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Here we present a case of a 63-year-old man with coronavirus disease 2019 infection, along with rhinosinusitis mucormycosis caused by <jats:italic>Rhizopus delemar<\/jats:italic>.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 63-year-old Iranian man suffering from a coronavirus disease 2019 infection with symptoms of cough, shortness of breath, and generalized body pain. On the basis of the clinical manifestations, such as headache, a history of black nasal discharge, nasal hypoesthesia, facial swelling, numbness, nasal obstruction, presence of necrotic lesions on the nasal passages on physical examination, and abnormal computed tomography scans of paranasal sinuses, the patient underwent surgical debridement. Direct microscopy of specimens obtained from the paranasal sinuses, and subsequent isolation and identification, revealed a rhinosinusitis mucormycosis caused by <jats:italic>R<\/jats:italic>. <jats:italic>delemar<\/jats:italic>. Despite therapeutic measures, such as sinus debridement surgery and antifungal therapy with amphotericin B injection (50 mg\/day), the patient died after 35\u00a0days of hospitalization.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In this report, we present the first documented case of human infection with <jats:italic>R<\/jats:italic>. <jats:italic>delemar<\/jats:italic> in a patient with coronavirus disease 2019 infection, who also exhibited rhinosinusitis mucormycosis. <jats:italic>R<\/jats:italic>. <jats:italic>delemar<\/jats:italic> appears to be an emerging agent of rhinosinusitis mucormycosis in this region. Furthermore, prompt diagnosis and the exploration of alternative antifungal treatments, beyond amphotericin B, may be crucial for effectively managing patients with <jats:italic>R<\/jats:italic>. <jats:italic>delemar<\/jats:italic> infections.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04873-w","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T01:02:29Z","timestamp":1730768549000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The first report of rhinosinusitis by Rhizopus delemar in a patient with severe COVID-19 in Iran: a case report"],"prefix":"10.1186","volume":"18","author":[{"given":"Seyedeh Sabereh","family":"Mojtahedi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neginsadat","family":"Hosseinikargar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Zarrinfar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Bakhshaee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Javad","family":"Najafzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya Bin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos","family":"Houbraken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,11,5]]},"reference":[{"issue":"2","key":"4873_CR1","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.mycmed.2018.02.014","volume":"28","author":"S Dolatabadi","year":"2018","unstructured":"Dolatabadi S, Ahmadi B, Rezaei-Matehkolaei A, Zarrinfar H, Skiada A, Mirhendi H, Nashibi R, Niknejad F, Nazeri M, Rafiei A. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"522"}}