{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T09:44:24Z","timestamp":1790502264504,"version":"4.1.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"EU FP7","award":["278976"],"award-info":[{"award-number":["278976"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Vet Res"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s13567-017-0430-9","type":"journal-article","created":{"date-parts":[[2017,4,12]],"date-time":"2017-04-12T03:38:46Z","timestamp":1491968326000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Permissiveness of bovine epithelial cells from lung, intestine, placenta and udder for infection with Coxiella burnetii"],"prefix":"10.1186","volume":"48","author":[{"given":"Katharina","family":"Sobotta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Bonkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Liebler-Tenorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Germon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Rainard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Hambruch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Pfarrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilse D.","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Menge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,4,12]]},"reference":[{"key":"430_CR1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1128\/CMR.12.4.518","volume":"12","author":"M Maurin","year":"1999","unstructured":"Maurin M, Raoult D (1999) Q fever. Clin Microbiol Rev 12:518\u2013553","journal-title":"Clin Microbiol Rev"},{"key":"430_CR2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1051\/vetres:2005010","volume":"36","author":"N Arricau-Bouvery","year":"2005","unstructured":"Arricau-Bouvery N, Rodolakis A (2005) Is Q fever an emerging or re-emerging zoonosis? Vet Res 36:327\u2013349","journal-title":"Vet Res"},{"key":"430_CR3","volume-title":"Q fever: the disease","author":"GH Lang","year":"1990","unstructured":"Lang GH (1990) Coxiellosis (Q fever) in animals. In: Marrie TJ (ed) Q fever: the disease, vol 1. CRC Press, New York"},{"key":"430_CR4","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1136\/vr.148.16.502","volume":"148","author":"M Berri","year":"2001","unstructured":"Berri M, Souriau A, Crosby M, Crochet D, Lechopier P, Rodolakis A (2001) Relationships between the shedding of Coxiella burnetii, clinical signs and serological responses of 34 sheep. Vet Rec 148:502\u2013505","journal-title":"Vet Rec"},{"key":"430_CR5","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.3201\/eid1007.030724","volume":"10","author":"H Tissot-Dupont","year":"2004","unstructured":"Tissot-Dupont H, Amadei MA, Nezri M, Raoult D (2004) Wind in November, Q fever in December. Emerg Infect Dis 10:1264\u20131269","journal-title":"Emerg Infect Dis"},{"key":"430_CR6","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/978-94-007-4315-1_17","volume":"984","author":"W Hoek van der","year":"2012","unstructured":"van der Hoek W, Morroy G, Renders NHM, Wever PC, Hermans MHA, Leenders ACAP, Schneeberger PM (2012) Epidemic Q fever in humans in the Netherlands. Adv Exp Med Biol 984:329\u2013364","journal-title":"Adv Exp Med Biol"},{"key":"430_CR7","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jcpa.2006.06.003","volume":"135","author":"J S\u00e1nchez","year":"2006","unstructured":"S\u00e1nchez J, Souriau A, Buend\u00eda AJ, Arricau-Bouvery N, Mart\u00ednez CM, Salinas J, Rodolakis A, Navarro JA (2006) Experimental Coxiella burnetii infection in pregnant goats: a histopathological and immunohistochemical study. J Comp Pathol 135:108\u2013115","journal-title":"J Comp Pathol"},{"key":"430_CR8","doi-asserted-by":"crossref","first-page":"e48949","DOI":"10.1371\/journal.pone.0048949","volume":"7","author":"HJ Roest","year":"2012","unstructured":"Roest HJ, van Gelderen B, Dinkla A, Frangoulidis D, van Zijderveld F, Rebel J, van Keulen L (2012) Q fever in pregnant goats: pathogenesis and excretion of Coxiella burnetii. PLoS One 7:e48949","journal-title":"PLoS