{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T12:04:05Z","timestamp":1779969845063,"version":"3.53.1"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Med Case Reports"],"DOI":"10.1186\/s13256-026-06127-3","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T08:44:21Z","timestamp":1779957861000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pediatric mediastinal tumor unveiled as T-cell prolymphocytic leukemia: diagnostic pitfalls\u2014a case report"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0008-303X","authenticated-orcid":false,"given":"\u015eule","family":"\u00c7al\u0131\u015fkan Kam\u0131\u015f","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbaros \u015eahin","family":"Karag\u00fcn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulya","family":"Adamhasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Selcan","family":"Ko\u00e7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"issue":"6","key":"6127_CR1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.29042","volume":"68","author":"T Stachowicz-Stencel","year":"2021","unstructured":"Stachowicz-Stencel T, Synakiewicz A, Cornet M, Ferrari A, Garassino M, Masip JR, et al. Thymoma and thymic carcinoma in children and adolescents: the EXPeRT\/PARTNER diagnostic and therapeutic recommendations. Pediatr Blood Cancer. 2021;68(6): e29042. https:\/\/doi.org\/10.1002\/pbc.29042.","journal-title":"Pediatr Blood Cancer"},{"issue":"9","key":"6127_CR2","doi-asserted-by":"publisher","first-page":"2579","DOI":"10.1016\/j.radcr.2021.06.052","volume":"16","author":"C Brillantino","year":"2021","unstructured":"Brillantino C, Rossi E, Minelli R, Bifano D, Baldari D, Pizzicato P, et al. Mediastinal thymoma: a difficult diagnosis in the pediatric age. Radiol Case Rep. 2021;16(9):2579\u201385. https:\/\/doi.org\/10.1016\/j.radcr.2021.06.052.","journal-title":"Radiol Case Rep"},{"issue":"2","key":"6127_CR3","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1053\/j.semdp.2021.11.005","volume":"39","author":"DM Oramas","year":"2022","unstructured":"Oramas DM, Moran CA. Thymoma: histologically a heterogeneous group of tumors. Semin Diagn Pathol. 2022;39(2):99\u2013104. https:\/\/doi.org\/10.1053\/j.semdp.2021.11.005.","journal-title":"Semin Diagn Pathol"},{"issue":"9","key":"6127_CR4","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12092205","volume":"12","author":"C Rossi","year":"2022","unstructured":"Rossi C, Zanelli M, Sanguedolce F, Zizzo M, Palicelli A, Ricci L, et al. Pediatric thymoma: a review and update of the literature. Diagnostics Basel. 2022;12(9): 2205. https:\/\/doi.org\/10.3390\/diagnostics12092205.","journal-title":"Diagnostics Basel"},{"issue":"12","key":"6127_CR5","doi-asserted-by":"publisher","first-page":"2223","DOI":"10.1002\/pbc.25686","volume":"62","author":"B Mitton","year":"2015","unstructured":"Mitton B, Choi S, Koenigsmann M, Ranganathan S, Abromowitch M, Perkins SL. T-cell prolymphocytic leukemia in a 9-year-old girl. Pediatr Blood Cancer. 2015;62(12):2223\u20136. https:\/\/doi.org\/10.1002\/pbc.25686.","journal-title":"Pediatr Blood Cancer"},{"issue":"7","key":"6127_CR6","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1038\/s41375-022-01620-2","volume":"36","author":"R Alaggio","year":"2022","unstructured":"Alaggio R, Amador C, Anagnostopoulos I, Attygalle AD, Araujo IB, Berti E, Bhagat G, Borges AM, Boyer D, Calaminici M, Chadburn A. The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia. 2022;36(7):1720\u201348.","journal-title":"Leukemia"},{"issue":"14","key":"6127_CR7","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1182\/blood.2019001085","volume":"134","author":"PB Staber","year":"2019","unstructured":"Staber PB, Herling M, Bellido M, Jacobsen ED, Davids MS, Kadia TM, et al. Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia. Blood. 2019;134(14):1132\u201343. https:\/\/doi.org\/10.1182\/blood.2019001085.","journal-title":"Blood"},{"issue":"15","key":"6127_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241512106","volume":"24","author":"M Gutierrez","year":"2023","unstructured":"Gutierrez M, Bladek P, Goksu B, Murga-Zamalloa C, Bixby D, Wilcox R. T-cell prolymphocytic leukemia: diagnosis, pathogenesis, and treatment. Int J Mol Sci. 2023;24(15): 12106. https:\/\/doi.org\/10.3390\/ijms241512106.