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PLoS ONE. 2019;14(2):e0211151. https:\/\/doi.org\/10.1371\/journal.pone.0211151.","journal-title":"PLoS ONE"}],"container-title":["Stem Cell Research & Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-025-04436-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13287-025-04436-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-025-04436-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T05:59:25Z","timestamp":1751349565000},"score":1,"resource":{"primary":{"URL":"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-025-04436-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":55,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4436"],"URL":"https:\/\/doi.org\/10.1186\/s13287-025-04436-w","relation":{},"ISSN":["1757-6512"],"issn-type":[{"value":"1757-6512","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,1]]},"assertion":[{"value":"19 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval for this study was obtained from the Ethics Committee of the Second Affiliated Hospital of Zhejiang University. For the animal experiments, approval was granted for the project titled \u201cMechanisms of Age-Related Cataracts and Drug Screening\u201d (Approval Number: 2024\u20130142; Date of approval: August 6, 2024). For the use of human-donated lenses, approval was obtained for the project titled \u201cStudy on Stemness Alterations and Differentiation Trajectories of Lens Epithelial Cells in Human-donated Lenses\u201d (Approval Number: 2023\u20130641; Date of approval: June 23, 2023). The organ donor(s) or their guardian(s)\/legally authorized representative(s) provided written informed consent for the use of samples. For ESCs, the original source (WiCell Research Institute, Inc.) has confirmed that there was initial ethical approval for collection of human cells, and that the donors had signed informed consent (\n                      \n                      ). The Material Transfer Agreement has been included in the Supplementary Material\n                      \n                      . All procedures involving animals and human tissues were conducted in strict compliance with the approved ethical guidelines and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"333"}}