{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:04:42Z","timestamp":1793135082922,"version":"4.5.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T00:00:00Z","timestamp":1717804800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T00:00:00Z","timestamp":1717804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>To report a case of Multiple Evanescent White Dot Syndrome (MEWDS) one month after a COVID-19 infection in a female patient at an age unusual for the occurrence of this disease.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 69-year-old Caucasian female reported the presence of floaters, photopsia, and enlarging vision loss in her left eye following the COVID-19 infection. Clinical and multimodal imaging was consistent with the MEWDS diagnosis. Fluorescein angiography examination revealed characteristic hyperfluorescent spots around the fovea in a wreath-like pattern. An extensive lab workup to rule out other autoimmune and infectious etiologies was inconclusive. Visual acuity and white dots resolved after a course of corticosteroids, which was confirmed on follow-up dilated fundus exam and multimodal imaging.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>MEWDS is a rare white dot syndrome that may occur following COVID-19 infection in addition to other reported ophthalmic disorders following this infection.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04596-y","type":"journal-article","created":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T00:01:44Z","timestamp":1717804904000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Multiple evanescent white dot syndrome associated with COVID-19 infection: a case report"],"prefix":"10.1186","volume":"18","author":[{"given":"Michael","family":"Ting","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Hsueh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jila","family":"Noori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,8]]},"reference":[{"issue":"1","key":"4596_CR1","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1186\/s12348-021-00279-7","volume":"11","author":"I Papasavvas","year":"2021","unstructured":"Papasavvas I, Mantovani A, Tugal-Tutkun I, Herbort CPJ. Multiple evanescent white dot syndrome (MEWDS): update on practical appraisal, diagnosis, and clinicopathology; a review and an alternative comprehensive perspective. J Ophthalmic Inflamm Infect. 2021;11(1):45.","journal-title":"J Ophthalmic Inflamm Infect"},{"issue":"4","key":"4596_CR2","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1097\/IIO.0b013e31826647ed","volume":"52","author":"R dell\u2019Omo","year":"2012","unstructured":"dell\u2019Omo R, Pavesio CE. Multiple evanescent white dot syndrome (MEWDS). Int Ophthalmol Clin. 2012;52(4):221\u20138.","journal-title":"Int Ophthalmol Clin"},{"issue":"2","key":"4596_CR3","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000028582","volume":"101","author":"S Inagawa","year":"2022","unstructured":"Inagawa S, Onda M, Miyase T, et al. Multiple evanescent white dot syndrome following vaccination for COVID-19: a case report. Medicine. 2022;101(2): e28582.","journal-title":"Medicine"},{"issue":"2","key":"4596_CR4","doi-asserted-by":"publisher","first-page":"186","DOI":"10.5935\/0004-2749.20220016","volume":"85","author":"KS Tomishige","year":"2022","unstructured":"Tomishige KS, Novais EA, Finamor LPDS, Nascimento HMD, Belfort R Jr. Multiple evanescent white dot syndrome (MEWDS) following inactivated COVID-19 vaccination (Sinovac-CoronaVac). Arq Bras Oftalmol. 2022;85(2):186\u20139.","journal-title":"Arq Bras Oftalmol"},{"key":"4596_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajoc.2022.101532","volume":"26","author":"E Yasuda","year":"2022","unstructured":"Yasuda E, Matsumiya W, Maeda Y, et al. Multiple evanescent white dot syndrome following BNT162b2 mRNA COVID-19 vaccination. 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Vaccines. 2022;10(11):1776.","journal-title":"Vaccines"},{"key":"4596_CR8","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.2147\/OPTH.S301040","volume":"15","author":"Y Feng","year":"2021","unstructured":"Feng Y, Park J, Zhou Y, Armenti ST, Musch DC, Mian SI. Ocular manifestations of hospitalized COVID-19 patients in a tertiary care academic medical center in the United States: a cross-sectional study. Clin Ophthalmol. 2021;15:1551\u20136.","journal-title":"Clin Ophthalmol"},{"issue":"3","key":"4596_CR9","doi-asserted-by":"publisher","first-page":"488","DOI":"10.4103\/ijo.IJO_297_21","volume":"69","author":"M Sen","year":"2021","unstructured":"Sen M, Honavar SG, Sharma N, Sachdev MS. COVID-19 and eye: a review of ophthalmic manifestations of COVID-19. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publications"}},{"value":"The following authors have nothing to disclose: MT, JH, and JL.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"272"}}