{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T17:23:46Z","timestamp":1740158626960,"version":"3.37.3"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62022056","81930001","62005160"],"award-info":[{"award-number":["62022056","81930001","62005160"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008750","name":"Shanghai Municipal Hospital Development Center","doi-asserted-by":"publisher","award":["SHDC2020CR3063B"],"award-info":[{"award-number":["SHDC2020CR3063B"]}],"id":[{"id":"10.13039\/501100008750","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Stem Cell Res Ther"],"DOI":"10.1186\/s13287-024-03908-9","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T03:31:03Z","timestamp":1726025463000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Connexin 25 maintains self-renewal and functions of airway basal cells for airway regeneration"],"prefix":"10.1186","volume":"15","author":[{"given":"Jingyuan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaoyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeyu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqiong","family":"Lei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongle","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Shan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"issue":"6","key":"3908_CR1","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/j.stemcr.2014.04.014","volume":"2","author":"SR Hough","year":"2014","unstructured":"Hough SR, Thornton M, Mason E, Mar JC, Wells CA, Pera MF. Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed states of human pluripotent stem cells. Stem Cell Rep. 2014;2(6):881\u201395. https:\/\/doi.org\/10.1016\/j.stemcr.2014.04.014.","journal-title":"Stem Cell Rep"},{"issue":"8","key":"3908_CR2","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1038\/nmeth.3016","volume":"11","author":"A Warmflash","year":"2014","unstructured":"Warmflash A, Sorre B, Etoc F, Siggia ED, Brivanlou AH. A method to recapitulate early embryonic spatial patterning in human embryonic stem cells. Nat Methods. 2014;11(8):847\u201354. https:\/\/doi.org\/10.1038\/nmeth.3016.","journal-title":"Nat Methods"},{"issue":"1","key":"3908_CR3","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.stemcr.2018.06.003","volume":"11","author":"L Yu","year":"2018","unstructured":"Yu L, Li J, Hong J, et al. Low cell-matrix adhesion reveals two subtypes of human pluripotent stem cells. Stem Cell Rep. 2018;11(1):142\u201356.","journal-title":"Stem Cell Rep"},{"issue":"10","key":"3908_CR4","doi-asserted-by":"publisher","first-page":"2041","DOI":"10.1002\/term.2739","volume":"12","author":"R Joshi","year":"2018","unstructured":"Joshi R, Fuller B, Mosadegh B, Tavana H. Stem cell colony interspacing effect on differentiation to neural cells. J Tissue Eng Regen Med. 2018;12(10):2041\u201354.","journal-title":"J Tissue Eng Regen Med"},{"issue":"5","key":"3908_CR5","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1016\/j.devcel.2015.01.011","volume":"32","author":"F Nallet-Staub","year":"2015","unstructured":"Nallet-Staub F, Yin X, Gilbert C, et al. Cell density sensing alters TGF-\u03b2 signaling in a cell-type-specific manner, independent from hippo pathway activation. Dev Cell. 2015;32(5):640\u201351. https:\/\/doi.org\/10.1016\/j.devcel.2015.01.011.","journal-title":"Dev Cell"},{"key":"3908_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121389","volume":"282","author":"MH Elsafi Mabrouk","year":"2022","unstructured":"Elsafi Mabrouk MH, Goetzke R, Abagnale G, et al. The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates. Biomaterials. 2022;282: 121389. https:\/\/doi.org\/10.1016\/j.biomaterials.2022.121389.","journal-title":"Biomaterials"},{"issue":"5","key":"3908_CR7","doi-asserted-by":"publisher","first-page":"1700832","DOI":"10.1002\/adhm.201700832","volume":"7","author":"R Joshi","year":"2018","unstructured":"Joshi R, Thakuri PS, Buchanan JC, Li J, Tavana H. Microprinted stem cell niches reveal compounding effect of colony size on stromal cells-mediated neural differentiation. Adv Healthc Mater. 