{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T13:16:25Z","timestamp":1789650985304,"version":"4.0.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"National Research Foundation of Korea Grant funded by the Korean Government","award":["NRF-2020R1A2C1101082"],"award-info":[{"award-number":["NRF-2020R1A2C1101082"]}]},{"name":"National Research Foundation of Korea Grant funded by the Korean Government","award":["J. Kim"],"award-info":[{"award-number":["J. Kim"]}]},{"name":"Institute of Information & communications Technology Planning & Evaluation","award":["IITP-2023-RS-2023-00256629"],"award-info":[{"award-number":["IITP-2023-RS-2023-00256629"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["EJNMMI Res"],"DOI":"10.1186\/s13550-024-01181-8","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T07:03:18Z","timestamp":1732172598000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of shortening time on diagnosis of 18F-florbetaben PET"],"prefix":"10.1186","volume":"14","author":[{"given":"Phuong T. H.","family":"Trinh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doo-Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang-Ho","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4077-7722","authenticated-orcid":false,"given":"Jahae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"1181_CR1","unstructured":"Prince, M.J., et al., World Alzheimer Report 2015-The Global Impact of Dementia: An analysis of prevalence, incidence, cost and trends. 2015."},{"key":"1181_CR2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.clinbiochem.2019.04.015","volume":"72","author":"M Zverova","year":"2019","unstructured":"Zverova M. Clinical aspects of Alzheimer\u2019s disease. Clin Biochem. 2019;72:3\u20136.","journal-title":"Clin Biochem"},{"issue":"5","key":"1181_CR3","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006148","volume":"2","author":"R Tarawneh","year":"2012","unstructured":"Tarawneh R, Holtzman DM. The clinical problem of symptomatic Alzheimer disease and mild cognitive impairment. Cold Spring Harb Perspect Med. 2012;2(5): a006148.","journal-title":"Cold Spring Harb Perspect Med"},{"issue":"3","key":"1181_CR4","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1111\/j.1750-3639.1991.tb00661.x","volume":"1","author":"H Braak","year":"1991","unstructured":"Braak H, Braak E. Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections. Brain Pathol. 1991;1(3):213\u20136.","journal-title":"Brain Pathol"},{"issue":"9","key":"1181_CR5","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1038\/s41582-021-00520-w","volume":"17","author":"H Hampel","year":"2021","unstructured":"Hampel H, et al. Developing the ATX(N) classification for use across the Alzheimer disease continuum. Nat Rev Neurol. 2021;17(9):580\u20139.","journal-title":"Nat Rev Neurol"},{"issue":"4","key":"1181_CR6","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1212\/WNL.41.4.479","volume":"41","author":"SS Mirra","year":"1991","unstructured":"Mirra SS, et al. The consortium to establish a registry for alzheimer\u2019s disease (CERAD) Part II standardization of the neuropathologic assessment of alzheimer\u2019s disease. Neurology. 1991;41(4):479\u201386.","journal-title":"Neurology"},{"issue":"1","key":"1181_CR7","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/S0001-2998(81)80051-7","volume":"11","author":"ME Phelps","year":"1981","unstructured":"Phelps ME. Positron computed tomography studies of cerebral glucose metabolism in man: theory and application in nuclear medicine. Semin Nucl Med. 1981;11(1):32\u201349.","journal-title":"Semin Nucl Med"},{"issue":"1","key":"1181_CR8","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1053\/j.semnuclmed.2016.09.005","volume":"47","author":"A Mallik","year":"2017","unstructured":"Mallik A, Drzezga A, Minoshima S. Clinical amyloid imaging. Semin Nucl Med. 2017;47(1):31\u201343.","journal-title":"Semin Nucl Med"},{"issue":"7","key":"1181_CR9","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.3174\/ajnr.A4281","volume":"36","author":"AP Nayate","year":"2015","unstructured":"Nayate AP, et al. Use of standardized uptake value ratios decreases interreader variability of [18F] florbetapir PET Brain scan interpretation. AJNR Am J Neuroradiol. 