{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:01:30Z","timestamp":1776769290045,"version":"3.51.2"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,7]],"date-time":"2024-04-07T00:00:00Z","timestamp":1712448000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,7]],"date-time":"2024-04-07T00:00:00Z","timestamp":1712448000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Graves\u2019 disease is the autoimmune activation of the thyroid gland causing diffuse enlargement and hyperfunction of the gland. Manifestations of Graves\u2019 disease are multisystemic and include thyroid orbitopathy; pretibial myxedema, also referred to as thyroid dermopathy; and thyroid acropachy, described as a severe form of thyroid dermopathy. Our paper focuses on an atypical case of thyroid dermopathy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>An 11-year-old Saudi male presented with a prominent diffuse goiter and exophthalmos. Investigations were consistent with a diagnosis of Graves\u2019 disease. The physical exam showed diffuse, non-pitting swelling of the ankle and penis, mimicking a lymphatic malformation. Further, multiple nodules were found on the hands and feet. Treatment of the nodules with cautery resulted in more severe nodules.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This report describes rare presentations of thyroid dermopathy mimicking lymphatic malformation. The Koebner phenomenon can explain this patient\u2019s atypical presentations. Intralesional injections of triamcinolone and total thyroidectomy showed clear improvement.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04462-x","type":"journal-article","created":{"date-parts":[[2024,4,7]],"date-time":"2024-04-07T00:02:04Z","timestamp":1712448124000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Graves\u2019 disease thyroid dermopathy: a case report"],"prefix":"10.1186","volume":"18","author":[{"given":"Loay","family":"Tashkandi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1844-4377","authenticated-orcid":false,"given":"Afaf","family":"Alsagheir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saud","family":"Alobaida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghad","family":"Alhuthil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,7]]},"reference":[{"issue":"4","key":"4462_CR1","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/j.beem.2011.10.001","volume":"26","author":"V Fatourechi","year":"2012","unstructured":"Fatourechi V. Thyroid dermopathy and acropachy. Best Pract Res Clin Endocrinol Metab. 2012;26(4):553\u201365.","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"6","key":"4462_CR2","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13670","volume":"35","author":"CN Kraus","year":"2018","unstructured":"Kraus CN, Sodha P, Vaidyanathan P, Kirkorian AY. Thyroid dermopathy and acropachy in pediatric patients. Pediatric Dermatol. 2018;35(6): e371.","journal-title":"Pediatric Dermatol"},{"key":"4462_CR3","unstructured":"Sanchez DP, Sonthalia S. Koebner phenomenon. U.S. National Library of Medicine; 2023. https:\/\/pubmed.ncbi.nlm.nih.gov\/31971748\/#:~:text=The%20Koebner%20phenomenon%20(KP)%2C,unaffected%20skin%20secondary%20to%20trauma. Accessed 10 May 2023."},{"issue":"5","key":"4462_CR4","doi-asserted-by":"publisher","first-page":"295","DOI":"10.2165\/00128071-200506050-00003","volume":"6","author":"V Fatourechi","year":"2005","unstructured":"Fatourechi V. Pretibial myxedema. Am J Clin Dermatol. 2005;6(5):295\u2013309.","journal-title":"Am J Clin Dermatol"},{"issue":"6","key":"4462_CR5","first-page":"302","volume":"58","author":"UH Malabu","year":"2008","unstructured":"Malabu UH, Alfadda A, Sulimani RA, Al-Rubeaan KA, Al-Ruhaily AD, Fouda MA, Al-Maatouq MA, El-Desouki MI. Graves\u2019 disease in Saudi Arabia: a ten-year hospital study. J Pak Med Assoc. 2008;58(6):302\u20134.","journal-title":"J Pak Med Assoc"},{"key":"4462_CR6","unstructured":"LaFranchi S. Clinical manifestations and diagnosis of Graves disease in children and adolescents. In: UptoDate. UptoDate; 2021."}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04462-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-024-04462-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04462-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,7]],"date-time":"2024-04-07T00:02:23Z","timestamp":1712448143000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-024-04462-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,7]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4462"],"URL":"https:\/\/doi.org\/10.1186\/s13256-024-04462-x","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,7]]},"assertion":[{"value":"27 May 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was cleared for publication by the institutional review board in King Faisal Specialist Hospital and Research Centre (KFSHRC; reference: 2235180). Informed consent was obtained from the patient\u2019s legal guardian in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s legal guardian for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors state that they do not have any competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"164"}}