{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:12:50Z","timestamp":1790885570952,"version":"4.1.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"DOI":"10.1186\/s13256-025-05453-2","type":"journal-article","created":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T09:16:58Z","timestamp":1754385418000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy of hyperbaric oxygen therapy in treating fibromyalgia linked to childhood trauma after late-onset and over a decade of symptoms: a case report"],"prefix":"10.1186","volume":"19","author":[{"given":"Mouzayan","family":"Ginzarly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherif","family":"Khairy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zemer","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umair","family":"Qureshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghda","family":"Zaitoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shai","family":"Efrati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,5]]},"reference":[{"issue":"9","key":"5453_CR1","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1038\/nrrheum.2011.98","volume":"7","author":"T Schmidt-Wilcke","year":"2011","unstructured":"Schmidt-Wilcke T, Clauw DJ. Fibromyalgia: from pathophysiology to therapy. Nat Rev Rheumatol. 2011;7(9):518\u201327.","journal-title":"Nat Rev Rheumatol"},{"issue":"5","key":"5453_CR2","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1186\/ar2720","volume":"11","author":"D Buskila","year":"2009","unstructured":"Buskila D. Developments in the scientific and clinical understanding of fibromyalgia. Arthritis Res Ther. 2009;11(5):242.","journal-title":"Arthritis Res Ther"},{"issue":"3","key":"5453_CR3","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.berh.2007.03.006","volume":"21","author":"MB Yunus","year":"2007","unstructured":"Yunus MB. Role of central sensitization in symptoms beyond muscle pain, and the evaluation of a patient with widespread pain. Best Pract Res Clin Rheumatol. 2007;21(3):481\u201397.","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"2 Suppl 96","key":"5453_CR4","first-page":"S3","volume":"34","author":"JN Ablin","year":"2016","unstructured":"Ablin JN, Efrati S, Buskila D. Building up the pressure on chronic pain. Clin Exp Rheumatol. 2016;34(2 Suppl 96):S3-5.","journal-title":"Clin Exp Rheumatol"},{"issue":"1","key":"5453_CR5","doi-asserted-by":"publisher","first-page":"11599","DOI":"10.1038\/s41598-024-62161-5","volume":"14","author":"R Boussi-Gross","year":"2024","unstructured":"Boussi-Gross R, et al. Hyperbaric oxygen therapy vs. pharmacological intervention in adults with fibromyalgia related to childhood sexual abuse: prospective, randomized clinical trial. Sci Rep. 2024;14(1):11599.","journal-title":"Sci Rep"},{"key":"5453_CR6","doi-asserted-by":"publisher","first-page":"848","DOI":"10.3389\/fpsyg.2018.00848","volume":"9","author":"S Efrati","year":"2018","unstructured":"Efrati S, et al. Recovery of repressed memories in fibromyalgia patients treated with hyperbaric oxygen \u2013 Case series presentation and suggested bio-psycho-social mechanism. Front Psychol. 2018;9:848.","journal-title":"Front Psychol"},{"key":"5453_CR7","doi-asserted-by":"publisher","first-page":"2495","DOI":"10.3389\/fpsyg.2018.02495","volume":"9","author":"A Hadanny","year":"2018","unstructured":"Hadanny A, et al. Hyperbaric oxygen therapy can induce neuroplasticity and significant clinical improvement in patients suffering from fibromyalgia with a history of childhood sexual abuse-randomized controlled trial. Front Psychol. 2018;9:2495.","journal-title":"Front Psychol"},{"issue":"3","key":"5453_CR8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0282406","volume":"18","author":"JN Ablin","year":"2023","unstructured":"Ablin JN, et al. Hyperbaric oxygen therapy compared to pharmacological intervention in fibromyalgia patients following traumatic brain injury: a randomized, controlled trial. PLoS ONE. 2023;18(3): e0282406.","journal-title":"PLoS ONE"},{"issue":"4","key":"5453_CR9","first-page":"359","volume":"33","author":"CR Cramer","year":"1998","unstructured":"Cramer CR. Fibromyalgia and chronic fatigue syndrome: an update for athletic trainers. J Athl Train. 