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All procedures were approved by the Ethics Committee of Xi\u2019an Central Hospital, Xi\u2019an Jiaotong University (Approved project: Extracellular Vesicle Biorepository, Approval No. LAS-L-2022-004-01, Date of approval: Mar 21, 2022), and complied with the standards of the National Health Research Institute. Umbilical cord guardians provided written informed consent for the use of samples. All animal procedures (Approved Project: Ethical Approval Document for Biological Research) were performed in accordance with the ARRIVE guidelines and approved by the Ethics Review Board of Xi\u2019an Central Hospital, Xi\u2019an Jiaotong University (Approval No.2021\u2009\u2212\u20091104, Date of approval, June 5, 2023).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing financial interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"255"}}