{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T05:48:05Z","timestamp":1784180885652,"version":"3.55.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"DOI":"10.1186\/s13256-025-05532-4","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T11:03:19Z","timestamp":1759921399000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lupus pneumonitis in neonatal lupus: a case report"],"prefix":"10.1186","volume":"19","author":[{"given":"Naram","family":"Khalayli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lama","family":"Al-Darwish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4163-1111","authenticated-orcid":false,"given":"Maria","family":"Suleiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Alhaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maysoun","family":"Kudsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassel","family":"Salman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riham","family":"Suleiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,8]]},"reference":[{"issue":"4","key":"5532_CR1","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.pedhc.2013.07.015","volume":"28","author":"B Johnson","year":"2014","unstructured":"Johnson B. Overview of neonatal lupus. J Pediatr Health Care. 2014;28(4):331\u201341.","journal-title":"J Pediatr Health Care"},{"issue":"3","key":"5532_CR2","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1080\/15513815.2020.1836097","volume":"41","author":"X Yang","year":"2022","unstructured":"Yang X. Clinical features, autoantibodies, and outcome of neonatal lupus erythematosus. Fetal Pediatr Pathol. 2022;41(3):436\u201342.","journal-title":"Fetal Pediatr Pathol"},{"issue":"15","key":"5532_CR3","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.1080\/14767058.2017.1334048","volume":"31","author":"S Iijima","year":"2018","unstructured":"Iijima S. Fetal and neonatal involvement in maternal rheumatologic disease. J Matern Fetal Neonatal Med. 2018;31(15):2079\u201385.","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"2","key":"5532_CR4","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/j.rdc.2005.01.010","volume":"31","author":"JP Buyon","year":"2005","unstructured":"Buyon JP, Clancy RM. Neonatal lupus: basic research and clinical perspectives. Rheum Dis Clin North Am. 2005;31(2):299\u2013313.","journal-title":"Rheum Dis Clin North Am"},{"issue":"10","key":"5532_CR5","doi-asserted-by":"publisher","first-page":"3091","DOI":"10.1002\/art.24768","volume":"60","author":"C Llanos","year":"2009","unstructured":"Llanos C, Izmirly PM, Katholi M, Clancy RM, Friedman DM, Kim MY, et\u00a0al. Recurrence rates of cardiac manifestations associated with neonatal lupus and maternal\/fetal risk factors. Arthritis Rheum. 2009;60(10):3091\u20137.","journal-title":"Arthritis Rheum"},{"issue":"3","key":"5532_CR6","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1007\/s12016-017-8653-0","volume":"53","author":"F Vanoni","year":"2017","unstructured":"Vanoni F, Lava SAG, Fossali EF, Cavalli R, Simonetti GD, Bianchetti MG, et\u00a0al. Neonatal systemic lupus erythematosus syndrome: a comprehensive review. Clin Rev Allergy Immunol. 2017;53(3):469\u201376.","journal-title":"Clin Rev Allergy Immunol"},{"issue":"18","key":"5532_CR7","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.1161\/CIRCULATIONAHA.111.033894","volume":"124","author":"PM Izmirly","year":"2011","unstructured":"Izmirly PM, Saxena A, Kim MY, Wang D, Sahl SK, Llanos C, et\u00a0al. Maternal and fetal factors associated with mortality and morbidity in a multi-racial\/ethnic registry of anti-SSA\/Ro-associated cardiac neonatal lupus. Circ. 2011;124(18):1927\u201335.","journal-title":"Circ"},{"issue":"6\u20137","key":"5532_CR8","doi-asserted-by":"publisher","first-page":"A520","DOI":"10.1016\/j.autrev.2011.12.002","volume":"11","author":"G Carvalheiras","year":"2012","unstructured":"Carvalheiras G, Faria R, Braga J, Vasconcelos C. Fetal outcome in autoimmune diseases. Autoimmun Rev. 2012;11(6\u20137):A520\u201330.","journal-title":"Autoimmun Rev"},{"issue":"3","key":"5532_CR9","first-page":"230","volume":"43","author":"S Pereira","year":"2018","unstructured":"Pereira S, Flor-de-Lima F, Soares H, Vilan A, Ferraz C, Rodrigues M, et\u00a0al. Pulmonary involvement in neonatal lupus: a challenging diagnosis - Case report and literature review. Acta Reumatol Port. 2018;43(3):230\u20134.","journal-title":"Acta Reumatol Port"},{"issue":"3","key":"5532_CR10","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1097\/01.rhu.0000128871.51917.1d","volume":"10","author":"RL Morton","year":"2004","unstructured":"Morton RL, Moore C, Coventry S, Langston C, Schikler K, Eid NS. Pulmonary capillaritis and hemorrhage in neonatal lupus erythematosus (NLE). J Clin Rheumatol. 