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All procedures involving human tissues, peripheral blood samples, HaCaT cells, and animal experiments were performed in keeping with the guidelines of IEC for Clinical Research (Reference No.: [2020]292) and Animal Trials (Reference No.: [2023]038) of the First Affiliated Hospital of Sun Yat-sen University. We confirmed that the patient(s) or their guardian(s)\/legally authorized representative(s)\/next of kin provided written informed consent for participation in the study and\/or the use of samples.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"399"}}