{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T16:26:06Z","timestamp":1764433566916},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>We present a unique case of rhinolalia as the first recognizable sign of spontaneous pneumomediastinum and surgical emphysema following drug use.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>This case presents a 17-year-old white male experiencing rhinolalia following ecstasy ingestion at a rave. Subsequent chest X-ray revealed extensive surgical emphysema, along with a continuous diaphragm sign indicative of pneumomediastinum. Computed tomography confirmed the diagnosis. The patient was managed conservatively with strict monitoring and 6 hourly electrocardiograms. Follow-up computed tomography on day 3 showed resolution of pneumomediastinum and surgical emphysema, and the patient was safely discharged. Notably, the patient experienced a temporary rhinolalia during the acute phase, which resolved spontaneously as his condition improved.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This case underscores the importance of considering spontaneous pneumomediastinum and surgical emphysema in the differential diagnosis of young individuals presenting with acute symptoms after drug use.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04618-9","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:02:19Z","timestamp":1719532939000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Spontaneous pneumomediastinum and surgical emphysema presenting as rhinolalia following ecstasy ingestion: a case report"],"prefix":"10.1186","volume":"18","author":[{"given":"Caterina","family":"Prada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"issue":"11","key":"4618_CR1","first-page":"966","volume":"61","author":"S Bernschneider-Reif","year":"2006","unstructured":"Bernschneider-Reif S, Oxler F, Freudenmann RW. The origin of MDMA (\u201cecstasy\u201d)\u2014separating the facts from the myth. Pharmazie. 2006;61(11):966\u201372.","journal-title":"Pharmazie"},{"issue":"3","key":"4618_CR2","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.rmedx.2005.04.006","volume":"1","author":"S Burghart","year":"2005","unstructured":"Burghart S, Armbruster C. Ecstasy induced pneumomediastinum and pneumothorax\u2014new causes, new questions. Respir Med Extra. 2005;1(3):53\u20135. https:\/\/doi.org\/10.1016\/j.rmedx.2005.04.006.","journal-title":"Respir Med Extra"},{"key":"4618_CR3","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-223103","author":"NE Obiechina","year":"2018","unstructured":"Obiechina NE, et al. Bilateral pneumothorax, surgical emphysema and pneumomediastinum in a young male patient following MDMA intake. BMJ Case Rep. 2018. https:\/\/doi.org\/10.1136\/bcr-2017-223103.","journal-title":"BMJ Case Rep"},{"issue":"4","key":"4618_CR4","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.rmedc.2011.03.005","volume":"4","author":"J Meireles","year":"2011","unstructured":"Meireles J, et al. Spontaneous pneumomediastinum revisited. Respir Med CME. 2011;4(4):181\u20133. https:\/\/doi.org\/10.1016\/j.rmedc.2011.03.005.","journal-title":"Respir Med CME"},{"issue":"5","key":"4618_CR5","doi-asserted-by":"publisher","first-page":"3298","DOI":"10.1378\/chest.128.5.3298","volume":"128","author":"AE Newcomb","year":"2005","unstructured":"Newcomb AE, Clarke CP. Spontaneous pneumomediastinum. Chest. 2005;128(5):3298\u2013302. https:\/\/doi.org\/10.1378\/chest.128.5.3298.","journal-title":"Chest"},{"key":"4618_CR6","first-page":"1","volume":"64","author":"L Hamman","year":"1939","unstructured":"Hamman L. Spontaneous mediastinal emphysema. Bull Johns Hopkins Hosp. 1939;64:1\u201321.","journal-title":"Bull Johns Hopkins Hosp"},{"issue":"3","key":"4618_CR7","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1016\/j.athoracsur.2008.04.067","volume":"86","author":"M Caceres","year":"2008","unstructured":"Caceres M, et al. Spontaneous pneumomediastinum: a comparative study and review of the literature. Ann Thorac Surg. 2008;86(3):962\u20136. https:\/\/doi.org\/10.1016\/j.athoracsur.2008.04.067.","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"4618_CR8","doi-asserted-by":"publisher","first-page":"287","DOI":"10.5090\/kjtcs.2016.49.4.287","volume":"49","author":"SJ Park","year":"2016","unstructured":"Park SJ, et al. Clinical manifestations of spontaneous pneumomediastinum. Korean J Thorac Cardiovasc Surg. 2016;49(4):287\u201391. https:\/\/doi.org\/10.5090\/kjtcs.2016.49.4.287.","journal-title":"Korean J Thorac Cardiovasc Surg"},{"issue":"4","key":"4618_CR9","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1308\/003588407x183373","volume":"89","author":"SF Marasco","year":"2007","unstructured":"Marasco SF, Lim HK. Ecstasy-associated pneumomediastinum. Ann R Coll Surg Engl. 2007;89(4):389\u201393. https:\/\/doi.org\/10.1308\/003588407x183373.","journal-title":"Ann R Coll Surg Engl"},{"issue":"4","key":"4618_CR10","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1016\/s0194-5998(97)70310-3","volume":"116","author":"I Braverman","year":"1997","unstructured":"Braverman I, Rosenmann E, Elidan J. Closed rhinolalia as a symptom of pneumomediastinum after tonsillectomy: a case report and literature review. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no conflicting\/competing interests to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"306"}}