2015;36(7):1237\u201344.","journal-title":"AJNR Am J Neuroradiol"},{"issue":"4","key":"1181_CR10","doi-asserted-by":"publisher","first-page":"e619","DOI":"10.1212\/WNL.0000000000011214","volume":"96","author":"ME Farrell","year":"2021","unstructured":"Farrell ME, et al. Defining the lowest threshold for amyloid-PET to predict future cognitive decline and amyloid accumulation. Neurology. 2021;96(4):e619\u201331.","journal-title":"Neurology"},{"issue":"1","key":"1181_CR11","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1007\/s00259-020-04942-4","volume":"48","author":"BJ Hanseeuw","year":"2021","unstructured":"Hanseeuw BJ, et al. Defining a centiloid scale threshold predicting long-term progression to dementia in patients attending the memory clinic: an [(18)F] flutemetamol amyloid PET study. Eur J Nucl Med Mol Imaging. 2021;48(1):302\u201310.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"1181_CR12","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s13195-020-00587-5","volume":"12","author":"S Amadoru","year":"2020","unstructured":"Amadoru S, et al. Comparison of amyloid PET measured in centiloid units with neuropathological findings in Alzheimer\u2019s disease. Alzheimers Res Ther. 2020;12(1):22.","journal-title":"Alzheimers Res Ther"},{"issue":"1","key":"1181_CR13","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s13195-019-0478-z","volume":"11","author":"G Salvado","year":"2019","unstructured":"Salvado G, et al. Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers. Alzheimers Res Ther. 2019;11(1):27.","journal-title":"Alzheimers Res Ther"},{"issue":"1","key":"1181_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jalz.2014.07.003","volume":"11","author":"WE Klunk","year":"2015","unstructured":"Klunk WE, et al. The centiloid project: standardizing quantitative amyloid plaque estimation by PET. Alzheimers Dement. 2015;11(1):1\u201315.","journal-title":"Alzheimers Dement"},{"key":"1181_CR15","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.nicl.2018.04.022","volume":"19","author":"Y Su","year":"2018","unstructured":"Su Y, et al. Utilizing the centiloid scale in cross-sectional and longitudinal PiB PET studies. Neuroimage Clin. 2018;19:406\u201316.","journal-title":"Neuroimage Clin"},{"issue":"5","key":"1181_CR16","doi-asserted-by":"crossref","first-page":"e662","DOI":"10.1212\/WNL.0000000000011222","volume":"96","author":"LM van der Kall","year":"2021","unstructured":"van der Kall LM, et al. Association of beta-amyloid level, clinical progression, and longitudinal cognitive change in normal older individuals. Neurology. 2021;96(5):e662\u201370.","journal-title":"Neurology"},{"issue":"8","key":"1181_CR17","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.2967\/jnumed.116.174615","volume":"57","author":"S Minoshima","year":"2016","unstructured":"Minoshima S, et al. SNMMI procedure standard\/EANM practice guideline for amyloid PET imaging of the brain 10. J Nucl Med. 2016;57(8):1316\u201322.","journal-title":"J Nucl Med"},{"issue":"1","key":"1181_CR18","doi-asserted-by":"publisher","first-page":"4825","DOI":"10.1038\/s41598-021-84358-8","volume":"11","author":"YJ Jeong","year":"2021","unstructured":"Jeong YJ, et al. Restoration of amyloid PET images obtained with short-time data using a generative adversarial networks framework. Sci Rep. 2021;11(1):4825.","journal-title":"Sci Rep"},{"issue":"2","key":"1181_CR19","doi-asserted-by":"publisher","first-page":"210","DOI":"10.2967\/jnumed.109.063701","volume":"51","author":"M Wardak","year":"2010","unstructured":"Wardak M, et al. Movement correction method for human brain PET images: application to quantitative analysis of dynamic 18F-FDDNP scans. J Nucl Med. 2010;51(2):210\u20138.","journal-title":"J Nucl Med"},{"issue":"3","key":"1181_CR20","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.jalz.2011.03.005","volume":"7","author":"GM McKhann","year":"2011","unstructured":"McKhann GM, et al. The diagnosis of dementia due to alzheimer\u2019s disease: recommendations from the National Institute on aging-Alzheimer\u2019s association workgroups on diagnostic guidelines for Alzheimer\u2019s disease. Alzheimers Dement. 