One"},{"key":"430_CR9","doi-asserted-by":"crossref","first-page":"5352","DOI":"10.3168\/jds.2006-815","volume":"90","author":"A Rodolakis","year":"2007","unstructured":"Rodolakis A, Berri M, H\u00e9chard C, Caudron C, Souriau A, Bodier CC, Blanchard B, Camuset P, Devillechaise P, Natorp JC, Vadet JP, Arricau-Bouvery N (2007) Comparison of Coxiella burnetii shedding in milk of dairy bovine, caprine, and ovine herds. J Dairy Sci 90:5352\u20135360","journal-title":"J Dairy Sci"},{"key":"430_CR10","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1051\/vetres:2007038","volume":"38","author":"R Guatteo","year":"2007","unstructured":"Guatteo R, Beaudeau F, Joly A, Seegers H (2007) Coxiella burnetii shedding by dairy cows. Vet Res 38:12","journal-title":"Vet Res"},{"key":"430_CR11","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1136\/vr.100908","volume":"171","author":"GE Valergakis","year":"2012","unstructured":"Valergakis GE, Russell C, Grogono-Thomas R, Bradley AJ, Eisler MC (2012) Coxiella burnetii in bulk tank milk of dairy cattle in south-west England. Vet Rec 171:156","journal-title":"Vet Rec"},{"key":"430_CR12","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1136\/vr.c6106","volume":"168","author":"J Muskens","year":"2011","unstructured":"Muskens J, van Engelen E, van Maanen C, Bartels C, Lam TJGM (2011) Prevalence of Coxiella burnetii infection in Dutch dairy herds based on testing bulk tank milk and individual samples by PCR and ELISA. Vet Rec 168:79","journal-title":"Vet Rec"},{"key":"430_CR13","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1128\/IAI.01208-15","volume":"84","author":"K Sobotta","year":"2016","unstructured":"Sobotta K, Hillarius K, Mager M, Kerner K, Heydel C, Menge C (2016) Coxiella burnetii infects primary bovine macrophages and limits their host cell response. Infect Immun 84:1722\u20131734","journal-title":"Infect Immun"},{"key":"430_CR14","doi-asserted-by":"crossref","first-page":"3104","DOI":"10.1128\/IAI.00042-15","volume":"83","author":"A Elliott","year":"2015","unstructured":"Elliott A, Schoenlaub L, Freches D, Mitchell W, Zhang G (2015) Neutrophils play an important role in protective immunity against Coxiella burnetii infection. Infect Immun 83:3104\u20133113","journal-title":"Infect Immun"},{"key":"430_CR15","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1128\/IAI.56.7.1792-1799.1988","volume":"56","author":"T Khavkin","year":"1988","unstructured":"Khavkin T, Tabibzadeh SS (1988) Histologic, immunofluorescence, and electron microscopic study of infectious process in mouse lung after intranasal challenge with Coxiella burnetii. Infect Immun 56:1792\u20131799","journal-title":"Infect Immun"},{"key":"430_CR16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0008-6215(96)87610-5","volume":"283","author":"R Toman","year":"1996","unstructured":"Toman R, \u0160kult\u00e9ty L (1996) Structural study on a lipopolysaccharide from Coxiella burnetii strain Nine Mile in avirulent phase II. Carbohydr Res 283:175\u2013185","journal-title":"Carbohydr Res"},{"key":"430_CR17","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s13567-015-0201-4","volume":"46","author":"P Roussel","year":"2015","unstructured":"Roussel P, Cunha P, Porcherie A, Petzl W, Gilbert FB, Riollet C, Zerbe H, Rainard P, Germon P (2015) Investigating the contribution of IL-17A and IL-17F to the host response during Escherichia coli mastitis. Vet Res 46:56","journal-title":"Vet Res"},{"key":"430_CR18","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1128\/IAI.01487-05","volume":"74","author":"S Goellner","year":"2006","unstructured":"Goellner S, Schubert E, Liebler-Tenorio E, Hotzel H, Saluz HP, Sachse K (2006) Transcriptional response patterns of Chlamydophila psittaci in different in vitro models of persistent infection. Infect Immun 74:4801\u20134808","journal-title":"Infect Immun"},{"key":"430_CR19","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2180-6-2","volume":"6","author":"SR Klee","year":"2006","unstructured":"Klee SR, Tyczka