{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:40:57Z","timestamp":1791492057792,"version":"4.3.4"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:00:00Z","timestamp":1768780800000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100005329","name":"Natural Science Foundation of Guizhou Province","doi-asserted-by":"publisher","award":["ZK [2025] 519"],"award-info":[{"award-number":["ZK [2025] 519"]}],"id":[{"id":"10.13039\/501100005329","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science-Technology Fund of Health Commission Guizhou Province","award":["gzwkj2024-195"],"award-info":[{"award-number":["gzwkj2024-195"]}]},{"name":"Transverse project fund of the affiliated stomatological hospital of Guizhou Medical University","award":["GYKQ2022HXZD05, GYKQKY202305"],"award-info":[{"award-number":["GYKQ2022HXZD05, GYKQKY202305"]}]},{"name":"Teaching Reform Program of Higher Education Institutions of Guizhou Provincial Department of Education","award":["2023143"],"award-info":[{"award-number":["2023143"]}]},{"name":"Key Project of Undergraduate Teaching Reform Research at Guizhou Medical University","award":["JG2023017"],"award-info":[{"award-number":["JG2023017"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Stem Cell Res Ther"],"DOI":"10.1186\/s13287-025-04824-2","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T09:36:15Z","timestamp":1765618575000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Mesenchymal stem cell therapy for radiation-induced xerostomia: a systematic review and network meta-analysis"],"prefix":"10.1186","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1305-7551","authenticated-orcid":false,"given":"Shen-sui","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-dong","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju-kun","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-dong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8642-3447","authenticated-orcid":false,"given":"Wei-li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6309-0486","authenticated-orcid":false,"given":"Zheng-long","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"issue":"3","key":"4824_CR1","first-page":"203","volume":"75","author":"LL Tang","year":"2025","unstructured":"Tang LL, Chen L, Xu GQ, Zhang N, Huang CL, Li WF, et al. Reduced-volume radiotherapy versus conventional-volume radiotherapy after induction chemotherapy in nasopharyngeal carcinoma: an open-label, noninferiority, multicenter, randomized phase 3 trial. CA Cancer J Clin. 2025;75(3):203\u201315.","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"4824_CR2","doi-asserted-by":"publisher","first-page":"e70038","DOI":"10.1002\/oto2.70038","volume":"9","author":"RJ Harley","year":"2025","unstructured":"Harley RJ, Bowers E, Li J, Bisignani M, Nilsen ML, Johnson JT. Biot\u00e8ne versus hydrasmile for Radiation-Induced xerostomia: randomized Double-Blind Cross-Over Study. OTO Open. 2025;9(1):e70038.","journal-title":"OTO Open"},{"issue":"1","key":"4824_CR3","first-page":"99","volume":"39","author":"SS Li","year":"2021","unstructured":"Li SS, et al. Advances on mechanism and treatment of salivary gland in radiation injury. West China J Stomatol. 2021;39(1):99\u2013104.","journal-title":"West China J Stomatol"},{"key":"4824_CR4","unstructured":"Katebi K, Hassanpour S, Eslami H, Salehnia F, Hosseinifard H. Effect of pilocarpine mouthwash on salivary flow rate in patients with xerostomia: a systematic review and meta-analysis. J Dent (Shiraz). 2023; 24(1 Suppl):76\u201383."},{"key":"4824_CR5","doi-asserted-by":"publisher","first-page":"109715","DOI":"10.1016\/j.radonc.2023.109715","volume":"186","author":"D Moral Nakamura","year":"2023","unstructured":"Moral Nakamura D, da Gra\u00e7a Pinto H, Baena Elchin C, Thomazotti Berard L, Abreu Alves F, Azeredo Alves Antunes L, et al. Efficacy of bethanechol chloride in the treatment of radiation-induced Xerostomia in patients with head and neck cancer: A systematic review and meta-analysis. Radiother Oncol. 