{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:08:32Z","timestamp":1789049312264,"version":"build-2803163510"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,8,29]],"date-time":"2017-08-29T00:00:00Z","timestamp":1503964800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"crossref"}]},{"name":"The Vitality Institute"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Health Econ Rev"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s13561-017-0166-2","type":"journal-article","created":{"date-parts":[[2017,8,29]],"date-time":"2017-08-29T11:17:18Z","timestamp":1504005438000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Adjusting health spending for the presence of comorbidities: an application to United States national inpatient data"],"prefix":"10.1186","volume":"7","author":[{"given":"Joseph L.","family":"Dieleman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranju","family":"Baral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Bulchis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxwell","family":"Birger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony L.","family":"Bui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeline","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"Chapin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Gabert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Hamavid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody","family":"Horst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liya","family":"Lomsadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Squires","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Tobias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,8,29]]},"reference":[{"issue":"7 Suppl 1","key":"166_CR1","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1097\/MLR.0b013e3181a23e12","volume":"47","author":"AB Rosen","year":"2009","unstructured":"Rosen AB, Cutler DM. Challenges in building disease-based National Health Accounts. Med Care. 2009;47(7 Suppl 1):S7\u201313.","journal-title":"Med Care"},{"issue":"4","key":"166_CR2","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1370\/afm.983","volume":"7","author":"JM Valderas","year":"2009","unstructured":"Valderas JM, Starfield B, Sibbald BSC, Roland M. Defining comorbidity: implications for understanding health and health services. Ann Fam Med. 2009;7(4):357\u201363.","journal-title":"Ann Fam Med"},{"issue":"9","key":"166_CR3","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1016\/j.jclinepi.2012.02.017","volume":"65","author":"D Sarfati","year":"2012","unstructured":"Sarfati D. Review of methods used to measure comorbidity in cancer populations: no gold standard exists. J Clin Epidemiol. 2012;65(9):924\u201333.","journal-title":"J Clin Epidemiol"},{"issue":"3","key":"166_CR4","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1006\/pmed.1999.0534","volume":"29","author":"TA Hodgson","year":"1999","unstructured":"Hodgson TA, Cohen AJ. Medical care expenditures for diabetes, its chronic complications, and its comorbidities. Prev Med. 1999;29(3):173\u201386.","journal-title":"Prev Med"},{"key":"166_CR5","doi-asserted-by":"crossref","unstructured":"JL Wolff, B. Starfield, G. Anderson. Prevalence, expenditures, and complications of multiple chronic conditions in the elderly. Arch Intern Med 2002;162(20):2269\u20132276.","DOI":"10.1001\/archinte.162.20.2269"},{"key":"166_CR6","doi-asserted-by":"crossref","unstructured":"Martin Fortin, Hassan Soubhi, Catherine Hudon, Elizabeth A Bayliss, Marjan van den Akker. Multimorbidity\u2019s many challenges. BMJ 2007;334(7602):1016\u20131017.","DOI":"10.1136\/bmj.39201.463819.2C"},{"issue":"4","key":"166_CR7","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1377\/hlthaff.23.4.176","volume":"23","author":"E Meara","year":"2004","unstructured":"Meara E, White C, Cutler DM. Trends in medical spending by age, 1963-2000. Health Aff (Millwood). 