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This heterogeneity poses challenges for standardization of MSC characterization and potency assays as well as for MSC study comparability and manufacturing. This review discusses promising marker combinations for prospective MSC subpopulation enrichment and expansion, and reflects MSC phenotype changes due to environment and age. In order to address animal modelling in MSC biology, comparison of mouse and human MSC markers highlights current common ground of MSCs between species.<\/jats:p>","DOI":"10.1186\/s13287-015-0144-8","type":"journal-article","created":{"date-parts":[[2015,8,17]],"date-time":"2015-08-17T12:50:03Z","timestamp":1439815803000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Where is the common ground between bone marrow mesenchymal stem\/stromal cells from different donors and species?"],"prefix":"10.1186","volume":"6","author":[{"given":"Elena","family":"Jones","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,8,18]]},"reference":[{"key":"144_CR1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nm.3028","volume":"19","author":"P Bianco","year":"2013","unstructured":"Bianco P, Cao X, Frenette PS, Mao JJ, Robey PG, Simmons PJ, et al. 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