2011;7(3):263\u20139.","journal-title":"Alzheimers Dement"},{"issue":"3","key":"1181_CR21","first-page":"CD010783","volume":"2015","author":"I Arevalo-Rodriguez","year":"2015","unstructured":"Arevalo-Rodriguez I, et al. Mini-mental state examination (MMSE) for the detection of Alzheimer\u2019s disease and other dementias in people with mild cognitive impairment (MCI). Cochrane Database Syst Rev. 2015;2015(3):CD010783.","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"1181_CR22","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1001\/archneur.65.8.1091","volume":"65","author":"SE O\u2019Bryant","year":"2008","unstructured":"O\u2019Bryant SE, et al. Staging dementia using clinical dementia rating scale sum of boxes scores: a texas alzheimer\u2019s research consortium study. Arch Neurol. 2008;65(8):1091\u20135.","journal-title":"Arch Neurol"},{"issue":"1","key":"1181_CR23","first-page":"S45","volume":"9","author":"JM Cedarbaum","year":"2013","unstructured":"Cedarbaum JM, et al. Rationale for use of the clinical dementia rating sum of boxes as a primary outcome measure for Alzheimer\u2019s disease clinical trials. Alzheimers Dement. 2013;9(1):S45-55.","journal-title":"Alzheimers Dement"},{"issue":"18","key":"1181_CR24","doi-asserted-by":"publisher","first-page":"2386","DOI":"10.1001\/jama.1993.03500180078038","volume":"269","author":"RM Crum","year":"1993","unstructured":"Crum RM, et al. Population-based norms for the mini-mental state examination by age and educational level. JAMA. 1993;269(18):2386\u201391.","journal-title":"JAMA"},{"issue":"2","key":"1181_CR25","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1007\/s00259-012-2268-8","volume":"40","author":"S Tiepolt","year":"2013","unstructured":"Tiepolt S, et al. Influence of scan duration on the accuracy of beta-amyloid PET with florbetaben in patients with Alzheimer\u2019s disease and healthy volunteers. Eur J Nucl Med Mol Imaging. 2013;40(2):238\u201344.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"1","key":"1181_CR26","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1159\/000089218","volume":"21","author":"CA Lynch","year":"2006","unstructured":"Lynch CA, et al. The clinical dementia rating sum of box score in mild dementia. Dement Geriatr Cogn Disord. 2006;21(1):40\u20133.","journal-title":"Dement Geriatr Cogn Disord"},{"issue":"1","key":"1181_CR27","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s41824-021-00123-0","volume":"6","author":"A Myoraku","year":"2022","unstructured":"Myoraku A, et al. Regional uptakes from early-frame amyloid PET and (18)F-FDG PET scans are comparable independent of disease state. Eur J Hybrid Imaging. 2022;6(1):2.","journal-title":"Eur J Hybrid Imaging"},{"key":"1181_CR28","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.neuroimage.2018.11.051","volume":"188","author":"AZ Kyme","year":"2019","unstructured":"Kyme AZ, et al. Open-field PET: simultaneous brain functional imaging and behavioural response measurements in freely moving small animals. Neuroimage. 2019;188:92\u2013101.","journal-title":"Neuroimage"},{"key":"1181_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2021.102773","volume":"31","author":"HJ Yoon","year":"2021","unstructured":"Yoon HJ, et al. Dual-phase (18)F-florbetaben PET provides cerebral perfusion proxy along with beta-amyloid burden in Alzheimer\u2019s disease. Neuroimage Clin. 2021;31: 102773.","journal-title":"Neuroimage Clin"},{"issue":"2","key":"1181_CR30","first-page":"2610","volume":"63","author":"D Kim","year":"2022","unstructured":"Kim D, et al. <strong>Internal and external validations of BTXBrain-Amyloid, AI-powered automated quantification software for amyloid PET<\/strong>. J Nucl Med. 2022;63(2):2610\u20132610.","journal-title":"J Nucl Med"},{"key":"1181_CR31","doi-asserted-by":"publisher","first-page":"3762651","DOI":"10.1155\/2017\/3762651","volume":"2017","author":"I Unal","year":"2017","unstructured":"Unal I. Defining an optimal cut-point value in ROC analysis: an alternative approach. Comput Math Methods Med. 2017;2017:3762651.","journal-title":"Comput Math Methods Med"},{"issue":"10","key":"1181_CR32","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1016\/S1474-4422(14)70194-2","volume":"13","author":"CR Jack Jr","year":"2014","unstructured":"Jack CR Jr, et al. Age-specific population frequencies of cerebral beta-amyloidosis and neurodegeneration among people with normal cognitive function aged 50\u201389 years: a cross-sectional study. Lancet Neurol. 