2004;10(3):130\u20133.","journal-title":"J Clin Rheumatol"},{"key":"5532_CR11","doi-asserted-by":"publisher","first-page":"232470962210778","DOI":"10.1177\/23247096221077815","volume":"10","author":"R Barreto Mota","year":"2022","unstructured":"Barreto Mota R, Santos NR, \u00c9den P, Rodrigues M, Brito I, Soares H. Lupus pneumonitis: case report of a rare manifestation of neonatal lupus. J Investig Med High Impact Case Rep. 2022;10:23247096221077816.","journal-title":"J Investig Med High Impact Case Rep"},{"issue":"1","key":"5532_CR12","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1177\/096120339100100109","volume":"1","author":"E Fonseca","year":"1991","unstructured":"Fonseca E, Contreras F, Garc\u00eda-Fr\u00edas E, Carrascosa MC. Neonatal lupus erythematosus with multisystem organ involvement preceding cutaneous lesions. Lupus. 1991;1(1):49\u201350.","journal-title":"Lupus"},{"issue":"3","key":"5532_CR13","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1111\/pde.12450","volume":"32","author":"L Padilla-Espa\u00f1a","year":"2015","unstructured":"Padilla-Espa\u00f1a L, D\u00edaz Cabrera R, Del Boz J, Lozano Calero C. Congenital lupus with multiorgan involvement: a case report and review of literature. Pediatr Dermatol. 2015;32(3):401\u20134.","journal-title":"Pediatr Dermatol"},{"issue":"2","key":"5532_CR14","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1055\/s-0039-1685537","volume":"40","author":"JR Hannah","year":"2019","unstructured":"Hannah JR, D\u2019Cruz DP. Pulmonary complications of systemic lupus erythematosus. Semin Respir Crit Care Med. 2019;40(2):227\u201334.","journal-title":"Semin Respir Crit Care Med"},{"issue":"6","key":"5532_CR15","first-page":"473","volume":"10","author":"R Gasparello-Almeida","year":"2008","unstructured":"Gasparello-Almeida R, Feitosa-Oliveira SK. Neonatal lupus erythematosus: an acquired autoimmune disorder and its cutaneous manifestations. Isr Med Assoc J. 2008;10(6):473\u20134.","journal-title":"Isr Med Assoc J"},{"issue":"13","key":"5532_CR16","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1177\/0961203316646461","volume":"25","author":"SA Wan","year":"2016","unstructured":"Wan SA, Teh CL, Jobli AT. Lupus pneumonitis as the initial presentation of systemic lupus erythematosus: case series from a single institution. Lupus. 2016;25(13):1485\u201390.","journal-title":"Lupus"},{"issue":"3","key":"5532_CR17","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.berh.2013.07.008","volume":"27","author":"LG Okon","year":"2013","unstructured":"Okon LG, Werth VP. Cutaneous lupus erythematosus: diagnosis and treatment. Best Pract Res Clin Rheumatol. 2013;27(3):391\u2013404.","journal-title":"Best Pract Res Clin Rheumatol"},{"issue":"1","key":"5532_CR18","doi-asserted-by":"publisher","first-page":"2476049","DOI":"10.1080\/07853890.2025.2476049","volume":"57","author":"W Sun","year":"2025","unstructured":"Sun W, Fu C, Jin X, Lei C, Zhu X. Neonatal lupus erythematosus: an acquired autoimmune disease to be taken seriously. Ann Med. 2025;57(1):2476049.","journal-title":"Ann Med"},{"issue":"9","key":"5532_CR19","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1093\/rheumatology\/kex191","volume":"56","author":"J Barsalou","year":"2017","unstructured":"Barsalou J, Jaeggi E, Laskin CA, Brown P, Tian SY, Hamilton RM, et\u00a0al. Prenatal exposure to antimalarials decreases the risk of cardiac but not non-cardiac neonatal lupus: a single-centre cohort study. Rheumatol. 2017;56(9):1552\u20139.","journal-title":"Rheumatol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-025-05532-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-025-05532-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-025-05532-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T11:03:20Z","timestamp":1759921400000},"score":1,"resource":{"primary":{"URL":"https:\/\/jmedicalcasereports.biomedcentral.com\/articles\/10.1186\/s13256-025-05532-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,8]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["5532"],"URL":"https:\/\/doi.org\/10.1186\/s13256-025-05532-4","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,8]]},"assertion":[{"value":"21 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors state that the procedures were followed according to the Declaration of Helsinki and the World Medical Association regarding human experimentation developed for the medical community.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s legal guardian for publication of this case report\u00a0and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"489"}}