{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:34:47Z","timestamp":1776321287555,"version":"3.50.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:00:00Z","timestamp":1718755200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:00:00Z","timestamp":1718755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Schistosomiasis is one of the endemic parasitic diseases in many developing countries. Despite this, appendicitis secondary to schistosomiasis is an uncommon condition even in some endemic areas. Schistosomal appendicitis, an incidentally discovered appendicitis associated with schistosomiasis histological findings, affects young males predominantly. Timely diagnosis and treatment, including appendectomy and anti-helminthic therapy, are crucial.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case report<\/jats:title>\n                <jats:p>A 24-year-old Sudanese male patient presented with abdominal pain. Diagnosed with acute appendicitis, he underwent appendectomy, revealing appendix inflammation with <jats:italic>Schistosoma<\/jats:italic> ova in histopathology. Abdominal ultrasound detected no complications. Weakly positive <jats:italic>Schistosoma<\/jats:italic> serology was noted, but stool and urine analysis showed no infection evidence. Prescribed praziquantel, patient had 3-year post-op follow-up without complications.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This case report underscores the significance of including schistosomiasis in the differential diagnosis of appendicitis, particularly in regions where the disease is endemic. It underscores the necessity of histopathological evaluations for accurate diagnosis, emphasizing the potential implications for clinical practice in similar settings.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04610-3","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:02:01Z","timestamp":1718755321000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Schistosomal appendicitis: a case report"],"prefix":"10.1186","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0806-7741","authenticated-orcid":false,"given":"Mohanad","family":"Khalifa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman","family":"Elhassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sawsan","family":"Abdel Rahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"4610_CR1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjad188","author":"JX Li","year":"2023","unstructured":"Li JX, Fan HS. Schistosomal appendicitis: a rare cause of a common surgical condition. J Surg Case Rep. 2023. https:\/\/doi.org\/10.1093\/jscr\/rjad188.","journal-title":"J Surg Case Rep"},{"key":"4610_CR2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009478","volume":"15","author":"M Zacarias","year":"2021","unstructured":"Zacarias M, Pizzol D, de Miranda H, Colangelo AC, Veronese N, Smith L. Schistosomal appendicitis: case series and systematic literature review. PLoS Negl Trop Dis. 2021;15: e0009478.","journal-title":"PLoS Negl Trop Dis"},{"key":"4610_CR3","doi-asserted-by":"publisher","DOI":"10.1186\/S40792-019-0615-8","author":"H Imamura","year":"2019","unstructured":"Imamura H, Haraguchi M, Isagawa Y, Morita M, Hirabaru M, Kawahara D, Tokai H, Noda K, Minami S, Inoue K, Irie J. Acute appendicitis associated with the presence of schistosome eggs in a sailor: a case report. 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BMC Med. 2011;9:139. https:\/\/doi.org\/10.1186\/1741-7015-9-139.","journal-title":"BMC Med."},{"key":"4610_CR6","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1177\/000313480807400308","volume":"74","author":"K Nandipati","year":"2008","unstructured":"Nandipati K, Parithivel V, Niazi M. Schistosomiasis: a rare cause of acute appendicitis in the African American population in the United States. Am Surg. 2008;74:221\u20133.","journal-title":"Am Surg"},{"issue":"1","key":"4610_CR7","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1186\/s13071-019-3689-z","volume":"12","author":"S Cha","year":"2019","unstructured":"Cha S, Elhag MS, Lee YH, et al. Epidemiological findings and policy implications from the nationwide schistosomiasis and intestinal helminthiasis survey in Sudan. Parasit Vectors. 2019;12(1):429. https:\/\/doi.org\/10.1186\/s13071-019-3689-z.","journal-title":"Parasit Vectors"},{"issue":"4","key":"4610_CR8","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12970","volume":"45","author":"KA Stark","year":"2023","unstructured":"Stark KA, Rinaldi G, Cort\u00e9s A, Costain A, MacDonald AS, Cantacessi C. The role of the host gut microbiome in the pathophysiology of schistosomiasis. Parasite Immunol. 2023;45(4): e12970. https:\/\/doi.org\/10.1111\/pim.12970.","journal-title":"Parasite Immunol."},{"issue":"10139","key":"4610_CR9","doi-asserted-by":"publisher","first-page":"2546","DOI":"10.1016\/S0140-6736(18)31329-1","volume":"391","author":"C Kraef","year":"2018","unstructured":"Kraef C, Arand J, Veletzky L, Schafer H, Jordan S, Schmiedel S, et al. Schistosomiasis detected during appendectomy. 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Front Pharmacol. 2023. https:\/\/doi.org\/10.3389\/fphar.2023.968106.","journal-title":"Front Pharmacol"},{"key":"4610_CR14","doi-asserted-by":"publisher","DOI":"10.34172\/ijmpes.2023.07","author":"P Bour\u00e9e","year":"2023","unstructured":"Bour\u00e9e P, Garedaghi Y, Ensaf A, Bisaro F, Salmon D. A case report of an appendicitis and parasitosis. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None declared.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"283"}}