2018;7(5):1700832.","journal-title":"Adv Healthc Mater"},{"issue":"5653","key":"3908_CR8","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1038\/272501a0","volume":"272","author":"TS Lawrence","year":"1978","unstructured":"Lawrence TS, Beers WH, Gilula NB. Transmission of hormonal stimulation by cell-to-cell communication. Nature. 1978;272(5653):501\u20136.","journal-title":"Nature"},{"key":"3908_CR9","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/BF02110109","volume":"28","author":"RD Veenstra","year":"1996","unstructured":"Veenstra RD. Size and selectivity of gap junction channels formed from different connexins. J Bioenerg Biomembr. 1996;28:327\u201337.","journal-title":"J Bioenerg Biomembr"},{"issue":"4","key":"3908_CR10","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1038\/nmeth1031","volume":"4","author":"VH Hernandez","year":"2007","unstructured":"Hernandez VH, Bortolozzi M, Pertegato V, et al. Unitary permeability of gap junction channels to second messengers measured by FRET microscopy. Nat Methods. 2007;4(4):353\u20138.","journal-title":"Nat Methods"},{"issue":"4","key":"3908_CR11","doi-asserted-by":"publisher","first-page":"3315","DOI":"10.1002\/jcp.26178","volume":"233","author":"M Wiesner","year":"2018","unstructured":"Wiesner M, Berberich O, Hoefner C, Blunk T, Bauer-Kreisel P. Gap junctional intercellular communication in adipose-derived stromal\/stem cells is cell density-dependent and positively impacts adipogenic differentiation. J Cell Physiol. 2018;233(4):3315\u201329.","journal-title":"J Cell Physiol"},{"issue":"11","key":"3908_CR12","doi-asserted-by":"publisher","first-page":"2221","DOI":"10.1093\/hmg\/ddt074","volume":"22","author":"Q Ke","year":"2013","unstructured":"Ke Q, Li L, Cai B, et al. Connexin 43 is involved in the generation of human-induced pluripotent stem cells. Hum Mol Genet. 2013;22(11):2221\u201333. https:\/\/doi.org\/10.1093\/hmg\/ddt074.","journal-title":"Hum Mol Genet"},{"issue":"2","key":"3908_CR13","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1002\/jcp.10365","volume":"197","author":"K Braet","year":"2003","unstructured":"Braet K, Aspeslagh S, Vandamme W, et al. Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1, 4, 5-trisphosphate and zero extracellular calcium in brain endothelial cells. J Cell Physiol. 2003;197(2):205\u201313.","journal-title":"J Cell Physiol"},{"issue":"4","key":"3908_CR14","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1083\/jcb.200604033","volume":"174","author":"G Reither","year":"2006","unstructured":"Reither G, Schaefer M, Lipp P. PKC\u03b1: a versatile key for decoding the cellular calcium toolkit. J Cell Biol. 2006;174(4):521\u201333.","journal-title":"J Cell Biol"},{"issue":"1","key":"3908_CR15","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/S0006-3495(99)76919-5","volume":"77","author":"AB Lansley","year":"1999","unstructured":"Lansley AB, Sanderson MJ. Regulation of airway ciliary activity by Ca2+: simultaneous measurement of beat frequency and intracellular Ca2+. Biophys J. 1999;77(1):629\u201338.","journal-title":"Biophys J"},{"issue":"5","key":"3908_CR16","doi-asserted-by":"publisher","first-page":"F939","DOI":"10.1152\/ajprenal.90612.2008","volume":"296","author":"J Yao","year":"2009","unstructured":"Yao J, Oite T, Kitamura M. Gap junctional intercellular communication in the juxtaglomerular apparatus. Am J Physiol Renal Physiol. 2009;296(5):F939\u201346.","journal-title":"Am J Physiol Renal Physiol"},{"issue":"2","key":"3908_CR17","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1161\/01.RES.0000257744.23795.93","volume":"100","author":"BE Isakson","year":"2007","unstructured":"Isakson BE, Ramos SI, Duling BR. Ca2+ and inositol 1, 4, 5-trisphosphate\u2013mediated signaling across the myoendothelial junction. Circ Res. 2007;100(2):246\u201354.","journal-title":"Circ Res"},{"issue":"5","key":"3908_CR18","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1101\/gad.1190504","volume":"18","author":"F McKeon","year":"2004","unstructured":"McKeon F. p63 and the epithelial stem cell: more than status quo? Genes Dev. 2004;18(5):465\u20139.","journal-title":"Genes Dev"},{"issue":"7718","key":"3908_CR19","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1038\/s41586-018-0393-7","volume":"560","author":"DT Montoro","year":"2018","unstructured":"Montoro DT, Haber AL, Biton M, et al. A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. Nature. 