{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T02:24:20Z","timestamp":1783995860582,"version":"3.55.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"DOI":"10.1186\/s13256-024-04938-w","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T06:23:53Z","timestamp":1732861433000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An example of cytisine overdose with no consequent side-effects: a case report"],"prefix":"10.1186","volume":"18","author":[{"given":"Simone","family":"Campagnari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7189-7300","authenticated-orcid":false,"given":"Lorenzo","family":"Zamboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Barbon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Fusina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Lugoboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,29]]},"reference":[{"issue":"3","key":"4938_CR1","first-page":"205","volume":"3","author":"HH Dale","year":"1912","unstructured":"Dale HH, Laidlaw PP. The physiological action of cytisine, the active alkaloid of laburnum (cytisuslaburnum). J Pharmacol Exp Ther. 1912;3(3):205\u201321.","journal-title":"J Pharmacol Exp Ther"},{"issue":"1\u20133","key":"4938_CR2","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.forsciint.2009.01.011","volume":"186","author":"F Musshoff","year":"2009","unstructured":"Musshoff F, Madea B. Fatal cytisine intoxication and analysis of biological samples with LC-MS\/MS. Forensic Sci Int. 2009;186(1\u20133):e1-4.","journal-title":"Forensic Sci Int"},{"key":"4938_CR3","first-page":"10","volume":"5","author":"PP Laidlaw","year":"1912","unstructured":"Laidlaw PP. Laburnum poisoning and cytisine. Proc R Soc Med. 1912;5:10\u20138.","journal-title":"Proc R Soc Med"},{"key":"4938_CR4","doi-asserted-by":"publisher","first-page":"f5198","DOI":"10.1136\/bmj.f5198","volume":"347","author":"JJ Prochaska","year":"2013","unstructured":"Prochaska JJ, Das S, Benowitz NL. Cytisine, the world\u2019s oldest smoking cessation aid. BMJ. 2013;347:f5198.","journal-title":"BMJ"},{"issue":"11","key":"4938_CR5","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.1111\/add.14721","volume":"114","author":"P Tutka","year":"2019","unstructured":"Tutka P, Vinnikov D, Courtney RJ, Benowitz NL. Cytisine for nicotine addiction treatment: a review of pharmacology, therapeutics and an update of clinical trial evidence for smoking cessation. Addiction. 2019;114(11):1951\u201369.","journal-title":"Addiction"},{"issue":"10","key":"4938_CR6","doi-asserted-by":"publisher","first-page":"3474","DOI":"10.1021\/jm050069n","volume":"48","author":"JW Coe","year":"2005","unstructured":"Coe JW, Brooks PR, Vetelino MG, et\u00a0al. Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation. J Med Chem. 2005;48(10):3474\u20137.","journal-title":"J Med Chem"},{"issue":"6","key":"4938_CR7","first-page":"777","volume":"58","author":"P Tutka","year":"2006","unstructured":"Tutka P, Zato\u0144ski W. Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy. Pharmacol Rep. 2006;58(6):777\u201398.","journal-title":"Pharmacol Rep"},{"issue":"15","key":"4938_CR8","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.1001\/archinte.166.15.1553","volume":"166","author":"JF Etter","year":"2006","unstructured":"Etter JF. Cytisine for smoking cessation: a literature review and a meta-analysis. Arch Intern Med. 2006;166(15):1553\u20139.","journal-title":"Arch Intern Med"},{"issue":"11","key":"4938_CR9","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1111\/add.13464","volume":"111","author":"N Walker","year":"2016","unstructured":"Walker N, Bullen C, Barnes J, et\u00a0al. Getting cytisine licensed for use world-wide: a call to action. Addiction. 2016;111(11):1895\u20138. https:\/\/doi.org\/10.1111\/add.13464.","journal-title":"Addiction"},{"issue":"6672","key":"4938_CR10","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/s0140-6736(51)91315-3","volume":"2","author":"RG Mitchell","year":"1951","unstructured":"Mitchell RG. Laburnum poisoning in children; report on ten cases. Lancet. 