2023;186:109715.","journal-title":"Radiother Oncol"},{"issue":"21","key":"4824_CR6","doi-asserted-by":"publisher","first-page":"11613","DOI":"10.3390\/ijms252111613","volume":"25","author":"JM Kim","year":"2024","unstructured":"Kim JM, Kim DH, Kim WT, Shin SC, Cheon YI, Park GC, et al. Amifostine and melatonin prevent acute salivary gland dysfunction 10 days after radiation through Anti-Ferroptosis and Anti-Ferritinophagy effects. Inter J Mol Sci. 2024;25(21):11613.","journal-title":"Inter J Mol Sci"},{"issue":"5","key":"4824_CR7","doi-asserted-by":"publisher","first-page":"e2410421","DOI":"10.1001\/jamanetworkopen.2024.10421","volume":"7","author":"R Crutcher","year":"2024","unstructured":"Crutcher R, Kim JK, Russin MP, Lukenbill J, Porosnicu M, Yost KJ, et al. Acupuncture for chronic Radiation-Induced Xerostomia in head and neck cancer: a multicenter randomized clinical trial. JAMA Netw Open. 2024;7(5):e2410421.","journal-title":"JAMA Netw Open"},{"issue":"3","key":"4824_CR8","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1016\/j.bulcan.2023.08.011","volume":"111","author":"K Lairedj","year":"2024","unstructured":"Lairedj K, Klausner G, Robijns J, Arany PR, Bensadoun RJ. Photobiomodulation Dans La pr\u00e9vention et La prise En charge des effets secondaires des traitements anticanc\u00e9reux: bases, Bilan et perspectives. Bull Cancer. 2024;111(3):314\u201326.","journal-title":"Bull Cancer"},{"key":"4824_CR9","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1007\/s12015-023-10641-y","volume":"20","author":"Y Cao","year":"2024","unstructured":"Cao Y, Yan J, Dong Z, Wang J, Jiang X, Cui T, et al. Adipose-derived mesenchymal stem cells are ideal for the cell-based treatment of refractory wounds: strong potential for angiogenesis. Stem Cell Rev Rep. 2024;20:313\u201328.","journal-title":"Stem Cell Rev Rep"},{"issue":"4","key":"4824_CR10","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1007\/s12015-024-10700-y","volume":"20","author":"AF Carlander","year":"2024","unstructured":"Carlander AF, Gundestrup AK, Jansson PM, Follin B, Hoeeg C, Kousholt BS, et al. Mesenchymal stromal\/stem cell therapy improves salivary flow rate in radiation-induced salivary gland hypofunction in preclinical in vivo models: a systematic review and meta-analysis. Stem Cell Rev Rep. 2024;20(4):1078\u201392.","journal-title":"Stem Cell Rev Rep"},{"key":"4824_CR11","doi-asserted-by":"publisher","first-page":"110093","DOI":"10.1016\/j.radonc.2024.110093","volume":"192","author":"GC Blitzer","year":"2024","unstructured":"Blitzer GC, Paz C, Glassey A, Ganz OR, Giri J, Pennati A, et al. Functionality of bone marrow mesenchymal stromal cells derived from head and neck cancer patients - A FDA-IND enabling study regarding MSC-based treatments for radiation-induced Xerostomia. Radiother Oncol. 2024;192:110093.","journal-title":"Radiother Oncol"},{"issue":"11","key":"4824_CR12","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1016\/j.jcyt.2023.07.009","volume":"25","author":"GC Blitzer","year":"2023","unstructured":"Blitzer GC, Glazer T, Burr A, Gustafson S, Ganz O, Meyers R, et al. Marrow-Derived autologous stromal cells for the restoration of salivary hypofunction (MARSH): a pilot, first-in-human study of interferon gamma-stimulated marrow mesenchymal stromal cells for treatment of radiation-induced Xerostomia. Cytotherapy. 2023;25(11):1139\u201344.","journal-title":"Cytotherapy"},{"issue":"10","key":"4824_CR13","doi-asserted-by":"publisher","first-page":"2078","DOI":"10.1158\/1078-0432.CCR-23-3675","volume":"30","author":"KK Jakobsen","year":"2024","unstructured":"Jakobsen KK, Carlander AF, Todsen T, Melchiors J, Paaske N, \u00d8stergaard Madsen AK, et al. Mesenchymal stem\/stromal cell therapy for radiation-induced xerostomia in previous head and neck cancer patients: a phase ii randomized, placebo-controlled trial. Clin Cancer Res. 2024;30(10):2078\u201384.","journal-title":"Clin Cancer Res"},{"issue":"1","key":"4824_CR14","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1186\/s13287-024-03833-x","volume":"15","author":"SG Jeon","year":"2024","unstructured":"Jeon SG, Lee J, Lee SJ, Seo J, Choi J, Bae DH, et al. Salivary gland organoid transplantation as a therapeutic option for radiation-induced Xerostomia. Stem Cell Res Ther. 2024;15(1):265.","journal-title":"Stem Cell Res Ther"},{"key":"4824_CR15","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1186\/s12903-025-06391-7","volume":"25","author":"A Abou-Bakr","year":"2025","unstructured":"Abou-Bakr A, Ahmed E, William H, Hassanein FEA. Frequency of periodontal disease in head and neck cancer patients after radiation therapy: a cross-sectional study. BMC Oral Health. 