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And the approval number is No: IACUC-D2202180, the date of approval was January 2023. The research protocols were conducted in accordance with the animal behavioral guidelines, using approved protocols from the institutional animal care committee. For umbilical cord mesenchymal stem cells (HucMSCs) collection, the study entitled \u201cStem cells are extracted from clinical patient samples (tissues, blood, body fluids) and aborted fetal tissues for basic regenerative medicine and clinical disease treatment research\u201d was approved by the Clinical Stem Cell Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School (Date: 11. 29. 2023, No.2017-161-08) and was conducted following approved institutional guidelines. Written informed consent was obtained from all donors prior to this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare that they have no competing interests. The authors declare that artificial intelligence is not used in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"435"}}