2018;560(7718):319\u201324.","journal-title":"Nature"},{"issue":"31","key":"3908_CR20","doi-asserted-by":"publisher","first-page":"12771","DOI":"10.1073\/pnas.0906850106","volume":"106","author":"JR Rock","year":"2009","unstructured":"Rock JR, Onaitis MW, Rawlins EL, et al. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci. 2009;106(31):12771\u20135.","journal-title":"Proc Natl Acad Sci"},{"key":"3908_CR21","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-020-00477-9","author":"RJ Hewitt","year":"2021","unstructured":"Hewitt RJ, Lloyd CM. Regulation of immune responses by the airway epithelial cell landscape. Nat Rev Immunol Published online. 2021. https:\/\/doi.org\/10.1038\/s41577-020-00477-9.","journal-title":"Nat Rev Immunol Published online"},{"issue":"6","key":"3908_CR22","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.devcel.2018.03.004","volume":"44","author":"EE Morrisey","year":"2018","unstructured":"Morrisey EE. Basal cells in lung development and repair. Dev Cell. 2018;44(6):653\u20134.","journal-title":"Dev Cell"},{"issue":"1","key":"3908_CR23","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.stem.2020.09.017","volume":"28","author":"FJ Hawkins","year":"2021","unstructured":"Hawkins FJ, et al. Derivation of airway basal stem cells from human pluripotent stem cells. Cell Stem Cell. 2021;28(1):79\u201395.","journal-title":"Cell Stem Cell"},{"issue":"3","key":"3908_CR24","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s13238-018-0506-y","volume":"9","author":"Q Ma","year":"2018","unstructured":"Ma Q, Ma Y, Dai X, et al. Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation. Protein Cell. 2018;9(3):267\u201382.","journal-title":"Protein Cell"},{"key":"3908_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2021.100182","volume":"13","author":"SL Chen","year":"2022","unstructured":"Chen SL, Chou HC, Lin KC, et al. Investigation of the role of the autophagic protein LC3B in the regulation of human airway epithelium cell differentiation in COPD using a biomimetic model. Mater Today Bio. 2022;13: 100182.","journal-title":"Mater Today Bio"},{"issue":"22","key":"3908_CR26","doi-asserted-by":"publisher","first-page":"4434","DOI":"10.1128\/MCB.00577-13","volume":"33","author":"T Yugawa","year":"2013","unstructured":"Yugawa T, et al. Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation. Mol Cell Biol. 2013;33(22):4434\u201347.","journal-title":"Mol Cell Biol"},{"issue":"6","key":"3908_CR27","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.stem.2011.04.003","volume":"8","author":"JR Rock","year":"2011","unstructured":"Rock JR, Gao X, Xue Y, Randell SH, Kong YY, Hogan BLM. Notch-dependent differentiation of adult airway basal stem cells. Cell Stem Cell. 2011;8(6):639\u201348.","journal-title":"Cell Stem Cell"},{"key":"3908_CR28","doi-asserted-by":"crossref","unstructured":"Heinzelmann K et al. Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis. Eur Respirat J. 2022;59(6).","DOI":"10.1183\/13993003.02373-2021"},{"key":"3908_CR29","doi-asserted-by":"crossref","unstructured":"Beyer EC, Berthoud VM. Gap junction gene and protein families: connexins, innexins, and pannexins. Biochimica et Biophysica Acta (BBA)-Biomembranes. 