1998;33(4):359\u201361.","journal-title":"J Athl Train"},{"issue":"6","key":"5453_CR10","first-page":"337","volume":"7","author":"JC Branco","year":"1994","unstructured":"Branco JC, et al. Viral infection and fibromyalgia. Acta Med Port. 1994;7(6):337\u201341.","journal-title":"Acta Med Port"},{"issue":"8","key":"5453_CR11","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1097\/j.pain.0000000000002500","volume":"163","author":"B Kundakci","year":"2021","unstructured":"Kundakci B, Kaur J, Goh SL, Hall M, Doherty M, Zhang W, Abhishek A. Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomized controlled trials. Pain. 2021;163(8):1432\u201345. https:\/\/doi.org\/10.1097\/j.pain.0000000000002500.","journal-title":"Pain"},{"issue":"20","key":"5453_CR12","doi-asserted-by":"publisher","first-page":"5770","DOI":"10.1080\/09638288.2021.1954706","volume":"44","author":"C Climent-Sanz","year":"2021","unstructured":"Climent-Sanz C, Valenzuela-Pascual F, Mart\u00ednez-Navarro O, Blanco-Blanco J, Rub\u00ed-Carnacea F, Garc\u00eda-Mart\u00ednez E, Soler-Gonz\u00e1lez J, Barallat-Gimeno E, Gea-S\u00e1nchez M. Cognitive behavioral therapy for insomnia (CBT-i) in patients with fibromyalgia: a systematic review and meta-analysis. Disabil Rehabil. 2021;44(20):5770\u201383. https:\/\/doi.org\/10.1080\/09638288.2021.1954706.","journal-title":"Disabil Rehabil"},{"key":"5453_CR13","doi-asserted-by":"crossref","unstructured":"Skelly AC, Chou R, Dettori JR, Turner JA, Friedly JL, Rundell SD, Fu R, Brodt ED, Wasson N, Kantner S, Ferguson AJ. Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review update. NCBI Bookshelf. 2020. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK556229\/.","DOI":"10.23970\/AHRQEPCCER227"},{"issue":"1","key":"5453_CR14","first-page":"63","volume":"37 Suppl 116","author":"F Atzeni","year":"2019","unstructured":"Atzeni F, et al. Hyperbaric oxygen treatment of fibromyalgia: a prospective observational clinical study. Clin Exp Rheumatol. 2019;37 Suppl 116(1):63\u20139.","journal-title":"Clin Exp Rheumatol"},{"issue":"5","key":"5453_CR15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127012","volume":"10","author":"S Efrati","year":"2015","unstructured":"Efrati S, et al. Hyperbaric oxygen therapy can diminish fibromyalgia syndrome\u2014Prospective clinical trial. PLoS ONE. 2015;10(5): e0127012.","journal-title":"PLoS ONE"},{"key":"5453_CR16","doi-asserted-by":"publisher","first-page":"2114451","DOI":"10.1155\/2022\/2114451","volume":"2022","author":"I Gardoki-Souto","year":"2022","unstructured":"Gardoki-Souto I, et al. Prevalence and characterization of psychological trauma in patients with fibromyalgia: a cross-sectional study. Pain Res Manag. 2022;2022:2114451.","journal-title":"Pain Res Manag"},{"issue":"2","key":"5453_CR17","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1017\/S0033291720004547","volume":"51","author":"N Kaleycheva","year":"2021","unstructured":"Kaleycheva N, et al. The role of lifetime stressors in adult fibromyalgia: systematic review and meta-analysis of case-control studies. Psychol Med. 2021;51(2):177\u201393.","journal-title":"Psychol Med"},{"key":"5453_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/biom10060958","author":"A Hadanny","year":"2020","unstructured":"Hadanny A, Efrati S. The hyperoxic-hypoxic paradox. Biomolecules. 2020. https:\/\/doi.org\/10.3390\/biom10060958.","journal-title":"Biomolecules"},{"key":"5453_CR19","doi-asserted-by":"publisher","first-page":"1078544","DOI":"10.3389\/fneur.2022.1078544","volume":"13","author":"A Hadanny","year":"2022","unstructured":"Hadanny A, Efrati S. Editorial: hyperbaric oxygen and the brain. Front Neurol. 2022;13:1078544.","journal-title":"Front Neurol"},{"issue":"1","key":"5453_CR20","doi-asserted-by":"publisher","first-page":"132","DOI":"10.4103\/mgr.MEDGASRES-D-24-00029","volume":"15","author":"CV Borlongan","year":"2025","unstructured":"Borlongan CV, Hadanny A. Why provide 40 sessions of hyperbaric oxygen therapy to patients with traumatic brain injury? Med Gas Res. 2025;15(1):132\u20133.","journal-title":"Med Gas Res"},{"key":"5453_CR21","doi-asserted-by":"publisher","first-page":"1447742","DOI":"10.3389\/fneur.2024.1447742","volume":"15","author":"K Doenyas-Barak","year":"2024","unstructured":"Doenyas-Barak K, Efrati S. Optimizing hyperbaric oxygen therapy for PTSD\u2014The importance of dose and duration for sustained benefits. Front Neurol. 