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Regarding the ethics related to hucMSCs (Shandong Qilu Stem Cell Engineering Co., Ltd): after ethical review by the Medical Ethics Committee of Shandong Provincial Third Hospital (Ethical Approval No.: KYLL-2022015), the umbilical cord was voluntarily donated by the donor with a signed informed consent form, ensuring the source is compliant. The human lung microvascular endothelial cells were certified by ATCC and underwent ethical review before being applied in basic research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All figures in this article, including mechanism diagrams, were independently created by us using drawing software. They do not involve any third-party institutions and are free from copyright disputes.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Copyright Notice for Charts and Graphs"}},{"value":"The authors declare no competing interests. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors declare that they have not use AI-generated work in this manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"197"}}