{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T11:06:13Z","timestamp":1776251173000,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:00:00Z","timestamp":1772841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"vor","delay-in-days":39,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82460498"],"award-info":[{"award-number":["82460498"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"DOI":"10.1186\/s13256-026-05940-0","type":"journal-article","created":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T15:44:53Z","timestamp":1772898293000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multidisciplinary diagnosis and treatment of thyroid diffuse large B\u00a0cell lymphoma with tracheal invasion: a case report"],"prefix":"10.1186","volume":"20","author":[{"given":"Zhiqiang","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinjie","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingyang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Ying","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangtai","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9882-9477","authenticated-orcid":false,"given":"Yang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,7]]},"reference":[{"issue":"2","key":"5940_CR1","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1080\/08941939.2017.1383536","volume":"32","author":"ET Pavlidis","year":"2019","unstructured":"Pavlidis ET, Pavlidis TE. A review of primary thyroid lymphoma: molecular factors, diagnosis and management. J Invest Surg. 2019;32(2):137\u201342.","journal-title":"J Invest Surg"},{"key":"5940_CR2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina60030476","author":"O Vita","year":"2024","unstructured":"Vita O, Dema A, Barna R, et\u00a0al. Primary thyroid lymphoma: a retrospective-observational study in a single institutional center. Medicina (Kaunas). 2024. https:\/\/doi.org\/10.3390\/medicina60030476.","journal-title":"Medicina (Kaunas)"},{"key":"5940_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1064050","volume":"14","author":"JS Lee","year":"2023","unstructured":"Lee JS, Shin S, Yun HJ, et\u00a0al. Primary thyroid lymphoma: a single-center experience. Front Endocrinol (Lausanne). 2023;14: 1064050.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5","key":"5940_CR4","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1089\/thy.2021.0613","volume":"32","author":"N Suzuki","year":"2022","unstructured":"Suzuki N, Watanabe N, Noh JY, et\u00a0al. The relationship between primary thyroid lymphoma and various types of thyroid autoimmunity: a retrospective cohort study of 498 cases, including 9 cases with Graves\u2019 disease. Thyroid. 2022;32(5):552\u20139.","journal-title":"Thyroid"},{"issue":"4","key":"5940_CR5","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s40618-021-01712-3","volume":"45","author":"Y Zhu","year":"2022","unstructured":"Zhu Y, Yang S, He X. Prognostic evaluation models for primary thyroid lymphoma, based on the SEER database and an external validation cohort. J Endocrinol Invest. 2022;45(4):815\u201324.","journal-title":"J Endocrinol Invest"},{"issue":"4","key":"5940_CR6","doi-asserted-by":"publisher","DOI":"10.1097\/AS9.0000000000000226","volume":"3","author":"K Zhang","year":"2022","unstructured":"Zhang K, Peng X, Wei T, et\u00a0al. Prognostic nomogram and competing risk analysis of death for primary thyroid lymphoma: a long-term survival study of 1638 patients. Ann Surg Open. 2022;3(4): e226.","journal-title":"Ann Surg Open"},{"issue":"5","key":"5940_CR7","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/j.clon.2017.01.041","volume":"29","author":"DB Spielman","year":"2017","unstructured":"Spielman DB, Badhey A, Kadakia S, et\u00a0al. Rare thyroid malignancies: an overview for the oncologist. Clin Oncol (R Coll Radiol). 2017;29(5):298\u2013306.","journal-title":"Clin Oncol (R Coll Radiol)"},{"issue":"2","key":"5940_CR8","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1093\/ajcp\/aqz145","volume":"153","author":"A Travaglino","year":"2020","unstructured":"Travaglino A, Pace M, Varricchio S, et\u00a0al. Hashimoto thyroiditis in primary thyroid non-hodgkin lymphoma. Am J Clin Pathol. 2020;153(2):156\u201364.","journal-title":"Am J Clin Pathol"},{"key":"5940_CR9","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.ijscr.2020.09.069","volume":"75","author":"AR Perez","year":"2020","unstructured":"Perez AR, Perez MEC, Arcilla CEJ. Radical surgery for primary thyroid lymphoma in a Filipino female: report of a case and review of literature. Int J Surg Case Rep. 2020;75:302\u20136.","journal-title":"Int J Surg Case Rep"},{"issue":"9","key":"5940_CR10","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1634\/theoncologist.2013-0036","volume":"18","author":"S Walsh","year":"2013","unstructured":"Walsh S, Lowery AJ, Evoy D, et\u00a0al. Thyroid lymphoma: recent advances in diagnosis and optimal management strategies. Oncologist. 