2018;1860(1):5\u20138.","DOI":"10.1016\/j.bbamem.2017.05.016"},{"issue":"3","key":"3908_CR30","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1007\/s00441-014-2078-3","volume":"360","author":"T Aasen","year":"2015","unstructured":"Aasen T. Connexins: junctional and non-junctional modulators of proliferation. Cell Tissue Res. 2015;360(3):685\u201399.","journal-title":"Cell Tissue Res"},{"key":"3908_CR31","doi-asserted-by":"publisher","first-page":"2775","DOI":"10.1007\/s00018-015-1958-3","volume":"72","author":"M Vinken","year":"2015","unstructured":"Vinken M. Introduction: connexins, pannexins and their channels as gatekeepers of organ physiology. Cell Mol Life Sci. 2015;72:2775\u20138.","journal-title":"Cell Mol Life Sci"},{"issue":"6","key":"3908_CR32","doi-asserted-by":"publisher","first-page":"L1085","DOI":"10.1152\/ajplung.2001.280.6.L1085","volume":"280","author":"V Abraham","year":"2001","unstructured":"Abraham V, Chou ML, George P, et al. Heterocellular gap junctional communication between alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2001;280(6):L1085\u201393.","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"5","key":"3908_CR33","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1165\/rcmb.2002-0281OC","volume":"29","author":"BE Isakson","year":"2003","unstructured":"Isakson BE, Seedorf GJ, Lubman RL, Evans WH, Boitano S. Cell\u2013cell communication in heterocellular cultures of alveolar epithelial cells. Am J Respir Cell Mol Biol. 2003;29(5):552\u201361.","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"9","key":"3908_CR34","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a029348","volume":"10","author":"M Delmar","year":"2018","unstructured":"Delmar M, Laird DW, Naus CC, Nielsen MS, Verselis VK, White TW. Connexins and disease. Cold Spring Harb Perspect Biol. 2018;10(9): a029348.","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"12","key":"3908_CR35","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1038\/nrc.2016.105","volume":"16","author":"T Aasen","year":"2016","unstructured":"Aasen T, Mesnil M, Naus CC, Lampe PD, Laird DW. Gap junctions and cancer: communicating for 50 years. Nat Rev Cancer. 2016;16(12):775\u201388.","journal-title":"Nat Rev Cancer"},{"key":"3908_CR36","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.biocel.2014.02.010","volume":"52","author":"S Crespin","year":"2014","unstructured":"Crespin S, Bacchetta M, Saab JB, et al. Cx26 regulates proliferation of repairing basal airway epithelial cells. Int J Biochem Cell Biol. 2014;52:152\u201360.","journal-title":"Int J Biochem Cell Biol"},{"issue":"5","key":"3908_CR37","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/j.femsre.2005.03.001","volume":"29","author":"EK Shiner","year":"2005","unstructured":"Shiner EK, Rumbaugh KP, Williams SC. Interkingdom signaling: deciphering the language of acyl homoserine lactones. FEMS Microbiol Rev. 2005;29(5):935\u201347.","journal-title":"FEMS Microbiol Rev"},{"key":"3908_CR38","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00372","author":"Y He","year":"2020","unstructured":"He Y, Ji P, Li Y, Wang R, Ma H, Yuan H. Genetic variants were associated with the prognosis of head and neck squamous carcinoma. Front Oncol. 2020. https:\/\/doi.org\/10.3389\/fonc.2020.00372.","journal-title":"Front Oncol"},{"issue":"3","key":"3908_CR39","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1007\/s12253-020-00806-2","volume":"26","author":"HJ Son","year":"2020","unstructured":"Son HJ, An CH, Yoo NJ, Lee SH. Tight junction-related CLDN5 and CLDN6 genes, and gap junction-related GJB6 and GJB7 genes are somatically mutated in gastric and colorectal cancers. Pathol Oncol Res. 2020;26(3):1983\u20137. https:\/\/doi.org\/10.1007\/s12253-020-00806-2.","journal-title":"Pathol Oncol Res"},{"issue":"1","key":"3908_CR40","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1038\/s41467-022-28903-7","volume":"13","author":"Y Hong","year":"2022","unstructured":"Hong Y, Shan S, Gu Y, et al. Malfunction of airway basal stem cells plays a crucial role in pathophysiology of tracheobronchopathia osteoplastica. Nat Commun. 