{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:14:42Z","timestamp":1740147282355,"version":"3.37.3"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T00:00:00Z","timestamp":1709856000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Complex regional pain syndrome type I is a pathological condition characterized by an exaggerated response of tissues to low or moderate pain stimuli. The exact pathogenesis and optimal medical treatment for complex regional pain syndrome type I are still not fully understood, although bisphosphonates have shown positive effects in reducing pain. Foot surgery can be complicated by the development of complex regional pain syndrome type I, leading to functional decline and difficulties in weight-bearing.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>The authors present a clinical case involving complex regional pain syndrome type I that developed after surgical foot arthrodesis. The patient, a 42-year-old Caucasian male, did not respond to clodronate treatment but experienced successful outcomes upon the addition of teriparatide, which effectively stimulated the healing of arthrodesis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Teriparatide cannot be considered the primary treatment for complex regional pain syndrome due to insufficient solid clinical data. However, when complex regional pain syndrome is associated with or caused by delayed union, teriparatide can be used to address the underlying cause of complex regional pain syndrome.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04391-9","type":"journal-article","created":{"date-parts":[[2024,3,8]],"date-time":"2024-03-08T01:02:12Z","timestamp":1709859732000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Teriparatide and clodronate combination as a potential treatment for complex regional pain syndrome type I in delayed consolidation after foot surgery: a case report and review of the\u00a0literature"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1515-1701","authenticated-orcid":false,"given":"F.","family":"Di Sacco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Antognetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Ciapini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Nicastro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Scaglione","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Bottai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,8]]},"reference":[{"issue":"2","key":"4391_CR1","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1007\/s40122-021-00279-4","volume":"10","author":"SS Taylor","year":"2021","unstructured":"Taylor SS, Noor N, Urits I, et\u00a0al. Complex regional pain syndrome: a comprehensive review. Pain Ther. 2021;10(2):875\u201392. https:\/\/doi.org\/10.1007\/s40122-021-00279-4.","journal-title":"Pain Ther"},{"issue":"5","key":"4391_CR2","doi-asserted-by":"publisher","first-page":"434","DOI":"10.7417\/CT.2022.2459","volume":"173","author":"L Molfetta","year":"2022","unstructured":"Molfetta L, Florian A, Saviola G, Frediani B. Bone Marrow Edema: pathogenetic features. Clin Ter. 2022;173(5):434\u20139. https:\/\/doi.org\/10.7417\/CT.2022.2459.","journal-title":"Clin Ter"},{"issue":"2","key":"4391_CR3","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1007\/s40122-021-00279-4","volume":"53","author":"SS Taylor","year":"2021","unstructured":"Taylor SS, Noor N, Urits I, et\u00a0al. Complex regional pain syndrome, current concepts and treatment options. Curr Pain Headache Rep. 2021;53(2):2453\u20139. https:\/\/doi.org\/10.1007\/s40122-021-00279-4.","journal-title":"Curr Pain Headache Rep"},{"issue":"2","key":"4391_CR4","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.pain.2010.04.030","volume":"150","author":"RN Harden","year":"2010","unstructured":"Harden RN, Bruehl S, Perez RSGM, et\u00a0al. Validation of proposed diagnostic criteria (the \u00abbudapest Criteria\u00bb) for complex regional pain syndrome. Pain. 2010;150(2):268\u201374. https:\/\/doi.org\/10.1016\/j.pain.2010.04.030.","journal-title":"Pain"},{"issue":"6","key":"4391_CR5","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1093\/pm\/pnw207","volume":"18","author":"M Varenna","year":"2017","unstructured":"Varenna M, Manara M, Rovelli F, Zucchi F, Sinigaglia L. Predictors of responsiveness to bisphosphonate treatment in patients with complex regional pain syndrome type I: a retrospective chart analysis. Pain Med. 2017;18(6):1131\u20138. https:\/\/doi.org\/10.1093\/pm\/pnw207.","journal-title":"Pain Med"},{"issue":"2","key":"4391_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2023.03.006","volume":"26","author":"S Li","year":"2023","unstructured":"Li S, Yu H, Long S, et\u00a0al. Research advances in the treatment of bone marrow edema syndrome. J Clin Densitom. 2023;26(2): 101367. https:\/\/doi.org\/10.1016\/j.jocd.2023.03.006.","journal-title":"J Clin Densitom"},{"key":"4391_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9020551","author":"SF Baumbach","year":"2020","unstructured":"Baumbach SF, Pfahler V, Pozza SBD, et\u00a0al. How we manage bone marrow edema\u2014an interdisciplinary approach. J Clin Med. 2020. https:\/\/doi.org\/10.3390\/jcm9020551.","journal-title":"J Clin Med"},{"issue":"8","key":"4391_CR8","doi-asserted-by":"publisher","first-page":"2395","DOI":"10.1007\/s00198-016-3534-6","volume":"27","author":"R Lindsay","year":"2016","unstructured":"Lindsay R, Krege JH, Marin F, Jin L, Stepan JJ. Teriparatide for osteoporosis: Importance of the full course. Osteoporos Int. 2016;27(8):2395\u2013410. https:\/\/doi.org\/10.1007\/s00198-016-3534-6.","journal-title":"Osteoporos Int"},{"issue":"1","key":"4391_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12891-023-06278-0","volume":"24","author":"G Gariffo","year":"2023","unstructured":"Gariffo G, Bottai V, Falcinelli F, et\u00a0al. Use of Teriparatide in preventing delayed bone healing and nonunion: a multicentric study on a series of 20 patients. BMC Musculoskelet Disord. 2023;24(1):1\u201310. https:\/\/doi.org\/10.1186\/s12891-023-06278-0.","journal-title":"BMC Musculoskelet Disord"},{"key":"4391_CR10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.37478","author":"CS Puvvada","year":"2023","unstructured":"Puvvada CS, Soomro FH, Osman HA, Haridi M, Gonzalez NA. Efficacy and safety of teriparatide in improving fracture healing and callus formation\u202f: a systematic review. Cureus. 2023. https:\/\/doi.org\/10.7759\/cureus.37478.","journal-title":"Cureus"},{"issue":"3","key":"4391_CR11","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1053\/j.jfas.2014.01.006","volume":"53","author":"MJ Rewhorn","year":"2014","unstructured":"Rewhorn MJ, Leung AH, Gillespie A, Moir JS, Miller R. Incidence of complex regional pain syndrome after foot and ankle surgery. 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