23:21:12Z","timestamp":1783034472467,"version":"3.54.6"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Kimura\u2019s disease is a rare chronic inflammatory disorder of unknown etiology that is seen in people of Asian descent. It is characterized by head and neck subcutaneous nodules along with lymphadenopathy, which is usually solitary but can be generalized. It is diagnosed histopathologically by the proliferation of blood vessels and germinal centers in lymphoid follicles, along with variable degrees of fibrosis and extensive eosinophil infiltration. Its localized form is treated with surgical excision, while generalized lesions and those that do not respond to surgical excision can be managed with steroids or radiotherapy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case<\/jats:title>\n                <jats:p>In this report, we present the first case of Kimura\u2019s disease in the Ethiopian literature in a 40-year-old Ethiopian man that presented with generalized pruritic subcutaneous nodules and lymphadenopathy, which were effectively managed with a tapering course of prednisolone, and a relapse that showed good sustained response with slow steroid taper.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We have\u00a0demonstrated that, even though it is very rare in the African continent, Kimura\u2019s disease is to be considered as a differential diagnosis for patients that present with subcutaneous nodules and lymphadenopathy. We also have\u00a0demonstrated that relapses can be effectively managed with reinitiation of the same dose of steroids but with a very slow taper.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04352-2","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T01:02:16Z","timestamp":1707181336000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Kimura\u2019s disease: a case report"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9830-3864","authenticated-orcid":false,"given":"Zablon Mesfin","family":"Anbessie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"issue":"1","key":"4352_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12893-019-0673-7","volume":"20","author":"G Zhang","year":"2020","unstructured":"Zhang G, Li X, Sun G, Cao Y, Gao N, Qi W. Clinical analysis of Kimura\u2019s disease in 24 cases from China. BMC Surg. 2020;20(1):1\u20136. https:\/\/doi.org\/10.1186\/s12893-019-0673-7.","journal-title":"BMC Surg"},{"key":"4352_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4061\/2010\/673908","volume":"2010","author":"MA Fouda","year":"2010","unstructured":"Fouda MA, Gheith O, Refaie A, et\u00a0al. Kimura disease: a case report and review of the literature with a new management protocol. Int J Nephrol. 2010;2010:1\u20134. https:\/\/doi.org\/10.4061\/2010\/673908.","journal-title":"Int J Nephrol"},{"issue":"2","key":"4352_CR3","doi-asserted-by":"publisher","first-page":"195","DOI":"10.15386\/cjmed-1030","volume":"92","author":"H Dhingra","year":"2019","unstructured":"Dhingra H, Nagpal R, Baliyan A, Alva SR. Kimura disease: case report and brief review of the literature. Med Pharm Reports. 2019;92(2):195\u20139. https:\/\/doi.org\/10.15386\/cjmed-1030.","journal-title":"Med Pharm Reports"},{"issue":"1","key":"4352_CR4","first-page":"54","volume":"94","author":"AO Adisa","year":"2017","unstructured":"Adisa AO, Udeabor SE, Adeyemi BF, Akinyamoju AO, Ogun GO. Kimura\u2019s disease in a Nigerian: case report. East Afr Med J. 2017;94(1):54\u20139.","journal-title":"East Afr Med J"},{"issue":"2","key":"4352_CR5","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.anorl.2016.12.001","volume":"134","author":"M Drouillard","year":"2017","unstructured":"Drouillard M, Steve M, Ranoarivony T, Souraud JB. Kimura\u2019s disease in a 50-year-old Tunisian man. Eur Ann Otorhinolaryngol Head Neck Dis. 2017;134(2):127\u20139. https:\/\/doi.org\/10.1016\/j.anorl.2016.12.001.","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04352-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-024-04352-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04352-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T01:03:24Z","timestamp":1707181404000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-024-04352-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,6]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4352"],"URL":"https:\/\/doi.org\/10.1186\/s13256-024-04352-2","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,6]]},"assertion":[{"value":"25 March 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The patient had given written informed consent for the publication of the case report.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"44"}}