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All procedures involving animals were specifically reviewed and approved by the Institutional Animal Care and Use Committee (IACUC) at Tarbiat Modares University. Ethical approval for the study, encompassing both animal procedures and human blood donation, was granted by the Ethics Committee of the Faculty of Medical Sciences at Tarbiat Modares University under the permission number IR.MODARES.REC.1399.043, with the date of approval being June 22nd, 2020. 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