{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:50:03Z","timestamp":1777949403280,"version":"3.51.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":41,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"National Key Research and Development Program of China","award":["Grant No. 2019YFC0840709"],"award-info":[{"award-number":["Grant No. 2019YFC0840709"]}]},{"name":"Open Project of the National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion","award":["Grant No. NCRCOP2023004"],"award-info":[{"award-number":["Grant No. NCRCOP2023004"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Lateral medullary syndrome, a common type of posterior circulation stroke, typically presents with classic symptoms including vertigo, gait ataxia, hoarseness, and dysphagia. In several cases, it may also lead to ipsilateral facial pain consistent with trigeminal neuralgia. Current management mainly involves pharmacological or surgical interventions, which are often associated with adverse effects and limited efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 52-year-old ethnic Han male patient with trigeminal neuralgia secondary to lateral medullary syndrome received structure-based medical acupuncture. After a 2-week intervention (six sessions per week), the patient\u2019s numerical rating scale score improved from 8 to 2, with a significant reduction in pain episode frequency. No adverse events were reported during treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Structure-based medical acupuncture, as an adjunct to conventional care, may alleviate facial pain symptoms in patients with trigeminal neuralgia secondary to lateral medullary syndrome. It may represent an effective complementary and alternative therapy option. Further rigorous, controlled clinical trials are warranted to validate its efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13256-026-05957-5","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T19:33:00Z","timestamp":1774380780000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Structure-based medical acupuncture for trigeminal neuralgia secondary to lateral medullary syndrome: a case report"],"prefix":"10.1186","volume":"20","author":[{"given":"Kaixuan","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiawei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linru","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zifeng","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzheng","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lili","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,24]]},"reference":[{"issue":"4","key":"5957_CR1","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1148\/rg.2019180126","volume":"39","author":"S Sciacca","year":"2019","unstructured":"Sciacca S, Lynch J, Davagnanam I, et al. Midbrain, pons, and medulla: anatomy and syndromes. Radiographics. 2019;39(4):1110\u201325. https:\/\/doi.org\/10.1148\/rg.2019180126.","journal-title":"Radiographics"},{"key":"5957_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2022.107329","volume":"219","author":"F Memmedova","year":"2022","unstructured":"Memmedova F, Ari Sevingil S, Jafarova U, et al. Progression rates of medulla oblongata infarcts in clinical follow-up: a retrospective study. Clin Neurol Neurosurg. 2022;219: 107329. https:\/\/doi.org\/10.1016\/j.clineuro.2022.107329. ([published Online First: 20220606]).","journal-title":"Clin Neurol Neurosurg"},{"issue":"3-4","key":"5957_CR3","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1159\/000455229","volume":"77","author":"LJ De Cocker","year":"2017","unstructured":"De Cocker LJ, Lovblad KO, Hendrikse J. MRI of cerebellar infarction. Eur Neurol. 2017;77(3\u20134):137\u201346. https:\/\/doi.org\/10.1159\/000455229. ([published Online First: 20170118]).","journal-title":"Eur Neurol"},{"key":"5957_CR4","unstructured":"Lui F, Tadi P, Anilkumar AC. Wallenberg Syndrome. StatPearls. Treasure Island (FL)2025."},{"issue":"5","key":"5957_CR5","first-page":"427","volume":"111","author":"O Amaechi","year":"2025","unstructured":"Amaechi O. Trigeminal neuralgia: rapid evidence review. Am Fam Physician. 2025;111(5):427\u201332.","journal-title":"Am Fam Physician"},{"issue":"6","key":"5957_CR6","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1001\/archneur.1993.00540060049016","volume":"50","author":"RL Sacco","year":"1993","unstructured":"Sacco RL, Freddo L, Bello JA. Wallenberg\u2019s lateral medullary syndrome. Clinical-magnetic resonance imaging correlations. Arch Neurol. 1993;50(6):609\u201314. https:\/\/doi.org\/10.1001\/archneur.1993.00540060049016.","journal-title":"Arch Neurol"},{"issue":"3","key":"5957_CR7","doi-asserted-by":"publisher","first-page":"376","DOI":"10.24875\/CIRU.19000801","volume":"88","author":"OO Gasca-Gonzalez","year":"2020","unstructured":"Gasca-Gonzalez OO, Perez-Cruz JC, Baldoncini M, et al. Neuroanatomical basis of Wallenberg syndrome. Cir Cir. 2020;88(3):376\u201382. https:\/\/doi.org\/10.24875\/CIRU.19000801.","journal-title":"Cir Cir"},{"key":"5957_CR8","unstructured":"Saleem F, Das JM. Lateral medullary syndrome. StatPearls. Treasure Island (FL)2025."},{"issue":"3","key":"5957_CR9","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1007\/s10194-011-0305-9","volume":"12","author":"CM Ordas","year":"2011","unstructured":"Ordas CM, Cuadrado ML, Simal P, et al. Wallenberg\u2019s syndrome and symptomatic trigeminal neuralgia. J Headache Pain. 2011;12(3):377\u201380. https:\/\/doi.org\/10.1007\/s10194-011-0305-9. ([published Online First: 20110210]).","journal-title":"J Headache Pain"},{"issue":"6","key":"5957_CR10","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1177\/0333102417726334","volume":"38","author":"A Jaimes","year":"2018","unstructured":"Jaimes A, Garcia-Saez R, Gutierrez-Viedma A, et al. Case report: Wallenberg\u2019s syndrome, a possible cause of symptomatic epicrania fugax. Cephalalgia. 