J, Ellerbrok H, Franz T, Linke S, Baljer G, Appel B (2006) Highly sensitive real-time PCR for specific detection and quantification of Coxiella burnetii. BMC Microbiol 6:2","journal-title":"BMC Microbiol"},{"key":"430_CR20","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1093\/nar\/30.9.e36","volume":"30","author":"MW Pfaffl","year":"2002","unstructured":"Pfaffl MW, Horgan GW, Dempfle L (2002) Relative expression software tool (REST\u00a9) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:e36","journal-title":"Nucleic Acids Res"},{"key":"430_CR21","doi-asserted-by":"crossref","first-page":"6078","DOI":"10.4049\/jimmunol.163.11.6078","volume":"163","author":"C Capo","year":"1999","unstructured":"Capo C, Lindberg FP, Meconi S, Zaffran Y, Tardei G, Brown EJ, Raoult D, Mege JL (1999) Subversion of monocyte functions by Coxiella burnetii: impairment of the cross-talk between \u03b1v\u03b23 integrin and CR3. J Immunol 163:6078\u20136085","journal-title":"J Immunol"},{"key":"430_CR22","doi-asserted-by":"crossref","first-page":"4263","DOI":"10.1128\/IAI.00594-07","volume":"75","author":"DE Voth","year":"2007","unstructured":"Voth DE, Howe D, Heinzen RA (2007) Coxiella burnetii inhibits apoptosis in human THP-1 cells and monkey primary alveolar macrophages. Infect Immun 75:4263\u20134271","journal-title":"Infect Immun"},{"key":"430_CR23","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1751-0147-55-13","volume":"55","author":"JS Agerholm","year":"2013","unstructured":"Agerholm JS (2013) Coxiella burnetii associated reproductive disorders in domestic animals\u2014a critical review. Acta Vet Scand 55:13","journal-title":"Acta Vet Scand"},{"key":"430_CR24","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/BF01647731","volume":"15","author":"DID Aitken","year":"1987","unstructured":"Aitken DID, B\u00f6gel DK, Cracea PDE, Edlinger E, Houwers DD, Krauss PDH, R\u00e1dy DM, Reh\u00e1cek DJ, Schiefer PDHG, Kaz\u00e1n DJ, Schmeer DN, Tarasevich PDIV, Tringali PDG (1987) Q fever in Europe: current aspects of aetiology, epidemiology, human infection, diagnosis and therapy. Infection 15:323\u2013327","journal-title":"Infection"},{"key":"430_CR25","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.2460\/ajvr.1974.35.12.1577","volume":"35","author":"EL Biberstein","year":"1974","unstructured":"Biberstein EL, Behymer DE, Bushnell R, Crenshaw G, Riemann HP, Franti CE (1974) A survey of Q fever (Coxiella burnetii) in California dairy cows. Am J Vet Res 35:1577\u20131582","journal-title":"Am J Vet Res"},{"key":"430_CR26","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1111\/jam.12778","volume":"118","author":"P Gale","year":"2015","unstructured":"Gale P, Kelly L, Mearns R, Duggan J, Snary EL (2015) Q fever through consumption of unpasteurised milk and milk products\u2014a risk profile and exposure assessment. J Appl Microbiol 118:1083\u20131095","journal-title":"J Appl Microbiol"},{"key":"430_CR27","doi-asserted-by":"crossref","first-page":"707","DOI":"10.2307\/4591908","volume":"78","author":"WW Benson","year":"1963","unstructured":"Benson WW, Brock DW, Mather J (1963) Serologic analysis of a penitentiary group using raw milk from a Q fever infected herd. Public Health Rep 78:707\u2013710","journal-title":"Public Health Rep"},{"key":"430_CR28","doi-asserted-by":"crossref","first-page":"695","DOI":"10.2105\/AJPH.47.6.695","volume":"47","author":"JB Enright","year":"1957","unstructured":"Enright JB, Sadler WW, Thomas RC (1957) Pasteurization of milk containing the organism of Q fever. Am J Public Health Nations Health 47:695\u2013700","journal-title":"Am J Public Health Nations Health"},{"key":"430_CR29","first-page":"411","volume":"89","author":"EH Schaal","year":"1982","unstructured":"Schaal EH (1982) Udder colonization with Coxiella burnetii in cattle Q fever. Dtsch Tierarztl Wochenschr 89:411\u2013414 (in German)","journal-title":"Dtsch Tierarztl Wochenschr"},{"key":"430_CR30","doi-asserted-by":"crossref","first-page":"7344","DOI":"10.1128\/JB.186.21.7344-7352.2004","volume":"186","author":"SA