2014;13(10):997\u20131005.","journal-title":"Lancet Neurol"},{"issue":"5","key":"1181_CR33","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/S1474-4422(11)70077-1","volume":"10","author":"H Barthel","year":"2011","unstructured":"Barthel H, et al. Cerebral amyloid-beta PET with florbetaben (18F) in patients with Alzheimer\u2019s disease and healthy controls: a multicentre phase 2 diagnostic study. Lancet Neurol. 2011;10(5):424\u201335.","journal-title":"Lancet Neurol"},{"issue":"5","key":"1181_CR34","doi-asserted-by":"publisher","first-page":"723","DOI":"10.2967\/jnumed.112.107185","volume":"54","author":"GA Becker","year":"2013","unstructured":"Becker GA, et al. PET quantification of 18F-florbetaben binding to beta-amyloid deposits in human brains. J Nucl Med. 2013;54(5):723\u201331.","journal-title":"J Nucl Med"},{"issue":"1","key":"1181_CR35","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s13550-021-00774-x","volume":"11","author":"J Li","year":"2021","unstructured":"Li J, et al. Correlation of [(18)F]florbetaben textural features and age of onset of Alzheimer\u2019s disease: a principal components analysis approach. EJNMMI Res. 2021;11(1):40.","journal-title":"EJNMMI Res"},{"key":"1181_CR36","doi-asserted-by":"publisher","DOI":"10.23736\/S1824-4785.19.03124-8","author":"B Paghera","year":"2019","unstructured":"Paghera B, et al. Comparison of visual criteria for amyloid-PET reading: could their merging reduce the inter-raters variability? Quart J Nucl Med Mol Imaging. 2019. https:\/\/doi.org\/10.23736\/S1824-4785.19.03124-8.","journal-title":"Quart J Nucl Med Mol Imaging"},{"issue":"4","key":"1181_CR37","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1007\/s00259-020-05044-x","volume":"48","author":"JY Kim","year":"2021","unstructured":"Kim JY, et al. Visual interpretation of [(18)F]Florbetaben PET supported by deep learning-based estimation of amyloid burden. Eur J Nucl Med Mol Imaging. 2021;48(4):1116\u201323.","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"4","key":"1181_CR38","doi-asserted-by":"publisher","first-page":"e228392","DOI":"10.1001\/jamanetworkopen.2022.8392","volume":"5","author":"Y Hu","year":"2022","unstructured":"Hu Y, et al. Assessment of a plasma amyloid probability score to estimate amyloid positron emission tomography findings among adults with cognitive impairment. JAMA Netw Open. 2022;5(4):e228392.","journal-title":"JAMA Netw Open"},{"issue":"7","key":"1181_CR39","doi-asserted-by":"publisher","first-page":"e688","DOI":"10.1212\/WNL.0000000000013211","volume":"98","author":"Y Li","year":"2022","unstructured":"Li Y, et al. Validation of plasma amyloid-beta 42\/40 for detecting alzheimer disease amyloid plaques. Neurology. 2022;98(7):e688\u201399.","journal-title":"Neurology"},{"issue":"5","key":"1181_CR40","doi-asserted-by":"publisher","first-page":"3179","DOI":"10.1002\/alz.13764","volume":"20","author":"MR Meyer","year":"2024","unstructured":"Meyer MR, et al. Clinical validation of the precivityAD2 blood test: a mass spectrometry-based test with algorithm combining %p-tau217 and Abeta42\/40 ratio to identify presence of brain amyloid. Alzheimers Dement. 2024;20(5):3179.","journal-title":"Alzheimers Dement"},{"issue":"5","key":"1181_CR41","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1002\/acn3.51763","volume":"10","author":"I Fogelman","year":"2023","unstructured":"Fogelman I, et al. Independent study demonstrates amyloid probability score accurately indicates amyloid pathology. Ann Clin Transl Neurol. 2023;10(5):765\u201378.","journal-title":"Ann Clin Transl Neurol"},{"issue":"1","key":"1181_CR42","doi-asserted-by":"publisher","first-page":"14950","DOI":"10.1038\/s41598-020-70978-z","volume":"10","author":"SH Cho","year":"2020","unstructured":"Cho SH, et al. Appropriate reference region selection of (18)F-florbetaben and (18)F-flutemetamol beta-amyloid PET expressed in Centiloid. Sci Rep. 2020;10(1):14950.","journal-title":"Sci Rep"},{"issue":"2","key":"1181_CR43","doi-asserted-by":"publisher","DOI":"10.1002\/dad2.12434","volume":"15","author":"W Coath","year":"2023","unstructured":"Coath W, et al. Operationalizing the centiloid scale for [(18)F]florbetapir PET studies on PET\/MRI. Alzheimers Dement (Amst). 2023;15(2): e12434.","journal-title":"Alzheimers Dement (Amst)"},{"key":"1181_CR44","first-page":"P14","volume":"15","author":"K Adamczuk","year":"2019","unstructured":"Adamczuk K, et al. Centiloid scale in practice: effect of different suvr reference regions and comparison of centiloid cut-OFFS. Alzheimers Dement. 