2018;38(6):1203\u20136. https:\/\/doi.org\/10.1177\/0333102417726334. ([published Online First: 20170808]).","journal-title":"Cephalalgia"},{"issue":"5","key":"5957_CR11","doi-asserted-by":"publisher","DOI":"10.1111\/papr.70051","volume":"25","author":"BJ Snel","year":"2025","unstructured":"Snel BJ, Cohen SP, Erdine S, et al. 13. Trigeminal neuralgia. Pain Pract. 2025;25(5): e70051. https:\/\/doi.org\/10.1111\/papr.70051.","journal-title":"Pain Pract"},{"issue":"1","key":"5957_CR12","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1177\/09645284221118589","volume":"41","author":"CT Tang","year":"2023","unstructured":"Tang CT, Sookochoff M, Rhea L, et al. An audit of structure-based medical acupuncture by a single provider in patients with musculoskeletal pain using PROMIS scores as the outcome. Acupunct Med. 2023;41(1):48\u201354. https:\/\/doi.org\/10.1177\/09645284221118589. ([published Online First: 20220913]).","journal-title":"Acupunct Med"},{"issue":"3","key":"5957_CR13","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1136\/jnnp.62.3.297-a","volume":"62","author":"M Balestrino","year":"1997","unstructured":"Balestrino M, Leandri M. Trigeminal neuralgia in pontine ischaemia. J Neurol Neurosurg Psychiatry. 1997;62(3):297\u20138. https:\/\/doi.org\/10.1136\/jnnp.62.3.297-a.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3","key":"5957_CR14","doi-asserted-by":"publisher","first-page":"638","DOI":"10.4103\/neuroindia.NI_1323_15","volume":"65","author":"AA John","year":"2017","unstructured":"John AA, Abbas MM, Javali M, et al. A rare presentation of trigeminal neuralgia in lateral medullary syndrome. Neurol India. 2017;65(3):638\u201340. https:\/\/doi.org\/10.4103\/neuroindia.NI_1323_15.","journal-title":"Neurol India"},{"issue":"2","key":"5957_CR15","first-page":"63","volume":"24","author":"CT Huang","year":"2015","unstructured":"Huang CT, Lo CP, Chen YC, et al. A rare case of painful trigeminal neuropathy secondary to lateral medullary infarct: neuroimaging and electrophysiological studies. Acta Neurol Taiwan. 2015;24(2):63\u20138.","journal-title":"Acta Neurol Taiwan"},{"key":"5957_CR16","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1375587","volume":"15","author":"HX He","year":"2024","unstructured":"He HX, Li YX, Xiao YS, et al. The efficacy of acupuncture for trigeminal neuralgia: an overview of systematic reviews. Front Neurol. 2024;15: 1375587. https:\/\/doi.org\/10.3389\/fneur.2024.1375587. ([published Online First: 20240705]).","journal-title":"Front Neurol"},{"issue":"4","key":"5957_CR17","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1089\/acu.2020.1413","volume":"32","author":"L Meltz","year":"2020","unstructured":"Meltz L, Ortiz D, Chiang P. The anatomical relationship between acupoints of the face and the trigeminal nerve. Med Acupunct. 2020;32(4):181\u201393. https:\/\/doi.org\/10.1089\/acu.2020.1413. ([published Online First: 20200813]).","journal-title":"Med Acupunct"},{"key":"5957_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctcp.2023.101763","volume":"52","author":"L Ang","year":"2023","unstructured":"Ang L, Kim HJ, Heo JW, et al. Acupuncture for the treatment of trigeminal neuralgia: a systematic review and meta-analysis. Complement Ther Clin Pract. 2023;52: 101763. https:\/\/doi.org\/10.1016\/j.ctcp.2023.101763. ([published Online First: 20230502]).","journal-title":"Complement Ther Clin Pract"},{"issue":"4","key":"5957_CR19","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-016-0552-1","volume":"20","author":"S Patil","year":"2016","unstructured":"Patil S, Sen S, Bral M, et al. The role of acupuncture in pain management. Curr Pain Headache Rep. 2016;20(4): 22. https:\/\/doi.org\/10.1007\/s11916-016-0552-1.","journal-title":"Curr Pain Headache Rep"},{"issue":"27","key":"5957_CR20","first-page":"3042","volume":"26","author":"NZL Mao","year":"2017","unstructured":"Mao NZL, Wu K. Observation of the therapeutic effect of methylcobalamin combined with acupuncture on trigeminal neuralgia. Mod J Integr Tradit Chin West Med. 2017;26(27):3042\u20138.","journal-title":"Mod J Integr Tradit Chin West Med"},{"issue":"2","key":"5957_CR21","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1097\/j.pain.0000000000002031","volume":"162","author":"JH Jang","year":"2021","unstructured":"Jang JH, Song EM, Do YH, et al. Acupuncture alleviates chronic pain and comorbid conditions in a mouse model of neuropathic pain: the involvement of DNA methylation in the prefrontal cortex. Pain. 2021;162(2):514\u201330. https:\/\/doi.org\/10.1097\/j.pain.0000000000002031.","journal-title":"Pain"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-026-05957-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05957-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-05957-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:46:12Z","timestamp":1777851972000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13256-026-05957-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,24]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5957"],"URL":"https:\/\/doi.org\/10.1186\/s13256-026-05957-5","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,24]]},"assertion":[{"value":"10 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was not required for this single case report, in accordance with the institutional policy. Informed written consent to participate was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declared no potential conflicts of interest with respect to the research, authorship, and\/or publication of this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"236"}}