Coleman","year":"2004","unstructured":"Coleman SA, Fischer ER, Howe D, Mead DJ, Heinzen RA (2004) Temporal analysis of Coxiella burnetii morphological differentiation. J Bacteriol 186:7344\u20137352","journal-title":"J Bacteriol"},{"key":"430_CR31","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/nrmicro3049","volume":"11","author":"EJ Schaik van","year":"2013","unstructured":"van Schaik EJ, Chen C, Mertens K, Weber MM, Samuel JE (2013) Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii. Nat Rev Microbiol 11:561\u2013573","journal-title":"Nat Rev Microbiol"},{"key":"430_CR32","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1046\/j.1462-5822.2003.00293.x","volume":"5","author":"D Howe","year":"2003","unstructured":"Howe D, Melnic\u00e1kov\u00e1 J, Bar\u00e1k I, Heinzen RA (2003) Maturation of the Coxiella burnetii parasitophorous vacuole requires bacterial protein synthesis but not replication. Cell Microbiol 5:469\u2013480","journal-title":"Cell Microbiol"},{"key":"430_CR33","doi-asserted-by":"crossref","first-page":"4609","DOI":"10.1128\/IAI.00301-09","volume":"77","author":"M Aguilera","year":"2009","unstructured":"Aguilera M, Salinas R, Rosales E, Carminati S, Colombo MI, Ber\u00f3n W (2009) Actin dynamics and Rho GTPases regulate the size and formation of parasitophorous vacuoles containing Coxiella burnetii. Infect Immun 77:4609\u20134620","journal-title":"Infect Immun"},{"key":"430_CR34","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0021-9975(08)80254-X","volume":"109","author":"P Moll van","year":"1993","unstructured":"van Moll P, Baumg\u00e4rtner W, Eskens U, H\u00e4nichen T (1993) Immunocytochemical demonstration of Coxiella burnetii antigen in the fetal placenta of naturally infected sheep and cattle. J Comp Pathol 109:295\u2013301","journal-title":"J Comp Pathol"},{"key":"430_CR35","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.placenta.2007.07.002","volume":"28","author":"PS Bridger","year":"2007","unstructured":"Bridger PS, Menge C, Leiser R, Tinneberg HR, Pfarrer CD (2007) Bovine caruncular epithelial cell line (BCEC-1) isolated from the placenta forms a functional epithelial barrier in a polarised cell culture model. Placenta 28:1110\u20131117","journal-title":"Placenta"},{"key":"430_CR36","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.placenta.2009.10.011","volume":"31","author":"N Hambruch","year":"2010","unstructured":"Hambruch N, Haeger JD, Dilly M, Pfarrer C (2010) EGF stimulates proliferation in the bovine placental trophoblast cell line F3 via Ras and MAPK. Placenta 31:67\u201374","journal-title":"Placenta"},{"key":"430_CR37","doi-asserted-by":"crossref","first-page":"7253","DOI":"10.1128\/AEM.02180-15","volume":"81","author":"A Jouli\u00e9","year":"2015","unstructured":"Jouli\u00e9 A, Laroucau K, Bailly X, Prigent M, Gasqui P, Lepetitcolin E, Blanchard B, Rousset E, Sidi-Boumedine K, Jourdain E (2015) Coxiella burnetii circulation in a naturally infected flock of dairy sheep: shedding dynamics, environmental contamination, and genotype diversity. Appl Environ Microbiol 81:7253\u20137260","journal-title":"Appl Environ Microbiol"},{"key":"430_CR38","doi-asserted-by":"crossref","first-page":"e51941","DOI":"10.1371\/journal.pone.0051941","volume":"7","author":"M Calverley","year":"2012","unstructured":"Calverley M, Erickson S, Read AJ, Harmsen AG (2012) Resident alveolar macrophages are susceptible to and permissive of Coxiella burnetii infection. PLoS One 7:e51941","journal-title":"PLoS One"},{"key":"430_CR39","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1111\/cmi.12096","volume":"15","author":"JG Graham","year":"2013","unstructured":"Graham JG, MacDonald LJ, Hussain SK, Sharma UM, Kurten RC, Voth DE (2013) Virulent Coxiella burnetii pathotypes productively infect primary human alveolar macrophages. Cell Microbiol 15:1012\u20131025","journal-title":"Cell Microbiol"},{"key":"430_CR40","first-page":"143","volume":"37","author":"OG Baca","year":"1993","unstructured":"Baca