{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:29:37Z","timestamp":1775694577768,"version":"3.50.1"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>We present a severe neonatal consequence due to the unexpected and crucial inversion of the fetal position after sudden termination of tocolysis during early labor of a woman with congenital uterine anomaly. It has been reported that congenital uterine anomalies latently affect the fetal position. The clinical pitfalls in childbirth with uterine anomalies are discussed here on the basis of clinical evidence.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>At a perinatal medical center in Japan, a 29-year-old Japanese mother who had a history of bicornuate uterus, received tocolysis to prolong her pregnancy for 5\u00a0days during the late preterm period after preterm-premature rupture of the membrane. She gave birth to a 2304\u00a0g male neonate of the gestational age of 35\u00a0weeks and 5\u00a0days with severe asphyxia by means of crash cesarean section for fetal sustained bradycardia after sudden termination of tocolysis. We found the fetal position to reverse from cephalic to breech position during early labor. He ended up having severe cerebral palsy after brain cooling against hypoxic-ischemic encephalopathy for 3\u00a0days. The mechanism of inversion from cephalic to breech position without amnionic fluid remains unclear, although women with a known diagnosis of a uterine anomaly have higher risk of adverse outcomes such as malpresentation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>When considering the clinical course of this case on the basis of the medical reports, we suspected that uterine anomalies and changes in intrauterine pressure could cause fetal malpresentation and adverse neonatal outcomes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04524-0","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:01:49Z","timestamp":1714089709000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An unusual case of severe asphyxia with the fetal position unexpectedly inverted in a malformed uterus: a case report"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3977-2679","authenticated-orcid":false,"given":"Jiro","family":"Abe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Nasu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayumu","family":"Noro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Tsubaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,26]]},"reference":[{"key":"4524_CR1","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1016\/S0015-0282(16)54741-4","volume":"56","author":"C Sim\u00f3n","year":"1991","unstructured":"Sim\u00f3n C, Martinez L, Pardo F, et\u00a0al. M\u00fcllerian defects in women with normal reproductive outcome. Fertil Steril. 1991;56:1192\u20133.","journal-title":"Fertil Steril"},{"key":"4524_CR2","doi-asserted-by":"publisher","first-page":"1522","DOI":"10.1038\/s41372-021-00987-x","volume":"41","author":"P Chansarn","year":"2021","unstructured":"Chansarn P, Torgalkar R, Wilson D, Fan CPS, Widjaja E, Whyte H, Tam WYE, Lee KS. Correlation of Thompson and modified Sarnat scores in neonatal hypoxic ischemic encephalopathy. J Perinatol. 2021;41:1522\u20133.","journal-title":"J Perinatol"},{"key":"4524_CR3","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1097\/OGX.0000000000000408","volume":"72","author":"SA Vaz","year":"2017","unstructured":"Vaz SA, Dotters-Katz SK, Kuller JA. Diagnosis and management of congenital uterine anomalies in pregnancy. Obstet Gynecol Surv. 2017;72:194\u2013201.","journal-title":"Obstet Gynecol Surv"},{"key":"4524_CR4","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1002\/uog.10056","volume":"38","author":"YY Chan","year":"2011","unstructured":"Chan YY, Jayaprakasan K, Tan A, et\u00a0al. Reproductive outcomes in women with congenital uterine anomalies: a systematic review. Ultrasound Obstet Gynecol. 2011;38:371\u201382.","journal-title":"Ultrasound Obstet Gynecol"},{"key":"4524_CR5","doi-asserted-by":"publisher","first-page":"558e1","DOI":"10.1016\/j.ajog.2011.07.022","volume":"205","author":"M Hua","year":"2011","unstructured":"Hua M, Odibo AO, Longman RE, et\u00a0al. Congenital uterine anomalies and adverse pregnancy outcomes. Am J Obstet Gynecol. 2011;205:558e1\u20135.","journal-title":"Am J Obstet Gynecol."},{"key":"4524_CR6","first-page":"270","volume":"61","author":"H Cui","year":"2016","unstructured":"Cui H, Chen Y, Li Q, et\u00a0al. Cesarean rate and risk factors for singleton breech presentation in China. J Reprod Med. 2016;61:270\u20134.","journal-title":"J Reprod Med"},{"key":"4524_CR7","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1542\/peds.2013-1131","volume":"132","author":"A Kugelman","year":"2013","unstructured":"Kugelman A, Colin AA. Late preterm infants: near term but still in a critical developmental time period. Pediatrics. 2013;132:741\u201351.","journal-title":"Pediatrics"},{"key":"4524_CR8","doi-asserted-by":"publisher","first-page":"2705","DOI":"10.1080\/14767058.2016.1261396","volume":"30","author":"SA Mastrolia","year":"2017","unstructured":"Mastrolia SA, Baumfeld Y, Hershkovitz R, Loverro G, Naro ED, Yohai D, Schwarzman P, Weintraub AY. Bicornuate uterus is an independent risk factor for cervical OS insufficiency: a retrospective population based cohort study. Matern Fetal Neonatal Med. 2017;30:2705\u201310.","journal-title":"Matern Fetal Neonatal Med"},{"key":"4524_CR9","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/j.gyobfe.2014.05.003","volume":"42","author":"E Guinard","year":"2014","unstructured":"Guinard E, Subtil D, Deruelle P. Congenital m\u00fcllerian anomalies and delivery: analysis of 304 cases between 2000 and 2010 at the university hospital of Lille [in French]. Gynecol Obstet Fertil. 2014;42:471\u20136.","journal-title":"Gynecol Obstet Fertil"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04524-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-024-04524-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04524-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:01:54Z","timestamp":1714089714000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-024-04524-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,26]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4524"],"URL":"https:\/\/doi.org\/10.1186\/s13256-024-04524-0","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,26]]},"assertion":[{"value":"1 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"We strictly followed the rules for publication by the research ethics committee in Hokkaido University Hospital, which permitted us to participate.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"We have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"209"}}