{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T04:10:06Z","timestamp":1746159006319,"version":"3.40.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82103356","82072614"],"award-info":[{"award-number":["82103356","82072614"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hubei Chen Xiaoping Science and Technology Development Foundation"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"DOI":"10.1186\/s13256-025-05211-4","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T14:21:25Z","timestamp":1746109285000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Malignant gastric glomus tumor with heterochronous liver metastases: a case report and review of the literature"],"prefix":"10.1186","volume":"19","author":[{"given":"Shining","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihao","family":"Zhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minhua","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,1]]},"reference":[{"issue":"8","key":"5211_CR1","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1097\/00000478-200008000-00008","volume":"24","author":"EM Gaertner","year":"2000","unstructured":"Gaertner EM, Steinberg DM, Huber M, et al. Pulmonary and mediastinal glomus tumors: report of five cases including a pulmonary glomangiosarcoma: a clinicopathologic study with literature review. Am J Surg Pathol. 2000;24(8):1105\u201314. https:\/\/doi.org\/10.1097\/00000478-200008000-00008.","journal-title":"Am J Surg Pathol"},{"key":"5211_CR2","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/j.ijscr.2020.04.067","volume":"70","author":"JG Aversa","year":"2020","unstructured":"Aversa JG, Monroe C, Levi A, Papanicolau-Sengos A, Kleiner DE, Hernandez JM. The first malignant primary hepatic glomus tumor: a case report. Int J Surg Case Rep. 2020;70:197\u2013200. https:\/\/doi.org\/10.1016\/j.ijscr.2020.04.067.","journal-title":"Int J Surg Case Rep"},{"issue":"3","key":"5211_CR3","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1097\/00000478-200203000-00003","volume":"26","author":"M Miettinen","year":"2002","unstructured":"Miettinen M, Paal E, Lasota J, Sobin LH. Gastrointestinal glomus tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 32 cases. Am J Surg Pathol. 2002;26(3):301\u201311. https:\/\/doi.org\/10.1097\/00000478-200203000-00003.","journal-title":"Am J Surg Pathol"},{"issue":"3","key":"5211_CR4","doi-asserted-by":"publisher","first-page":"E100","DOI":"10.1002\/dc.24914","volume":"50","author":"IA Pizzillo","year":"2022","unstructured":"Pizzillo IA, Fang C, Sun W, Brandler TC. Gastric glomus tumor diagnosed by fine needle aspiration of the stomach: A report of two cases and review of the literature. Diagn Cytopathol. 2022;50(3):E100\u20136. https:\/\/doi.org\/10.1002\/dc.24914.","journal-title":"Diagn Cytopathol"},{"issue":"1","key":"5211_CR5","doi-asserted-by":"publisher","first-page":"60","DOI":"10.5001\/omj.2016.11","volume":"31","author":"S Zaidi","year":"2016","unstructured":"Zaidi S, Arafah M. Malignant gastric glomus tumor: a case report and literature review of a rare entity. Oman Med J. 2016;31(1):60\u20134. https:\/\/doi.org\/10.5001\/omj.2016.11.","journal-title":"Oman Med J"},{"key":"5211_CR6","doi-asserted-by":"publisher","first-page":"339","DOI":"10.2147\/IMCRJ.S220455","volume":"12","author":"A Negahi","year":"2019","unstructured":"Negahi A, Jahanshahi F, Shahriari-Ahmadi A, Sadeghipour A. Lesser sac glomangiosarcoma with simultaneous liver and lymph nodes metastases mimicking small bowel gastrointestinal stromal tumor; immunohistochemistry and empirical chemotherapy. Int Med Case Rep J. 2019;12:339\u201344. https:\/\/doi.org\/10.2147\/IMCRJ.S220455.","journal-title":"Int Med Case Rep