1951;2(6672):57\u20138. https:\/\/doi.org\/10.1016\/s0140-6736(51)91315-3.","journal-title":"Lancet"},{"issue":"3","key":"4938_CR11","doi-asserted-by":"publisher","first-page":"e41","DOI":"10.1016\/j.jemermed.2017.04.033","volume":"53","author":"N Gim\u00e9nez","year":"2017","unstructured":"Gim\u00e9nez N, Magro N, Cort\u00e9s N, Guitart R. Poisoning after ingestion of Spartium junceum seeds: dose-dependent effects in three boys. J Emerg Med. 2017;53(3):e41\u20134.","journal-title":"J Emerg Med"},{"issue":"4","key":"4938_CR12","first-page":"369","volume":"55","author":"A Ariano","year":"2019","unstructured":"Ariano A, Costagliola A, D\u2019Ambola M, et\u00a0al. Spartium junceum L. poisoning in small ruminants. Vet Ital. 2019;55(4):369\u201373.","journal-title":"Vet Ital"},{"issue":"1","key":"4938_CR13","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1590\/S1806-37132009000100011","volume":"35","author":"IC Meneses-Gaya","year":"2009","unstructured":"Meneses-Gaya IC, Zuardi AW, Loureiro SR, Crippa JA. Psychometric properties of the Fagerstr\u00f6m Test for Nicotine Dependence. J Bras Pneumol. 2009;35(1):73\u201382.","journal-title":"J Bras Pneumol"},{"key":"4938_CR14","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/S0140-6736(79)92963-5","volume":"1","author":"RM Forrester","year":"1979","unstructured":"Forrester RM. Have you eaten laburnum? Lancet. 1979;1:1073.","journal-title":"Lancet"},{"key":"4938_CR15","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1177\/002580247001000417","volume":"10","author":"HG Richards","year":"1970","unstructured":"Richards HG, Stephens A. A fatal case of laburnum seed poisoning. Med Sci Law. 1970;10:260\u20136.","journal-title":"Med Sci Law"},{"key":"4938_CR16","first-page":"31","volume":"6","author":"S Stoyanov","year":"1972","unstructured":"Stoyanov S, Yanachkova M. Tabex\u2014therapeutic efficacy and tolerance. Savr Med XXIII. 1972;6:31\u20133.","journal-title":"Savr Med XXIII"},{"key":"4938_CR17","doi-asserted-by":"publisher","first-page":"1553","DOI":"10.1001\/archinte.166.15.1553","volume":"166","author":"JF Etter","year":"2006","unstructured":"Etter JF. Cytisine for smoking cessation, a literature review and a meta- analysis. Arch Intern Med. 2006;166:1553\u20139.","journal-title":"Arch Intern Med"},{"issue":"1-3","key":"4938_CR18","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.drugalcdep.2007.06.017","volume":"92","author":"JF Etter","year":"2008","unstructured":"Etter JF, Lukas RJ, Benowitz NL, West R, Dresler CM. Cytisine for smoking cessation: a research agenda. Drug Alcohol Depend. 2008;92(1\u20133):3\u20138.","journal-title":"Drug Alcohol Depend"},{"key":"4938_CR19","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1080\/13102818.2007.10817436","volume":"21","author":"V Tzankova","year":"2007","unstructured":"Tzankova V, Danchev N. Cytisine-from ethomedical use to the development as a natural alternative for smoking cessation. BiotechnolBiotechnol Eq. 2007;21:151\u201360.","journal-title":"BiotechnolBiotechnol Eq"},{"issue":"8125","key":"4938_CR20","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/S0140-6736(79)92963-5","volume":"1","author":"RM Forrester","year":"1979","unstructured":"Forrester RM. \"Have you eaten laburnum? Lancet. 1979;1(8125):1073.","journal-title":"Lancet"},{"issue":"25","key":"4938_CR21","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.1056\/NEJMoa1407764","volume":"371","author":"N Walker","year":"2014","unstructured":"Walker N, Howe C, Glover M, McRobbie H, Barnes J, Nosa V, Parag V, Bassett B, Bullen C. Cytisine versus nicotine for smoking cessation. N Engl J Med. 2014;371(25):2353\u201362.","journal-title":"N Engl J Med"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04938-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-024-04938-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-024-04938-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T07:06:33Z","timestamp":1732863993000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-024-04938-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,29]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["4938"],"URL":"https:\/\/doi.org\/10.1186\/s13256-024-04938-w","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,29]]},"assertion":[{"value":"11 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Ethical Review Board of the University Hospital (approval code 683CESC).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"None.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"578"}}