2025;25:1008.","journal-title":"BMC Oral Health"},{"issue":"7","key":"4824_CR16","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1007\/s00432-025-06213-x","volume":"151","author":"FEA Hassanein","year":"2025","unstructured":"Hassanein FEA, Mikhail C, Elkot S, Abou-Bakr A. L-arginine vs. L-glutamine oral suspensions for radiation-induced oral mucositis: a triple-blind randomized trial. J Cancer Res Clin Oncol. 2025;151(7):198.","journal-title":"J Cancer Res Clin Oncol"},{"issue":"11","key":"4824_CR17","doi-asserted-by":"publisher","first-page":"777","DOI":"10.7326\/M14-2385","volume":"162","author":"B Hutton","year":"2015","unstructured":"Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, et al. The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med. 2015;162(11):777\u201384.","journal-title":"Ann Intern Med"},{"key":"4824_CR18","first-page":"Ed000142","volume":"10","author":"M Cumpston","year":"2019","unstructured":"Cumpston M, Li T, Page MJ, Chandler J, Welch VA, Higgins JP, et al. Updated guidance for trusted systematic reviews: a new edition of the Cochrane handbook for systematic reviews of interventions. Cochrane Database Syst Rev. 2019;10:Ed000142.","journal-title":"Cochrane Database Syst Rev"},{"key":"4824_CR19","doi-asserted-by":"publisher","first-page":"l4898","DOI":"10.1136\/bmj.l4898","volume":"366","author":"JAC Sterne","year":"2019","unstructured":"Sterne JAC, Savovi\u0107 J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898.","journal-title":"BMJ"},{"key":"4824_CR20","unstructured":"Wells G, Shea B, O\u2019Connell D, Peterson J, Welch V, Losos M et al. The Newcastle\u2013Ottawa Scale for assessing the quality of nonrandomised studies in meta-analyses. https:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp"},{"key":"4824_CR21","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1002\/jrsm.41","volume":"2","author":"JM Hootman","year":"2011","unstructured":"Hootman JM, Driban JB, Sitler MR, Harris KP, Cattano NM. Reliability and validity of three quality rating instruments for systematic reviews of observational studies. Res Synth Methods. 2011;2:110\u20138.","journal-title":"Res Synth Methods"},{"key":"4824_CR22","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/jebm.12427","volume":"14","author":"Y Zhang","year":"2021","unstructured":"Zhang Y, Huang L, Wang D, Ren P, et al. The ROBINS-I and the NOS had similar reliability but differed in applicability: a random sampling observational studies of systematic reviews\/meta-analysis. J Evid-Based Med. 2021;14:112\u201322.","journal-title":"J Evid-Based Med"},{"issue":"2","key":"4824_CR23","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1002\/jrsm.1044","volume":"3","author":"JP Higgins","year":"2012","unstructured":"Higgins JP, Jackson D, Barrett JK, Lu G, Ades AE, White IR. Consistency and inconsistency in network meta-analysis: concepts and models for multi-arm studies. Res Synth Methods. 2012;3(2):98\u2013110.","journal-title":"Res Synth Methods"},{"issue":"7\u20138","key":"4824_CR24","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1002\/sim.3767","volume":"29","author":"S Dias","year":"2010","unstructured":"Dias S, Welton NJ, Caldwell DM, Ades AE. Checking consistency in mixed treatment comparison meta-analysis. Stat Med. 2010;29(7\u20138):932\u201344.","journal-title":"Stat Med"},{"issue":"13","key":"4824_CR25","doi-asserted-by":"publisher","first-page":"2890","DOI":"10.1158\/1078-0432.CCR-21-4520","volume":"28","author":"CD Lynggaard","year":"2022","unstructured":"Lynggaard CD, Gr\u00f8nh\u00f8j C, Jensen SB, Christensen R, Specht L, Andersen E, et al. Long-term safety of treatment with autologous mesenchymal stem cells in