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Animal protocols were approved by the Animal Ethics Committee (Project name: Study on the protective effect of rapamycin carbon dots on bone marrow Sca-1\n                      +\n                      stem cell dominance recovery in aged OPTN (E50K) mice against RGC injury; Approval committee: the Animal Ethics Committee of Second Affiliated Hospital of Harbin Medical University; Approval number: YJSDW2024-055; Approval date: May 29th 2024)( Project name: Nano carbon dots for the treatment of glaucoma; Approval committee: the Animal Ethics Committee of Second Affiliated Hospital of Harbin Medical University; Approval number: SYDW2023-101; Approval date: December 29th 2023), which is carried out according to\n                      ARRIVE\n                      guidelines 2.0. This study does not involve human participants, therefore, obtaining informed consent for participation and publication is not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"123"}}