2024;15:1447742.","journal-title":"Front Neurol"},{"issue":"4","key":"5453_CR22","first-page":"395","volume":"50","author":"K Doenyas-Barak","year":"2023","unstructured":"Doenyas-Barak K, et al. Memory surfacing among veterans with PTSD receiving hyperbaric oxygen therapy. Undersea Hyperb Med. 2023;50(4):395\u2013401.","journal-title":"Undersea Hyperb Med"},{"key":"5453_CR23","doi-asserted-by":"publisher","first-page":"2535","DOI":"10.3389\/fpsyg.2018.02535","volume":"9","author":"R Lev-Wiesel","year":"2018","unstructured":"Lev-Wiesel R, et al. Brain and mind integration: childhood sexual abuse survivors experiencing hyperbaric oxygen treatment and psychotherapy concurrently. Front Psychol. 2018;9:2535.","journal-title":"Front Psychol"},{"issue":"3","key":"5453_CR24","first-page":"150","volume":"34","author":"J Freiberger","year":"2017","unstructured":"Freiberger J, Morgan L. Barotrauma in hyperbaric oxygen therapy: risk factors and management strategies. J Hyperbaric Med. 2017;34(3):150\u20138.","journal-title":"J Hyperbaric Med"},{"issue":"1","key":"5453_CR25","first-page":"45","volume":"61","author":"NB Hampson","year":"2018","unstructured":"Hampson NB, Pons S. Hyperbaric oxygen therapy in pregnancy: a critical review. J Obstetric Med. 2018;61(1):45\u201350.","journal-title":"J Obstetric Med"},{"issue":"2","key":"5453_CR26","first-page":"102","volume":"27","author":"RJ Goodman","year":"2019","unstructured":"Goodman RJ, Eelbeck LL. Seizure disorders and hyperbaric oxygen therapy: a systematic review. Neurol Res J. 2019;27(2):102\u20139.","journal-title":"Neurol Res J"},{"issue":"6","key":"5453_CR27","first-page":"320","volume":"39","author":"WR Thompson","year":"2021","unstructured":"Thompson WR, Saba A. Contraindications to hyperbaric oxygen therapy in pulmonary diseases. Pulmonary Med Rev. 2021;39(6):320\u20135.","journal-title":"Pulmonary Med Rev"},{"key":"5453_CR28","first-page":"34","volume":"55","author":"J Carr","year":"2018","unstructured":"Carr J, Hartsell T. Managing claustrophobia in hyperbaric oxygen therapy patients. J Anxiety Disord. 2018;55:34\u20138.","journal-title":"J Anxiety Disord"},{"issue":"3","key":"5453_CR29","first-page":"21","volume":"54","author":"L Poupon","year":"2021","unstructured":"Poupon L, Joliat R. Psychiatric conditions as contraindications to hyperbaric oxygen therapy. J Psychiatr Res. 2021;54(3):21\u201330.","journal-title":"J Psychiatr Res"},{"issue":"2","key":"5453_CR30","first-page":"86","volume":"12","author":"PG Harch","year":"2019","unstructured":"Harch PG, Boussi R. Oxygen toxicity and the high-pressure environment in hyperbaric oxygen therapy. J Clin Oxygen Med. 2019;12(2):86\u201392.","journal-title":"J Clin Oxygen Med"},{"issue":"2","key":"5453_CR31","first-page":"113","volume":"43","author":"A Hadanny","year":"2016","unstructured":"Hadanny A, Meir O, Bechor Y, Fishlev G, Bergan J, Efrati S. The safety of hyperbaric oxygen treatment\u2014Retrospective analysis in 2,334 patients. Undersea Hyperb Med. 2016;43(2):113\u201322.","journal-title":"Undersea Hyperb Med"},{"issue":"4","key":"5453_CR32","first-page":"395","volume":"50","author":"K Doenyas-Barak","year":"2023","unstructured":"Doenyas-Barak K, Kutz I, Lang E, Levi G, Efrati S. Memory surfacing among veterans with PTSD receiving hyperbaric oxygen therapy. PubMed. 2023;50(4):395\u2013401.","journal-title":"PubMed"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-025-05453-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-025-05453-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-025-05453-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T18:34:31Z","timestamp":1757356471000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-025-05453-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,5]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5453"],"URL":"https:\/\/doi.org\/10.1186\/s13256-025-05453-2","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,5]]},"assertion":[{"value":"6 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"MG, SK, ZW, UQ, and RZ work for the Brain and Performance Center. SE is a cofounder and shareholder at AVIV Scientific LTD.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"386"}}