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This condition is associated with a high mortality rate, particularly in instances where timely surgical intervention is not conducted. Transesophageal echocardiography (TEE) is the preferred diagnostic modality, offering detailed visualization of the pathological communication between the pseudoaneurysm and the left ventricular outflow tract, along with its dynamic changes throughout the cardiac cycle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 28-year-old Han Chinese woman\u00a0with a congenital bicuspid aortic valve (BAV)\u00a0presented with recurrent fever\u00a0suggestive of infective endocarditis (IE). Cardiac ultrasound revealed\u00a0vegetations on the aortic valve\u00a0along with a mitral\u2013aortic intervalvular fibrosa pseudoaneurysm. Contrast-enhanced chest CT demonstrated a pseudoaneurysm communicating with the left ventricular outflow tract. The patient subsequently underwent aortic valve replacement and repair of the mitral\u2013aortic fibrous connection under extracorporeal circulation.\u00a0The patient recovered successfully with an uneventful postoperative course.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case underscores that congenital BAV is a significant predisposing factor for the rapid development of P-MAIVF in the setting of infective endocarditis. TEE is the diagnostic modality of choice for characterizing the lesion and its hemodynamic consequences. Early recognition and timely surgical intervention are crucial to prevent catastrophic rupture and ensure favorable outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13256-026-06047-2","type":"journal-article","created":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T12:55:05Z","timestamp":1776516905000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rapid formation of pseudoaneurysm of the mitral\u2013aortic intervalvular fibrosa in a patient with bicuspid aortic valve and infective endocarditis: a case report"],"prefix":"10.1186","volume":"20","author":[{"given":"Lanhua","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huizhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhai","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,18]]},"reference":[{"issue":"5","key":"6047_CR1","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1002\/uog.24762","volume":"59","author":"WJ Hogan","year":"2022","unstructured":"Hogan WJ, Punn R, Dean P, et al. Prenatally diagnosed pseudoaneurysm of mitral-aortic intervalvular fibrous area. Ultrasound Obstet Gynecol. 2022;59(5):682\u20136. https:\/\/doi.org\/10.1002\/uog.24762.","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"6047_CR2","doi-asserted-by":"publisher","first-page":"120","DOI":"10.4103\/aca.ACA_186_19","volume":"24","author":"A Hosseinsabet","year":"2021","unstructured":"Hosseinsabet A, Abbasi K. Pseudoaneurysm of the mitral-aortic intervalvular fibrosa in a patient with a history of Bentall operation. Ann Card Anaesth. 2021;24(1):120\u20131. https:\/\/doi.org\/10.4103\/aca.ACA_186_19.","journal-title":"Ann Card Anaesth"},{"issue":"8","key":"6047_CR3","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1016\/j.jaccas.2020.05.071","volume":"2","author":"M Kuroda","year":"2020","unstructured":"Kuroda M, Yamamoto H, Nakamura Y. Infective endocarditis complicated by pseudoaneurysm of the mitral-aortic intervalvular fibrosa without valvular involvement. 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A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"303"}}