2019;15:P14.","journal-title":"Alzheimers Dement"},{"key":"1181_CR45","doi-asserted-by":"publisher","first-page":"3843","DOI":"10.1118\/1.3613469","volume":"38","author":"A Ding","year":"2011","unstructured":"Ding A, et al. TH-A-214-04: impact of body size of obese patients on PET\/CT dose estimates: monte carlo calculations using a set of BMI-adjustable phantoms. Med Phys. 2011;38:3843.","journal-title":"Med Phys"},{"issue":"8926","key":"1181_CR46","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/S0140-6736(94)92871-1","volume":"344","author":"S Minoshima","year":"1994","unstructured":"Minoshima S, Foster N, Kuhl D. Posterior cingulate cortex in Alzheimer\u2019s disease. The Lancet. 1994;344(8926):895.","journal-title":"The Lancet"},{"issue":"3","key":"1181_CR47","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/S0306-4522(01)00108-7","volume":"104","author":"RJ Maddock","year":"2001","unstructured":"Maddock RJ, Garrett AS, Buonocore MH. Remembering familiar people: the posterior cingulate cortex and autobiographical memory retrieval. Neuroscience. 2001;104(3):667\u201376.","journal-title":"Neuroscience"},{"issue":"1","key":"1181_CR48","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1002\/ana.410420114","volume":"42","author":"S Minoshima","year":"1997","unstructured":"Minoshima S, et al. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer\u2019s disease. Ann Neurol. 1997;42(1):85\u201394.","journal-title":"Ann Neurol"},{"issue":"6","key":"1181_CR49","first-page":"670","volume":"24","author":"K Ishii","year":"1997","unstructured":"Ishii K, et al. Demonstration of decreased posterior cingulate perfusion in mild Alzheimer\u2019s disease by means of H215O positron emission tomography. Eur J Nucl Med. 1997;24(6):670\u20133.","journal-title":"Eur J Nucl Med"},{"issue":"8","key":"1181_CR50","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1136\/jnnp.54.8.672","volume":"54","author":"H Nyb\u00e4ck","year":"1991","unstructured":"Nyb\u00e4ck H, et al. Brain metabolism in Alzheimer\u2019s dementia: studies of 11C-deoxyglucose accumulation, CSF monoamine metabolites and neuropsychological test performance in patients and healthy subjects. J Neurol Neurosurg Psychiatry. 1991;54(8):672\u20138.","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"9","key":"1181_CR51","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1212\/01.wnl.0000240117.55680.0a","volume":"67","author":"NM Kemppainen","year":"2006","unstructured":"Kemppainen NM, et al. Voxel-based analysis of PET amyloid ligand [11C]PIB uptake in Alzheimer disease. Neurology. 2006;67(9):1575\u201380.","journal-title":"Neurology"},{"issue":"3","key":"1181_CR52","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1002\/ana.20009","volume":"55","author":"WE Klunk","year":"2004","unstructured":"Klunk WE, et al. Imaging brain amyloid in Alzheimer\u2019s disease with pittsburgh compound-B. Ann Neurol. 2004;55(3):306\u201319.","journal-title":"Ann Neurol"}],"container-title":["EJNMMI Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13550-024-01181-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13550-024-01181-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13550-024-01181-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T08:10:22Z","timestamp":1732176622000},"score":1,"resource":{"primary":{"URL":"https:\/\/ejnmmires.springeropen.com\/articles\/10.1186\/s13550-024-01181-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,21]]},"references-count":52,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["1181"],"URL":"https:\/\/doi.org\/10.1186\/s13550-024-01181-8","relation":{},"ISSN":["2191-219X"],"issn-type":[{"value":"2191-219X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,21]]},"assertion":[{"value":"20 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All patients were investigated within a retrospective study evaluating the diagnostic value <sup>18<\/sup>F-Florbetaben PET in Alzheimer\u2019s Disease which was approved by the Chonnam National University Hospital Ethics Committee (IRB no. CNUH 2022\/394). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The local institutional review board approved this retrospective study and waived the requirement for informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"114"}}