{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:16:13Z","timestamp":1777860973709,"version":"3.51.4"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":38,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Neurological complications in preeclampsia are uncommon and typically central in origin. Cranial mononeuropathies, especially involving the hypoglossal nerve, are exceedingly rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>We report a case of isolated hypoglossal nerve mononeuropathy in a 31-year-old, Indian, primigravida at 37\u00a0weeks of gestation with preeclampsia. The patient presented with mild dysphagia and dysarthria. Neurological examination revealed tongue deviation to the right, suggestive of left hypoglossal nerve mononeuropathy. Magnetic resonance imaging of the brain, including T1\/T2-weighted sequences, fluid-attenuated inversion recovery, and diffusion-weighted imaging with apparent diffusion coefficient sequences, and magnetic resonance angiography, followed by contrast-enhanced magnetic resonance imaging of the neck and oral cavity, showed\u00a0no infarct, hemorrhage, mass lesion, or compressive pathology. The patient was managed conservatively with blood pressure optimization, and symptoms resolved completely within 90\u00a0days postpartum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>At least four cases of hypoglossal nerve mononeuropathy associated with preeclampsia have been reported in literature. This case adds to the emerging evidence that cranial mononeuropathies may represent a rare but important neurological manifestation of preeclampsia and highlights the need for urgent neuroimaging and careful blood pressure control in pregnant and\/or postpartum patients presenting with bulbar symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13256-026-05935-x","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:05:17Z","timestamp":1774260317000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolated hypoglossal nerve mononeuropathy associated with preeclampsia in late pregnancy: a case report"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3170-6703","authenticated-orcid":false,"given":"Sandeep","family":"Kaur","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akashdeep Singh","family":"Chauhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"5935_CR1","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.ejogrb.2023.03.029","volume":"284","author":"B Kirubanandavari Sindhu","year":"2023","unstructured":"Kirubanandavari Sindhu B, Radhakrishnan S, Kumar Maurya D, Keepanasseril A. Isolated hypoglossal nerve palsy: a rare complication in preeclampsia. Eur J Obstet Gynecol Reprod Biol. 2023;284:206\u20137.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"1","key":"5935_CR2","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1097\/01.grf.0000153207.85996.4e","volume":"48","author":"WC Mabie","year":"2005","unstructured":"Mabie WC. Peripheral neuropathies during pregnancy. Clin Obstet Gynecol. 2005;48(1):57\u201366.","journal-title":"Clin Obstet Gynecol"},{"issue":"10022","key":"5935_CR3","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1016\/S0140-6736(15)00070-7","volume":"387","author":"BWJ Mol","year":"2016","unstructured":"Mol BWJ, Roberts CT, Thangaratinam S, Magee LA, de Groot CJM, Hofmeyr GJ. Pre-eclampsia. 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Neurol Clin Pract. 2021;11(5):e768\u20139.","journal-title":"Neurol Clin Pract"},{"issue":"4","key":"5935_CR6","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1016\/j.jocn.2011.06.028","volume":"19","author":"G Femia","year":"2012","unstructured":"Femia G, Parratt JD, Halmagyi GM. Isolated reversible hypoglossal nerve palsy as the initial manifestation of pre-eclampsia. J Clin Neurosci. 2012;19(4):602\u20133.","journal-title":"J Clin Neurosci"},{"issue":"2","key":"5935_CR7","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1159\/000524459","volume":"14","author":"P Zarifkar","year":"2022","unstructured":"Zarifkar P, Hansen K, Crone C, Svenstrup K, Larsen VA, Karlsson WK. A unique constellation of multiple cranial neuropathies in a patient with preeclampsia. Case Rep Neurol. 2022;14(2):256\u201360.","journal-title":"Case Rep Neurol"},{"key":"5935_CR8","doi-asserted-by":"crossref","unstructured":"Reich SG. Bell\u2019s palsy. CONTINUUM: lifelong learning in neurology. 2017;23(2):447\u201366.","DOI":"10.1212\/CON.0000000000000447"},{"issue":"10","key":"5935_CR9","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1016\/j.jogc.2017.04.031","volume":"39","author":"AJ Nieto-Calvache","year":"2017","unstructured":"Nieto-Calvache AJ, Loaiza-Osorio S, Casallas-Carrillo J, Escobar-Vidarte MF. Abducens nerve palsy in gestational hypertension: a case report and review of the literature. J Obstet Gynaecol Can. 2017;39(10):890\u20133.","journal-title":"J Obstet Gynaecol Can"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-026-05935-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05935-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05935-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T02:36:12Z","timestamp":1777516572000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13256-026-05935-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,23]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5935"],"URL":"https:\/\/doi.org\/10.1186\/s13256-026-05935-x","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,23]]},"assertion":[{"value":"18 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Full informed consent has been obtained from the individual to access her medical data and present it as a case for this publication.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"232"}}