{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:54:54Z","timestamp":1790790894185,"version":"4.1.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:00:00Z","timestamp":1774915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":42,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"DOI":"10.1186\/s13256-026-05922-2","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T19:26:01Z","timestamp":1774985161000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Severe respiratory complications in late-diagnosed Prader\u2013Willi syndrome: a case report"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4718-0398","authenticated-orcid":false,"given":"Surya Kant","family":"Tiwari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihar Ranjan","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rimjhim","family":"Sonowal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4126-3707","authenticated-orcid":false,"given":"Niladri Sekhar","family":"Bhunia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"key":"5922_CR1","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1136\/jmg.38.11.792","volume":"38","author":"JE Whittington","year":"2001","unstructured":"Whittington JE, Holland AJ, Webb T, Butler J, Clarke D, Boer H. Population prevalence and estimated birth incidence and mortality rate for people with Prader-Willi syndrome in one UK health region. J Med Genet. 2001;38:792\u20138.","journal-title":"J Med Genet"},{"key":"5922_CR2","unstructured":"Driscoll DJ, Miller JL, Cassidy SB. Prader\u2013Willi Syndrome. GeneReviews\u00ae. 1993."},{"key":"5922_CR3","doi-asserted-by":"publisher","DOI":"10.1210\/jcemcr\/luad146.045","volume":"2","author":"\u00d6 Ba\u015f Aksu","year":"2024","unstructured":"Ba\u015f Aksu \u00d6, Canpolat AG, Leblebici CB, Karabulut HG, \u00c7orap\u00e7\u0131o\u011flu D. O-16 never too late: delayed diagnosis of Prader-Willi syndrome. JCEM Case Rep. 2024;2: luad146.045.","journal-title":"JCEM Case Rep"},{"key":"5922_CR4","unstructured":"Daley SF, Fermin Gutierrez MA, Mendez MD. Prader\u2013Willi Syndrome. StatPearls. 2025."},{"key":"5922_CR5","doi-asserted-by":"publisher","first-page":"579","DOI":"10.2147\/DMSO.S141352","volume":"11","author":"A Crin\u00f2","year":"2018","unstructured":"Crin\u00f2 A, Fintini D, Bocchini S, Grugni G. Obesity management in Prader-Willi syndrome: current perspectives. Diabetes Metab Syndr Obes. 2018;11:579.","journal-title":"Diabetes Metab Syndr Obes"},{"key":"5922_CR6","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s11910-023-01254-6","volume":"23","author":"R Itani","year":"2023","unstructured":"Itani R, Gillett ES, Perez IA. Sleep consequences of Prader-Willi syndrome. Curr Neurol Neurosci Rep. 2023;23:25\u201332.","journal-title":"Curr Neurol Neurosci Rep"},{"key":"5922_CR7","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2020-000656","volume":"8","author":"ES Heilbrunn","year":"2021","unstructured":"Heilbrunn ES, Ssentongo P, Chinchilli VM, Oh J, Ssentongo AE. Sudden death in individuals with obstructive sleep apnoea: a systematic review and meta-analysis. BMJ Open Respir Res. 2021;8: e000656.","journal-title":"BMJ Open Respir Res"},{"key":"5922_CR8","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1007\/s40618-022-01831-5","volume":"45","author":"G Pugliese","year":"2022","unstructured":"Pugliese G, Barrea L, Sanduzzi Zamparelli A, de Alteriis G, Laudisio D, Muscogiuri G, Canora A, Bocchino M, Colao A, Savastano S. Body composition and obstructive sleep apnoea assessment in adult patients with Prader\u2013Willi syndrome: a case control study. J Endocrinol Invest. 2022;45:1967\u201375.","journal-title":"J Endocrinol Invest"},{"key":"5922_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.514","volume":"7","author":"J Duis","year":"2019","unstructured":"Duis J, van Wattum PJ, Scheimann A, et\u00a0al. A multidisciplinary approach to the clinical management of Prader\u2013Willi syndrome. Mol Genet Genomic Med. 2019;7: e514.","journal-title":"Mol Genet Genomic Med"},{"key":"5922_CR10","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1186\/s13256-023-04282-5","volume":"17","author":"KE Belay","year":"2023","unstructured":"Belay KE, Ayalew BL, Amogne MT, Alemneh TA, Geletew TK. A 14-year-old male patient with diagnosis of Prader-Willi syndrome in Ethiopia: a case report. J Med Case Rep. 2023;17:530.","journal-title":"J Med Case Rep"},{"key":"5922_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ppedcard.2025.101848","volume":"78","author":"N Yenduri","year":"2025","unstructured":"Yenduri N, Sasikumar N, Ahamed H, Yesodharan D, Kumar RK. A rare case report of an infant with Prader-Willi syndrome presenting with dilated cardiomyopathy and recurrent congestive heart failure. Prog Pediatr Cardiol. 2025;78: 101848.","journal-title":"Prog Pediatr Cardiol"},{"key":"5922_CR12","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12175504","volume":"12","author":"M Zaffanello","year":"2023","unstructured":"Zaffanello M, Pietrobelli A, Piacentini G, Guzzo A, Antoniazzi F. The impact of growth hormone therapy on sleep-related health outcomes in children with Prader\u2013 Willi syndrome: a review and clinical analysis. J Clin Med. 2023;12: 5504.","journal-title":"J Clin Med"},{"key":"5922_CR13","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s12887-023-04513-0","volume":"24","author":"H Guo","year":"2024","unstructured":"Guo H, Fu J, Zhou Y, Luo F, Cheng R. Evaluating the effect of recombinant human growth hormone treatment on sleep-related breathing disorders in toddlers with Prader\u2013 Willi syndrome: a one-year retrospective cohort study. BMC Pediatr. 2024;24:32.","journal-title":"BMC Pediatr"},{"key":"5922_CR14","unstructured":"Slowik JM, Sankari A, Collen JF. Obstructive sleep apnea. StatPearls. 2025."},{"key":"5922_CR15","doi-asserted-by":"publisher","first-page":"487","DOI":"10.21037\/tp-2024-537","volume":"14","author":"J Zhu","year":"2025","unstructured":"Zhu J, Jiao Q, Sun Y, et\u00a0al. A case report of Prader-Willi syndrome in a child with metabolic disorders and severe obstructive sleep apnea treated effectively with continuous positive airway pressure. Transl Pediatr. 2025;14:487\u201393.","journal-title":"Transl Pediatr"},{"key":"5922_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-019-1214-2","volume":"14","author":"DL Pacoricona Alfaro","year":"2019","unstructured":"Pacoricona Alfaro DL, Lemoine P, Ehlinger V, et\u00a0al. Causes of death in Prader-Willi syndrome: lessons from 11 years\u2019 experience of a national reference center. Orphanet J Rare Dis. 2019;14: 238.","journal-title":"Orphanet J Rare Dis"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-026-05922-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05922-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05922-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:47:02Z","timestamp":1778546822000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13256-026-05922-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,31]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5922"],"URL":"https:\/\/doi.org\/10.1186\/s13256-026-05922-2","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,31]]},"assertion":[{"value":"3 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Written informed consent was obtained from the patient's next-of-kin for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"261"}}