patients with Radiation-Induced xerostomia: primary results of the MESRIX phase I\/II randomized trial. Clin Cancer Res. 2022;28(13):2890\u20137.","journal-title":"Clin Cancer Res"},{"issue":"3","key":"4824_CR26","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1016\/j.ijrobp.2018.02.034","volume":"101","author":"C Gr\u00f8nh\u00f8j","year":"2018","unstructured":"Gr\u00f8nh\u00f8j C, Jensen DH, Vester-Glowinski P, Jensen SB, Bardow A, Oliveri RS, et al. Safety and efficacy of autologous Tissue-derived mesenchymal stem cells forRadiation-Induced xerostomia: a randomized, placebo-controlled phase I\/II trial (MESRIX). Int J Radiat Oncol Biol Phys. 2018;101(3):581\u201392.","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"5","key":"4824_CR27","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1158\/1078-0432.CCR-24-2663","volume":"31","author":"AL Fenger Carlander","year":"2025","unstructured":"Fenger Carlander AL, Jakobsen KK, Todsen T, Paaske N, \u00d8stergaard Madsen AK, Bendtsen SK, et al. Long-term effectiveness and safety of mesenchymal stromal cell therapy for Radiation-induced hyposalivation in head and neck cancer survivors: a randomized phase II trial. Clin Cancer Res. 2025;31(5):824\u201331.","journal-title":"Clin Cancer Res"},{"issue":"5","key":"4824_CR28","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1093\/stcltm\/szac011","volume":"11","author":"CD Lynggaard","year":"2022","unstructured":"Lynggaard CD, Gr\u00f8nh\u00f8j C, Christensen R, Fischer-Nielsen A, Melchiors J, Specht L, et al. Intraglandular Off-the-Shelf allogeneic mesenchymal stem cell treatment in patients with Radiation-Induced xerostomia: a safety study (MESRIX-II). Stem Cells Transl Med. 2022;11(5):478\u201389.","journal-title":"Stem Cells Transl Med"},{"issue":"6","key":"4824_CR29","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1093\/stcltm\/szae017","volume":"13","author":"KK Jakobsen","year":"2024","unstructured":"Jakobsen KK, Lynggaard CD, Paaske N, Carlander AF, Kastrup J, Hauge AW, et al. Long-Term outcome following treatment with allogeneic mesenchymal Stem\/Stromal cells for radiation- induced hyposalivation and Xerostomia. Stem Cells Transl Med. 2024;13(6):515\u201321.","journal-title":"Stem Cells Transl Med"},{"key":"4824_CR30","first-page":"e18015","volume":"43","author":"Mujtaba\u2002Rasool Arisha Akhtar, Rinad\u2002Akhtar","year":"2025","unstructured":"Arisha Akhtar, Rinad\u2002Akhtar Mujtaba\u2002Rasool, Muhammad Suhana\u2002FS, Asad Ali NS. Efficacy and safety of mesenchymal stem cell therapy in radiation induced Xerostomia in patients with head and neck carcinoma: a systematic review and meta analysis of randomized controlled trials. JCO. 2025;43:e18015\u201318015.","journal-title":"JCO"},{"key":"4824_CR31","doi-asserted-by":"publisher","first-page":"45","DOI":"10.2147\/TCRM.S76282","volume":"11","author":"A Villa","year":"2014","unstructured":"Villa A, Connell CL, Abati S. Diagnosis and management of Xerostomia and hyposalivation. Ther Clin Risk Manag. 2014;11:45\u201351.","journal-title":"Ther Clin Risk Manag"},{"issue":"4","key":"4824_CR32","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1007\/s12015-024-10700-y","volume":"20","author":"AF Carlander","year":"2024","unstructured":"Carlander AF, Gundestrup AK, Jansson PM, Follin B, Hoeeg C, Kousholt BS, et al. Mesenchymal stromal\/stem cell therapy improves salivary flow rate and restores salivary gland tissue architecture in preclinical models of radiation-induced xerostomia: a systematic review and meta-analysis. Stem Cell Rev Rep. 2024;20(4):1078\u201392.","journal-title":"Stem Cell Rev Rep"},{"issue":"1","key":"4824_CR33","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1186\/s13287-023-03301-y","volume":"14","author":"Z Guan","year":"2023","unstructured":"Guan Z, Zhang J, Jiang N, Tian M, Wang H, Liang B. Efficacy of mesenchymal stem cell therapy in rodent models of radiation-induced Xerostomia and oral mucositis: a systematic review. Stem Cell Res Ther. 2023;14(1):82.","journal-title":"Stem Cell Res Ther"},{"key":"4824_CR34","doi-asserted-by":"publisher","first-page":"e695","DOI":"10.1002\/term.2352","volume":"12","author":"JS