{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:42:54Z","timestamp":1788997374630,"version":"build-2803163510"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Traditional Chinese Medicine Health Science and Technology Plan Project of\u00a0Zhejiang Province","award":["2022ZA184"],"award-info":[{"award-number":["2022ZA184"]}]},{"DOI":"10.13039\/501100018552","name":"Science and Technology Plan Project of Taizhou","doi-asserted-by":"publisher","award":["22ywb54"],"award-info":[{"award-number":["22ywb54"]}],"id":[{"id":"10.13039\/501100018552","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Cavernous hemangioma is a congenital insidious disease that can occur in any part of the central nervous system. In clinical practice, cavernous hemangioma is mostly found in the brain and rarely in the spinal cord.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case summary<\/jats:title>\n                <jats:p>This study describes a case of a 34-year-old Chinese man of Han ethnicity with lumbar intramedullary cavernous hemangioma. On admission, lumbar intramedullary hemorrhage was observed in the patient, as well as a spindle-shaped hematoma sign was detected on the spinal magnetic resonance imaging. We suspected that the spinal hemorrhage could be associated with spinal cord cavernous hemangioma. The patient was started on dehydration and glucocorticoid therapy of mannitol on the day of admission and was diagnosed with cavernous hemangioma on the basis of his magnetic resonance imaging presentation and spinal cord histopathology results. However, there was no significant improvement in clinical manifestations following conservative treatment. It was exciting that the patient\u2019s condition improved after\u00a0the surgical\u00a0removal of hematomas.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Clinicians should consider lumbar intramedullary cavernous hemangioma in the differential diagnosis of early spinal cord hemorrhage with a spindle-shaped hematoma sign on the spinal magnetic resonance imaging.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13256-024-04885-6","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:01:29Z","timestamp":1732060889000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Presentation of lumbar intramedullary cavernous hemangioma by spindle-shaped hematoma sign on the spinal MRI: a case report"],"prefix":"10.1186","volume":"18","author":[{"given":"Zhinan","family":"Ye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaiying","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,20]]},"reference":[{"key":"4885_CR1","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/B978-0-444-63640-9.00023-0","volume":"143","author":"HE Goldstein","year":"2017","unstructured":"Goldstein HE, Solomon RA. Epidemiology of cavernous malformations. Handb Clin Neurol. 2017;143:241\u20137.","journal-title":"Handb Clin Neurol"},{"key":"4885_CR2","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1227\/00006123-198602000-00008","volume":"18","author":"F Garcia-Bengochea","year":"1986","unstructured":"Garcia-Bengochea F, Simard JM, Ballinger WE Jr, Mickle JP, Quisling RG. Cavernous angioma: a review of 126 collected and 12 new clinical cases. Neurosurgery. 1986;18:162\u201372.","journal-title":"Neurosurgery"},{"key":"4885_CR3","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.jocn.2021.05.034","volume":"90","author":"G Qiao","year":"2021","unstructured":"Qiao G, Zhang L, Yu X, Shang A. Long-term surgical outcomes and prognostic factors of adult symptomatic spinal cord cavernous malformations. J Clin Neurosci. 2021;90:171\u20137.","journal-title":"J Clin Neurosci"},{"key":"4885_CR4","doi-asserted-by":"publisher","first-page":"271","DOI":"10.3171\/2019.1.SPINE18854","volume":"31","author":"N Nagoshi","year":"2019","unstructured":"Nagoshi N, Tsuji O, Nakashima D, Takeuchi A, Kameyama K, Okada E, Fujita N, Yagi M, Matsumoto M, Nakamura M, Watanabe K. Clinical outcomes and prognostic factors for cavernous hemangiomas of the spinal cord: a retrospective cohort study. J Neurosurg Spine. 2019;31:271\u20138.","journal-title":"J Neurosurg Spine"},{"key":"4885_CR5","doi-asserted-by":"publisher","first-page":"471","DOI":"10.2176\/nmc.43.471","volume":"43","author":"N Aoyagi","year":"2003","unstructured":"Aoyagi N, Kojima K, Kasai H. Review of spinal epidural cavernous hemangioma. Neurol Med Chir (Tokyo). 2003;43:471\u20136.","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"4885_CR6","doi-asserted-by":"publisher","first-page":"e105","DOI":"10.1016\/j.wneu.2018.06.134","volume":"118","author":"J Li","year":"2018","unstructured":"Li J, Chen G, Gu S, Liu X, Shou J, Gu W, Gao X, Xu Q, Che X, Xie R. Surgical outcomes of spinal cord intramedullary cavernous malformation: a retrospective study of 83 patients in a Single Center over a 12-year period. World Neurosurg. 2018;118:e105\u201314.","journal-title":"World Neurosurg"},{"key":"4885_CR7","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1136\/jnnp-2018-319553","volume":"90","author":"A Goyal","year":"2019","unstructured":"Goyal A, Rinaldo L, Alkhataybeh R, Kerezoudis P, Alvi MA, Flemming KD, Williams L, Diehn F, Bydon M. Clinical presentation, natural history and outcomes of intramedullary spinal cord cavernous malformations. J Neurol Neurosurg Psychiatry. 2019;90:695\u2013703.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"4885_CR8","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1111\/jon.12738","volume":"30","author":"A Panda","year":"2020","unstructured":"Panda A, Diehn FE, Kim DK, Bydon M, Goyal A, Benson JC, Carr CM, Rinaldo L, Flemming KD, Lanzino G. Spinal cord cavernous malformations: MRI commonly shows adjacent intramedullary hemorrhage. Neuroimaging. 2020;30:690\u20136.","journal-title":"Neuroimaging"},{"key":"4885_CR9","first-page":"1","volume":"17","author":"AN Santos","year":"2021","unstructured":"Santos AN, Rauschenbach L, Darkwah Oppong M, Gembruch O, Saban D, Chen B, Herten A, Schmidt B, Li Y, \u00d6zkan N, Jabbarli R, Wrede K, Sure U, Dammann P. Natural course of untreated spinal cord cavernous malformations: a follow-up study within the initial 5 years after diagnosis. J Neurosurg Spine. 2021;17:1\u20135.","journal-title":"J Neurosurg Spine"},{"key":"4885_CR10","doi-asserted-by":"publisher","first-page":"3119","DOI":"10.1007\/s00586-022-07332-6","volume":"31","author":"E Asimakidou","year":"2022","unstructured":"Asimakidou E, Meszaros LT, Anestis DM, Tsitsopoulos PP. A systematic review on the outcome of intramedullary spinal cord cavernous malformations. Eur Spine J. 2022;31:3119\u201329.","journal-title":"Eur Spine J."}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04885-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-024-04885-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04885-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T01:05:57Z","timestamp":1732064757000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-024-04885-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,20]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4885"],"URL":"https:\/\/doi.org\/10.1186\/s13256-024-04885-6","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,20]]},"assertion":[{"value":"4 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"555"}}