J"},{"issue":"36","key":"5211_CR7","doi-asserted-by":"publisher","first-page":"4616","DOI":"10.3748\/wjg.v16.i36.4616","volume":"16","author":"HQ Fang","year":"2010","unstructured":"Fang HQ. Clinicopathological features of gastric glomus tumor. WJG. 2010;16(36):4616. https:\/\/doi.org\/10.3748\/wjg.v16.i36.4616.","journal-title":"WJG"},{"issue":"3","key":"5211_CR8","doi-asserted-by":"publisher","first-page":"1634","DOI":"10.1007\/s00330-019-06534-9","volume":"30","author":"J Yoo","year":"2020","unstructured":"Yoo J, Kim SH, Han JK. Multiparametric MRI and (18)F-FDG PET features for differentiating gastrointestinal stromal tumors from benign gastric subepithelial lesions. Eur Radiol. 2020;30(3):1634\u201343. https:\/\/doi.org\/10.1007\/s00330-019-06534-9.","journal-title":"Eur Radiol"},{"issue":"22","key":"5211_CR9","doi-asserted-by":"publisher","first-page":"7052","DOI":"10.3748\/wjg.v21.i22.7052","volume":"21","author":"S Kato","year":"2015","unstructured":"Kato S, Kikuchi K, Chinen K, Murakami T, Kunishima F. Diagnostic utility of endoscopic ultrasound-guided fine-needle aspiration biopsy for glomus tumor of the stomach. World J Gastroenterol. 2015;21(22):7052\u20138. https:\/\/doi.org\/10.3748\/wjg.v21.i22.7052.","journal-title":"World J Gastroenterol"},{"issue":"3","key":"5211_CR10","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1159\/000326878","volume":"46","author":"M Gu","year":"2002","unstructured":"Gu M, Nguyen PT, Cao S, Lin F. Diagnosis of gastric glomus tumor by endoscopic ultrasound-guided fine needle aspiration biopsy. A case report with cytologic, histologic and immunohistochemical studies. Acta Cytol. 2002;46(3):560\u20136. https:\/\/doi.org\/10.1159\/000326878.","journal-title":"Acta Cytol"},{"issue":"1","key":"5211_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/00000478-200101000-00001","volume":"25","author":"AL Folpe","year":"2001","unstructured":"Folpe AL, Fanburg-Smith JC, Miettinen M, Weiss SW. Atypical and malignant glomus tumors: analysis of 52 cases, with a proposal for the reclassification of glomus tumors. Am J Surg Pathol. 2001;25(1):1\u201312. https:\/\/doi.org\/10.1097\/00000478-200101000-00001.","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"5211_CR12","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1097\/00000478-199602000-00012","volume":"20","author":"CD Brathwaite","year":"1996","unstructured":"Brathwaite CD, Poppiti RJ. Malignant glomus tumor: a case report of widespread metastases in a patient with multiple glomus body hamartomas. Am J Surg Pathol. 1996;20(2):233\u20138. https:\/\/doi.org\/10.1097\/00000478-199602000-00012.","journal-title":"Am J Surg Pathol"},{"issue":"2","key":"5211_CR13","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1111\/his.13303","volume":"72","author":"J Davis","year":"2018","unstructured":"Davis J, Petterson M, Newell J, Lauwers GY, Royce T, Demeure MJ. Micrometastatic gastric glomus tumour confirmed by next-generation sequencing. Histopathology. 2018;72(2):351\u20134. https:\/\/doi.org\/10.1111\/his.13303.","journal-title":"Histopathology"},{"issue":"4","key":"5211_CR14","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.clinre.2010.11.006","volume":"35","author":"M Xu","year":"2011","unstructured":"Xu M, Jiang XM, He YL, Zhang YL, Xu MD, Yao LQ. Glomus tumor of the stomach: a case treated by endoscopic submucosal dissection. Clin Res Hepatol Gastroenterol. 2011;35(4):325\u20138. https:\/\/doi.org\/10.1016\/j.clinre.2010.11.006.","journal-title":"Clin Res Hepatol Gastroenterol"},{"issue":"2","key":"5211_CR15","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.gie.2010.10.023","volume":"73","author":"Y Zhang","year":"2011","unstructured":"Zhang Y, Zhou P, Xu M, et al. Endoscopic diagnosis and treatment of gastric glomus tumors. Gastrointest Endosc. 