2022;13(1):1309.","journal-title":"Nat Commun"},{"key":"3908_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2023.112732","volume":"245","author":"S Wang","year":"2023","unstructured":"Wang S, Shan S, Zhang J, et al. Airway epithelium regeneration by photoactivated basal cells. J Photochem Photobiol B. 2023;245: 112732.","journal-title":"J Photochem Photobiol B"},{"key":"3908_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2022.102637","volume":"106","author":"F Sultan","year":"2022","unstructured":"Sultan F, Ahuja K, Motiani RK. Potential of targeting host cell calcium dynamics to curtail SARS-CoV-2 infection and COVID-19 pathogenesis. Cell Calcium. 2022;106: 102637. https:\/\/doi.org\/10.1016\/j.ceca.2022.102637.","journal-title":"Cell Calcium"},{"issue":"8","key":"3908_CR43","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1172\/JCI26605","volume":"116","author":"K Parthasarathi","year":"2006","unstructured":"Parthasarathi K. Connexin 43 mediates spread of Ca2+ -dependent proinflammatory responses in lung capillaries. J Clin Investig. 2006;116(8):2193\u2013200. https:\/\/doi.org\/10.1172\/JCI26605.","journal-title":"J Clin Investig"},{"issue":"3","key":"3908_CR44","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.cell.2020.12.026","volume":"184","author":"A Gengatharan","year":"2021","unstructured":"Gengatharan A, Malvaut S, Marymonchyk A, et al. Adult neural stem cell activation in mice is regulated by the day\/night cycle and intracellular calcium dynamics. Cell. 2021;184(3):709\u201322.","journal-title":"Cell"},{"issue":"1","key":"3908_CR45","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.stem.2021.09.009","volume":"29","author":"Y Xie","year":"2022","unstructured":"Xie Y, Chen D, Jiang K, et al. Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-\u03b1 axis. Cell Stem Cell. 2022;29(1):70\u201385.","journal-title":"Cell Stem Cell"},{"issue":"3","key":"3908_CR46","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1158\/1078-0432.CCR-07-1184","volume":"14","author":"K Ezumi","year":"2008","unstructured":"Ezumi K, Yamamoto H, Murata K, et al. Aberrant expression of connexin 26 is associated with lung metastasis of colorectal cancer. Clin Cancer Res. 2008;14(3):677\u201384.","journal-title":"Clin Cancer Res"},{"key":"3908_CR47","doi-asserted-by":"crossref","unstructured":"Bouvard C et al. Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease. Eur Respirat J. 2020;55(3).","DOI":"10.1183\/13993003.00169-2019"}],"container-title":["Stem Cell Research &amp; Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-024-03908-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13287-024-03908-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-024-03908-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T03:44:52Z","timestamp":1726026292000},"score":1,"resource":{"primary":{"URL":"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-024-03908-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,11]]},"references-count":47,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3908"],"URL":"https:\/\/doi.org\/10.1186\/s13287-024-03908-9","relation":{},"ISSN":["1757-6512"],"issn-type":[{"type":"electronic","value":"1757-6512"}],"subject":[],"published":{"date-parts":[[2024,9,11]]},"assertion":[{"value":"1 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"<i>Title of the approved project<\/i>\u00a0Clinical exploration of bronchosopic infusion of autologus repairing airway epithelia cells for idiopathic pulmonary fibrosis.\u00a0<i>Name of the institutional approval committee or unit<\/i>\u00a0Ethics Committees of Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital.\u00a0<i>Approved number<\/i>\u00a02020\u2013152.\u00a0<i>Date of Approval<\/i>\u00a025th August 2020. <i>Title of the approved project<\/i>\u00a0Research on Femtosecond laser biophotonics.\u00a0<i>Name of the institutional approval committee or unit<\/i>\u00a0the Ethical Committee of Animal Experiments of School of Biomedical Engineering at Shanghai Jiao Tong University.\u00a0<i>Approved number<\/i>\u00a02019036.\u00a0<i>Date of Approval<\/i>\u00a09th March 2019. For the patients\u2019 samples, the patients or their guardians\/legally authorized representatives provided written informed consent for participation in the study and the use of samples.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"286"}}