OG, Klassen DA, Aragon AS (1993) Entry of Coxiella burnetii into host cells. Acta Virol 37:143\u2013155","journal-title":"Acta Virol"},{"key":"430_CR41","doi-asserted-by":"crossref","first-page":"e1004013","DOI":"10.1371\/journal.ppat.1004013","volume":"10","author":"E Martinez","year":"2014","unstructured":"Martinez E, Cantet F, Fava L, Norville I, Bonazzi M (2014) Identification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic high-content screening. PLoS Pathog 10:e1004013","journal-title":"PLoS Pathog"},{"key":"430_CR42","doi-asserted-by":"crossref","first-page":"5673","DOI":"10.1128\/IAI.68.10.5673-5678.2000","volume":"68","author":"J Dellacasagrande","year":"2000","unstructured":"Dellacasagrande J, Ghigo E, Machergui-El S, Hammami Toman R, Raoult D, Capo C, Mege JL (2000) \u03b1v\u03b23 integrin and bacterial lipopolysaccharide are involved in Coxiella burnetii-stimulated production of tumor necrosis factor by human monocytes. Infect Immun 68:5673\u20135678","journal-title":"Infect Immun"},{"key":"430_CR43","doi-asserted-by":"crossref","first-page":"54405","DOI":"10.1074\/jbc.M410340200","volume":"279","author":"DS Zamboni","year":"2004","unstructured":"Zamboni DS, Campos MA, Torrecilhas ACT, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT (2004) Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. J Biol Chem 279:54405\u201354415","journal-title":"J Biol Chem"},{"key":"430_CR44","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1172\/JCI119136","volume":"99","author":"SJ Rasmussen","year":"1997","unstructured":"Rasmussen SJ, Eckmann L, Quayle AJ, Shen L, Zhang YX, Anderson DJ, Fierer J, Stephens RS, Kagnoff MF (1997) Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. J Clin Investig 99:77\u201387","journal-title":"J Clin Investig"},{"key":"430_CR45","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1172\/JCI117676","volume":"95","author":"HC Jung","year":"1995","unstructured":"Jung HC, Eckmann L, Yang SK, Panja A, Fierer J, Morzycka-Wroblewska E, Kagnoff MF (1995) A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Investig 95:55\u201365","journal-title":"J Clin Investig"},{"key":"430_CR46","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1080\/21505594.2015.1012981","volume":"6","author":"DL Moyes","year":"2015","unstructured":"Moyes DL, Richardson JP, Naglik JR (2015) Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface. Virulence 6:338\u2013346","journal-title":"Virulence"},{"key":"430_CR47","doi-asserted-by":"crossref","first-page":"e15315","DOI":"10.1371\/journal.pone.0015315","volume":"5","author":"A Ben Amara","year":"2010","unstructured":"Ben Amara A, Ghigo E, Le Priol Y, L\u00e9polard C, Salcedo SP, Lemichez E, Bretelle F, Capo C, Mege JL (2010) Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response. PLoS One 5:e15315","journal-title":"PLoS One"},{"key":"430_CR48","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/1471-2180-14-41","volume":"14","author":"T Pearson","year":"2014","unstructured":"Pearson T, Hornstra HM, Hilsabeck R, Gates LT, Olivas SM, Birdsell DM, Hall CM, German S, Cook JM, Seymour ML, Priestley RA, Kondas AV, Clark Friedman CL, Price EP, Schupp JM, Liu CM, Price LB, Massung RF, Kersh GJ, Keim P (2014) High prevalence and two dominant host-specific genotypes of Coxiella burnetii in U.S. milk. BMC Microbiol 14:41","journal-title":"BMC Microbiol"}],"container-title":["Veterinary Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13567-017-0430-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T21:58:05Z","timestamp":1750197485000},"score":1,"resource":{"primary":{"URL":"http:\/\/veterinaryresearch.biomedcentral.com\/articles\/10.1186\/s13567-017-0430-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,12]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["430"],"URL":"https:\/\/doi.org\/10.1186\/s13567-017-0430-9","relation":{},"ISSN":["1297-9716"],"issn-type":[{"value":"1297-9716","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,12]]},"article-number":"23"}}