Choi","year":"2018","unstructured":"Choi JS, An HY, Shin HS, Kim YM, Lim JY. Enhanced tissue remodelling efficacy of adipose-derived mesenchymal stem cells using injectable matrices in radiation-damaged salivary gland model. J Tissue Eng Regen Med. 2018;12:e695\u2013706.","journal-title":"J Tissue Eng Regen Med"},{"issue":"8","key":"4824_CR35","doi-asserted-by":"publisher","first-page":"904","DOI":"10.3390\/antiox13080904","volume":"13","author":"M Hu","year":"2024","unstructured":"Hu M, Hu L, Yang T, Zhou B, Feng X, Fan Z, et al. Intragland expression of the Shh gene alleviates Irradiation-Induced salivary gland injury through microvessel protection and the regulation of oxidative stress. Antioxid (Basel). 2024;13(8):904.","journal-title":"Antioxid (Basel)"},{"issue":"1","key":"4824_CR36","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1186\/s13046-022-02351-z","volume":"41","author":"Y Li","year":"2022","unstructured":"Li Y, Shen Z, Jiang X, Wang Y, Yang Z, Mao Y, et al. Mouse mesenchymal stem cell-derived Exosomal miR-466f-3p reverses EMT process through inhibiting AKT\/GSK3\u03b2 pathway via c-MET in radiation-induced lung injury. J Exp Clin Cancer Res. 2022;41(1):128.","journal-title":"J Exp Clin Cancer Res"},{"issue":"2","key":"4824_CR37","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1038\/s41401-022-00952-0","volume":"44","author":"L Qin","year":"2023","unstructured":"Qin L, Liu N, Bao CL, Yang DZ, Ma GX, Yi WH, et al. Mesenchymal stem cells in fibrotic diseases-the two sides of the same coin. Acta Pharmacol Sin. 2023;44(2):268\u201387.","journal-title":"Acta Pharmacol Sin"},{"key":"4824_CR38","doi-asserted-by":"publisher","first-page":"123518","DOI":"10.1016\/j.biomaterials.2025.123518","volume":"324","author":"Q Zhang","year":"2025","unstructured":"Zhang Q, Li J, Jia J, He S, Mei A, Zhang Z, et al. Topology scaffolds-enhanced paracrine of BMSCs through mechanotransduction-related metabolism reprogramming for burn wounds healing. Biomaterials. 2025;324:123518.","journal-title":"Biomaterials"},{"issue":"1","key":"4824_CR39","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1186\/s12951-025-03308-y","volume":"23","author":"Y Xie","year":"2025","unstructured":"Xie Y, Chai M, Xing Y, Zhou P, Wei P, Hua H. MiRNA let-7f-5p-encapsulated labial gland MSC-derived EVs ameliorate experimental Sj\u00f6gren\u2019s syndrome by suppressing Th17 cells via targeting RORC\/IL-17A signaling axis. J Nanobiotechnol. 2025;23(1):228.","journal-title":"J Nanobiotechnol"},{"issue":"1","key":"4824_CR40","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1186\/s13018-024-04846-1","volume":"19","author":"X Chen","year":"2024","unstructured":"Chen X, Zheng J, Yin L, Li Y, Liu H. Transplantation of three mesenchymal stem cells for knee osteoarthritis, which cell and type are more beneficial? A systematic review and network meta-analysis. J Ortho Surg Res. 2024;19(1):366.","journal-title":"J Ortho Surg Res"},{"key":"4824_CR41","doi-asserted-by":"crossref","unstructured":"Ding QX, Wang X, Li TS, Li YF, Li WY, Gao JH et al. Comparative Analysis of Short-Term and Long-Term Clinical Efficacy of Mesenchymal Stem Cells from Different Sources in Knee Osteoarthritis: A Network Meta-Analysis. Stem Cells Inter. 2024; 2024: 2741681.","DOI":"10.1155\/2024\/2741681"}],"container-title":["Stem Cell Research & Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-025-04824-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13287-025-04824-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13287-025-04824-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T19:36:43Z","timestamp":1768851403000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s13287-025-04824-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,13]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4824"],"URL":"https:\/\/doi.org\/10.1186\/s13287-025-04824-2","relation":{},"ISSN":["1757-6512"],"issn-type":[{"value":"1757-6512","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,13]]},"assertion":[{"value":"26 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"35"}}