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Med Res Arch. 2023;11(11).","DOI":"10.18103\/mra.v11i11.4784"}],"container-title":["Stem Cell Research & Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-025-04478-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13287-025-04478-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-025-04478-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T15:02:22Z","timestamp":1751814142000},"score":1,"resource":{"primary":{"URL":"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-025-04478-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,6]]},"references-count":116,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4478"],"URL":"https:\/\/doi.org\/10.1186\/s13287-025-04478-0","relation":{},"ISSN":["1757-6512"],"issn-type":[{"value":"1757-6512","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,6]]},"assertion":[{"value":"3 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All specimens were obtained in accordance with the tenets of the Declaration of Helsinki and anonymized. Human tracheal and bronchial samples were collected from n\u2009=\u20095 males and n\u2009=\u20094 female donors aged between 38 and 76 years. The donors provided informed consent for the use of their biological material for the present study, and ethical committee approval was obtained from all involved centres \u201cArcispedale S. Maria Nuova di Reggio Emilia\u201d, IRCCS, Reggio Emilia, Italy, (title \u201cPre-clinical study aimed at characterizing human respiratory epithelial stem cells, their differentiation pathways and potential use as an in vitro model for toxicity studies and tissue engineering\u201d; \u201cComitato Etico Area Vasta Emilia Nord\u201d, Protocol N. 2019\/0014725; date of approval 05\/02\/2019), and the \u201cFondazione Policlinico Universitario A. Gemelli\u201d, IRCCS, Rome, Italy (title \u201cPre-clinical study aimed at characterizing human respiratory epithelial stem cells, their differentiation pathways and potential use as an in vitro model for toxicity studies and tissue engineering\u201d; \u201cComitato Etico Territoriale Lazio Area 3\u201d N. 0008968\/21; date of approval 10\/03\/2021). Human skin samples were obtained from \u201cAzienda Ospedaliero-Universitaria di Modena\u201d, IRCSS, Modena, Italy\u201d from healthy living donors upon informed consent and compliance with Italian regulations (title \u201cHuman epithelial stem cells: characterization and development of clinical applications in Regenerative Medicine\u201d; Comitato Etico dell\u2019Area Vasta Emilia Nord, number 178\/09; date of approval 29\/09\/2009).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"All the authors provided consent for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"351"}}