2011;73(2):371\u20135. https:\/\/doi.org\/10.1016\/j.gie.2010.10.023.","journal-title":"Gastrointest Endosc"},{"issue":"8","key":"5211_CR16","doi-asserted-by":"publisher","first-page":"e719","DOI":"10.1111\/j.1365-2230.2009.03445.x","volume":"34","author":"APJJ Bray","year":"2009","unstructured":"Bray APJJ, Wong NACS, Narayan S. Cutaneous metastasis from gastric glomus tumour. Clin Exp Dermatol. 2009;34(8):e719\u201321. https:\/\/doi.org\/10.1111\/j.1365-2230.2009.03445.x.","journal-title":"Clin Exp Dermatol"},{"issue":"4","key":"5211_CR17","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1016\/j.athoracsur.2013.01.092","volume":"96","author":"Y Zhang","year":"2013","unstructured":"Zhang Y, Li H, Zhang W. Malignant glomus tumor of the esophagus with mediastinal lymph node metastases. Ann Thorac Surg. 2013;96(4):1464\u20136. https:\/\/doi.org\/10.1016\/j.athoracsur.2013.01.092.","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"5211_CR18","doi-asserted-by":"publisher","first-page":"358","DOI":"10.4132\/KoreanJPathol.2009.43.4.358","volume":"43","author":"H Lee","year":"2009","unstructured":"Lee H, Choi YS, Oh SC, et al. Malignant glomus tumors of the stomach\u2014a report of 2 cases with multiple metastases. Korean J Pathol. 2009;43(4):358. https:\/\/doi.org\/10.4132\/KoreanJPathol.2009.43.4.358.","journal-title":"Korean J Pathol"},{"issue":"4","key":"5211_CR19","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.radcr.2019.01.012","volume":"14","author":"L Toti","year":"2019","unstructured":"Toti L, Manzia TM, Roma S, et al. Rare malignant glomus tumor of the stomach with liver metastases. Radiol Case Rep. 2019;14(4):463\u20137. https:\/\/doi.org\/10.1016\/j.radcr.2019.01.012.","journal-title":"Radiol Case Rep"},{"issue":"11","key":"5211_CR20","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1002\/gcc.22102","volume":"52","author":"JM Mosquera","year":"2013","unstructured":"Mosquera JM, Sboner A, Zhang L, et al. Novel MIR143-NOTCH fusions in benign and malignant glomus tumors: novel MIR143-notch fusions in glomus tumors. Genes Chromosomes Cancer. 2013;52(11):1075\u201387. https:\/\/doi.org\/10.1002\/gcc.22102.","journal-title":"Genes Chromosomes Cancer"},{"issue":"11","key":"5211_CR21","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1097\/PAS.0000000000000913","volume":"41","author":"N Karamzadeh Dashti","year":"2017","unstructured":"Karamzadeh Dashti N, Bahrami A, Lee SJ, et al. BRAF V600E mutations occur in a subset of glomus tumors, and are associated with malignant histologic characteristics. Am J Surg Pathol. 2017;41(11):1532\u201341. https:\/\/doi.org\/10.1097\/PAS.0000000000000913.","journal-title":"Am J Surg Pathol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-025-05211-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-025-05211-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-025-05211-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T14:21:26Z","timestamp":1746109286000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-025-05211-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,1]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5211"],"URL":"https:\/\/doi.org\/10.1186\/s13256-025-05211-4","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,1]]},"assertion":[{"value":"9 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study does not need specialized ethic approval. All treatment of this case was followed routine clinical practice and multidisciplinary consultation advice. Written informed consent was obtained before treatment.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s legal guardian for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"199"}}