{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T21:57:34Z","timestamp":1791496654331,"version":"4.3.4"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T00:00:00Z","timestamp":1711324800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T00:00:00Z","timestamp":1711324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p><jats:italic>Stenotrophomonas maltophilia<\/jats:italic> is a gram-negative bacteria known for causing opportunistic and nosocomial infections in humans. <jats:italic>S. maltophilia<\/jats:italic> is an emerging pathogen of concern due to it\u2019s increasing prevalence, diverse disease spectrum, intrinsic multi-drug resistance and high mortality rates in immunocompromised individuals. S. <jats:italic>maltophilia<\/jats:italic> is a rare cause of neonatal sepsis associated with significant morbidity and mortality. The bacterium\u2019s multi-drug resistance poses a considerable challenge for treatment, with various mechanisms contributing to its resistance.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We report a case involving a 40-h-old male African neonate who exhibited symptoms of neonatal sepsis. The blood culture revealed <jats:italic>Stenotrophomonas maltophilia<\/jats:italic>, which was sensitive to ciprofloxacin and gentamicin but resistant to other antibiotics. Lumbar puncture for CSF could not be done because the father declined.<\/jats:p>\n                <jats:p>We treated the newborn with the empirical first-line antibiotics as per the national guideline intravenous ampicillin and gentamicin for six days, and the child recovered fully with a repeated negative blood culture.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This report describes a neonatal sepsis case caused by <jats:italic>S. maltophilia,<\/jats:italic> a multi-drug resistant bacteria and a rare cause of neonatal sepsis. We report that early detection of the bacterial and antimicrobial management based on local antibiogram data may be essential for successful patient\u2019s management.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04479-2","type":"journal-article","created":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T02:32:08Z","timestamp":1711333928000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Stenotrophomonas maltophilia neonatal sepsis: a case report"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1928-4862","authenticated-orcid":false,"given":"Williams Oluwatosin","family":"Adefila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Osie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Modou Lamin","family":"Keita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baleng Mahama","family":"Wutor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulsalam Olawale","family":"Yusuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilias","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minteh","family":"Molfa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ousman","family":"Barjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasheed","family":"Salaudeen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Mackenzie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,25]]},"reference":[{"issue":"2018","key":"4479_CR1","first-page":"1543934","volume":"13","author":"J Ibrahim","year":"2018","unstructured":"Ibrahim J, Hamwi N, Rabei H, Abdelghafar M, Al-Dulaimi Z, Al TH. Stenotrophomonas maltophilia meningitis in a term healthy neonate: a case report and literature review. Case Rep Pediatr. 2018;13(2018):1543934.","journal-title":"Case Rep Pediatr"},{"issue":"6","key":"4479_CR2","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.3390\/diagnostics13061106","volume":"13","author":"G Dimopoulos","year":"2023","unstructured":"Dimopoulos G, Garnacho-Montero J, Paramythiotou E, Gutierrez-Pizarraya A, Gogos C, Adriansen-P\u00e9rez M, et al. Upraising Stenotrophomonas maltophilia in critically ill patients: a new enemy? Diagnostics. 2023;13(6):1106.","journal-title":"Diagnostics"},{"issue":"1","key":"4479_CR3","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3390\/microorganisms9010049","volume":"9","author":"A Pompilio","year":"2020","unstructured":"Pompilio A, Ranalli M, Piccirilli A, Perilli M, Vukovic D, Savic B, et al. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests\" in this section.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"180"}}