2004;23(4):176\u201383.","journal-title":"Health Aff (Millwood)"},{"key":"166_CR8","doi-asserted-by":"publisher","first-page":"920","DOI":"10.1056\/NEJMsa054744","volume":"355","author":"DM Cutler","year":"2006","unstructured":"Cutler DM, Rosen AB, Vijan S. The value of medical spending in the United States, 1960-2000. N Engl J Med. 2006;355:920\u20137.","journal-title":"N Engl J Med"},{"issue":"1","key":"166_CR9","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1071\/AH080148","volume":"32","author":"S Begg","year":"2008","unstructured":"Begg S, Vos T, Goss J, Mann N. An alternative approach to projecting health expenditure in Australia. Aust Health Rev. 2008;32(1):148\u201355.","journal-title":"Aust Health Rev"},{"issue":"19","key":"166_CR10","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1097\/BRS.0b013e3181b1fad1","volume":"34","author":"BI Martin","year":"2009","unstructured":"Martin BI, Turner JA, Mirza SK, Lee MJ, Comstock BA, Deyo RA. Trends in health care expenditures, utilization, and health status among US adults with spine problems, 1997-2006. Spine. 2009;34(19):2077\u201384.","journal-title":"Spine"},{"key":"166_CR11","unstructured":"Dementia in Australia: National data analysis and development. Canberra: Australian Institute of Health and Welfare; 2006. Report No.: AIHW cat. no. AGE 53."},{"issue":"1","key":"166_CR12","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3111\/13696998.2014.969434","volume":"18","author":"J Rizzo","year":"2015","unstructured":"Rizzo J, Chen J, Gunnarsson C, Naim A, Lofland J. Adjusting for comorbidities in cost of illness studies. J Med Econ. 2015;18(1):12\u201328.","journal-title":"J Med Econ"},{"issue":"2","key":"166_CR13","doi-asserted-by":"publisher","first-page":"207","DOI":"10.2165\/00019053-200119020-00007","volume":"19","author":"B Bloom","year":"2001","unstructured":"Bloom B, Bruno D, Maman D, Jayadevappa R. Usefulness of US cost-of-illness studies in healthcare decision making. PharmacoEconomics. 2001;19(2):207\u201313.","journal-title":"PharmacoEconomics"},{"key":"166_CR14","unstructured":"Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality (AHRQ). United States Nationwide Inpatient Sample 2012. Rockville, MD: Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality (AHRQ); 2012."},{"key":"166_CR15","unstructured":"Truven Health Analytics. United States MarketScan Medicare Supplemental and Coordination of Benefits Database 2010. Michigan, United States: Truven Health Analytics; 2010."},{"key":"166_CR16","unstructured":"Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality. Introduction to the HCUP National Inpatient Sample (NIS) 2012. Rockville, MD: Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality (AHRQ); 2012."},{"key":"166_CR17","unstructured":"Medicode (Firm). ICD-9-CM: International classification of diseases, 9th revision, clinical modification. Salt Lake City, UT: Medicode (Firm); 1996."},{"issue":"9663","key":"166_CR18","first-page":"117","volume":"385","author":"GBD 2013 Mortality and Causes of Death Collaborators","year":"2014","unstructured":"GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the global burden of disease study 2013. Lancet. 2014 Dec;385(9663):117\u201371.","journal-title":"Lancet"},{"key":"166_CR19","unstructured":"Druss BG, Walker ER. Mental Disorders and medical Comorbidity. Robert Wood Johnson Foundation; 2011 Feb. (The Synthesis Project: New Insights from Research Results). Report No.: Research Synthesis Report No. 21."},{"issue":"10","key":"166_CR20","doi-asserted-by":"publisher","first-page":"e76013","DOI":"10.1371\/journal.pone.0076013","volume":"8","author":"AG Ording","year":"2013","unstructured":"Ording AG, Garne JP, Nystrom PM, Froslev T, Sorenson HT, Lash TL. Comorbid diseases interact with breast cancer to affect mortality in the first year after diagnosis - a Danish Nationwide matched cohort study. PLoS One. 2013;8(10):e76013.","journal-title":"PLoS One"}],"container-title":["Health Economics Review"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13561-017-0166-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13561-017-0166-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13561-017-0166-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T10:12:02Z","timestamp":1561371122000},"score":1,"resource":{"primary":{"URL":"https:\/\/healtheconomicsreview.biomedcentral.com\/articles\/10.1186\/s13561-017-0166-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,29]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["166"],"URL":"https:\/\/doi.org\/10.1186\/s13561-017-0166-2","relation":{},"ISSN":["2191-1991"],"issn-type":[{"value":"2191-1991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,29]]},"assertion":[{"value":"25 April 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not Applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not Applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"30"}}