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Vaccine <jats:italic>B. melitensis<\/jats:italic> Rev1 is used against <jats:italic>B. melitensis<\/jats:italic> and <jats:italic>B. ovis<\/jats:italic> but induces an anti-smooth-lipopolysaccharide response interfering with <jats:italic>B. melitensis<\/jats:italic> serodiagnosis, which precludes its use against <jats:italic>B. ovis<\/jats:italic> where <jats:italic>B. melitensis<\/jats:italic> is absent. 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Mu\ufffd\ufffdoz and Raquel Conde\ufffd\ufffd\ufffdAlvarez contributed equally to this work.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Studies in mice were done\u00a0in accordance with the current European (directive 86\/609\/EEC) and Spanish (RD 53\/2013) legislations, supervised by both Ethical Committee for Animal Experimentation of CITA and Animal Welfare Committee of the University of Navarra and authorised by Arag\u00f3n (reports No. 2014-20 and 2014-21) and Navarra (CEEA 045\/12) Governments.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"95"}}