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"6127_CR9","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.13237","volume":"13","author":"A Colon Ramos","year":"2021","unstructured":"Colon Ramos A, Tarekegn K, Aujla A, Garcia de Jesus K, Gupta S. T-cell prolymphocytic leukemia: an overview of current and future approaches. Cureus. 2021;13(2): e13237. https:\/\/doi.org\/10.7759\/cureus.13237.","journal-title":"Cureus"},{"issue":"27","key":"6127_CR10","doi-asserted-by":"publisher","first-page":"2724","DOI":"10.1182\/bloodadvances.2017012515","volume":"1","author":"G Li","year":"2017","unstructured":"Li G, Sandlund JT, Luger SM, Bueso-Ramos C, Medeiros LJ, Tang G, et al. T-cell prolymphocytic leukemia in an adolescent with ataxia-telangiectasia harboring JAK3 mutations. Blood Adv. 2017;1(27):2724\u20138. https:\/\/doi.org\/10.1182\/bloodadvances.2017012515.","journal-title":"Blood Adv"},{"key":"6127_CR11","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/7310135","volume":"2024","author":"A Thammahong","year":"2024","unstructured":"Thammahong A, Chomchan P, Wattanawongdon W, Mutirangura A, Hongeng S, Pongrujikorn T. T-PLL presenting with an indolent course: alemtuzumab induction combined with allogeneic stem cell transplantation. Oxid Med Cell Longev. 2024;2024: 7310135. https:\/\/doi.org\/10.1155\/2024\/7310135.","journal-title":"Oxid Med Cell Longev"},{"issue":"14","key":"6127_CR12","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1042\/BCJ20240116","volume":"481","author":"J Von Jan","year":"2024","unstructured":"Von Jan J, Jentzsch L, Schmitt A, Herling M. Optimizing drug combinations for T-PLL: vulnerabilities to HDAC, BCL-2, CDK, and MDM2 inhibitors. Biochem J. 2024;481(14):1085\u2013100. https:\/\/doi.org\/10.1042\/BCJ20240116.","journal-title":"Biochem J"},{"issue":"11","key":"6127_CR13","doi-asserted-by":"publisher","first-page":"10007","DOI":"10.3390\/curroncol30110727","volume":"30","author":"HK Gjelberg","year":"2023","unstructured":"Gjelberg HK, Helgeland L, Liseth K, Micci F, Sandnes M, Russnes HG, Reikvam H. Long-smoldering T-prolymphocytic leukemia: A case report and a review of the literature. Curr Oncol. 2023;30(11):10007\u201318. https:\/\/doi.org\/10.3390\/curroncol30110727.","journal-title":"Curr Oncol"},{"issue":"3","key":"6127_CR14","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1053\/j.semdp.2021.06.010","volume":"41","author":"X Wang","year":"2024","unstructured":"Wang X, Wang W, Vega F, Quesada AE. Aggressive mediastinal lymphomas. Semin Diagn Pathol. 2024;41(3):125\u201339. https:\/\/doi.org\/10.1053\/j.semdp.2021.06.010.","journal-title":"Semin Diagn Pathol"}],"container-title":["Journal of Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13256-026-06127-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-06127-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13256-026-06127-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T11:23:38Z","timestamp":1779967418000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13256-026-06127-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,28]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["6127"],"URL":"https:\/\/doi.org\/10.1186\/s13256-026-06127-3","relation":{},"ISSN":["1752-1947"],"issn-type":[{"value":"1752-1947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,28]]},"assertion":[{"value":"31 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This case report was conducted in accordance with the ethical standards of the institutional and\/or national research committee and with the principles of the Declaration of Helsinki. As this study is a single case report, formal ethical committee approval was not required. Written informed consent for participation was obtained from the patient\u2019s legal guardian.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s legal guardian for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"293"}}