2013;18(9):994\u20131003.","journal-title":"Oncologist"},{"issue":"3","key":"5940_CR11","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1097\/RUQ.0000000000000414","volume":"35","author":"P Li","year":"2019","unstructured":"Li P, Zhang H. Ultrasonography in the diagnosis and monitoring of therapy for primary thyroid lymphoma. Ultrasound Q. 2019;35(3):246\u201352.","journal-title":"Ultrasound Q"},{"issue":"1","key":"5940_CR12","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1097\/CEJ.0000000000000599","volume":"30","author":"Y Wang","year":"2021","unstructured":"Wang Y, Wang S, Liu Z, et\u00a0al. Diagnosis methods and treatment strategy for primary thyroid lymphoma: a retrospective analysis of 41 cases in China. Eur J Cancer Prev. 2021;30(1):108\u201312.","journal-title":"Eur J Cancer Prev"},{"key":"5940_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.971249","volume":"13","author":"V Vander Poorten","year":"2022","unstructured":"Vander Poorten V, Goedseels N, Triantafyllou A, et\u00a0al. Effectiveness of core needle biopsy in the diagnosis of thyroid lymphoma and anaplastic thyroid carcinoma: a systematic review and meta-analysis. Front Endocrinol (Lausanne). 2022;13: 971249.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"5940_CR14","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1007\/s00330-015-3921-y","volume":"26","author":"EJ Ha","year":"2016","unstructured":"Ha EJ, Baek JH, Lee JH, et\u00a0al. Core needle biopsy could reduce diagnostic surgery in patients with anaplastic thyroid cancer or thyroid lymphoma. Eur Radiol. 2016;26(4):1031\u20136.","journal-title":"Eur Radiol"},{"issue":"1","key":"5940_CR15","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-023-02945-x","volume":"408","author":"C Gonz\u00e1lez-S\u00e1nchez","year":"2023","unstructured":"Gonz\u00e1lez-S\u00e1nchez C, Salvador-Egea MP, Gl\u00fcckmann-Maldonado E, et\u00a0al. Diagnosis and treatment of primary thyroid lymphoma from a surgical perspective: a multi-institutional study. Langenbecks Arch Surg. 2023;408(1): 206.","journal-title":"Langenbecks Arch Surg"},{"key":"5940_CR16","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00542","volume":"11","author":"J Yi","year":"2020","unstructured":"Yi J, Yi P, Wang W, et\u00a0al. A multicenter retrospective study of 58 patients with primary thyroid diffuse large B cell lymphoma. Front Endocrinol (Lausanne). 2020;11: 542.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"5940_CR17","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.radonc.2008.03.012","volume":"87","author":"H Yamashita","year":"2008","unstructured":"Yamashita H, Nakagawa K, Asari T, et\u00a0al. Radiotherapy for 41 patients with stages I and II MALT lymphoma: a retrospective study. Radiother Oncol. 2008;87(3):412\u20137.","journal-title":"Radiother Oncol"},{"issue":"2","key":"5940_CR18","doi-asserted-by":"publisher","first-page":"283","DOI":"10.3109\/10428194.2013.802317","volume":"55","author":"LJ Costa","year":"2014","unstructured":"Costa LJ, Xavier AC. Features and outcomes of diffuse large B-cell lymphoma of the thyroid in a large contemporary cohort. Leuk Lymphoma. 2014;55(2):283\u20137.","journal-title":"Leuk Lymphoma"},{"issue":"6","key":"5940_CR19","first-page":"2075","volume":"40","author":"M Alzouebi","year":"2012","unstructured":"Alzouebi M, Goepel JR, Horsman JM, et\u00a0al. Primary thyroid lymphoma: the 40 year experience of a UK lymphoma treatment centre. Int J Oncol. 2012;40(6):2075\u201380.","journal-title":"Int J Oncol"},{"key":"5940_CR20","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15051451","author":"Y Saito","year":"2023","unstructured":"Saito Y, Watanabe N, Suzuki N, et\u00a0al. Role of surgery in patients with stage IE primary thyroid MALT lymphoma staged by a modified classification system: the Tokyo classification. Cancers (Basel). 2023. https:\/\/doi.org\/10.3390\/cancers15051451.","journal-title":"Cancers (Basel)"},{"issue":"8","key":"5940_CR21","doi-asserted-by":"publisher","first-page":"3131","DOI":"10.1210\/jc.2013-1428","volume":"98","author":"SA Stein","year":"2013","unstructured":"Stein SA, Wartofsky L. Primary thyroid lymphoma: a clinical review. J Clin Endocrinol Metab. 2013;98(8):3131\u20138.","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-026-05940-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05940-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05940-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T10:22:01Z","timestamp":1776248521000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13256-026-05940-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,7]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5940"],"URL":"https:\/\/doi.org\/10.1186\/s13256-026-05940-0","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,7]]},"assertion":[{"value":"10 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Studies involving human participants were reviewed and approved by the First Affiliated Hospital of Gannan Medical University Ethics Committee.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"No competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"195"}}