{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:11:12Z","timestamp":1790831472206,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"vor","delay-in-days":3244,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Intensive Care"],"published-print":{"date-parts":[[2017]]},"DOI":"10.1186\/s13613-017-0315-0","type":"journal-article","created":{"date-parts":[[2017,9,12]],"date-time":"2017-09-12T08:43:39Z","timestamp":1505205819000},"page":"97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"title":["High level of venous thromboembolism in critically ill trauma patients despite early and well-driven thromboprophylaxis protocol"],"prefix":"10.1016","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8405-5997","authenticated-orcid":false,"given":"S.R.","family":"Hamada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Espina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Guedj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Buaron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Harrois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Duranteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1186\/s13613-017-0315-0_bb0010","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s12028-015-0221-y","article-title":"Prophylaxis of venous thrombosis in neurocritical care patients: an evidence-based guideline: A Statement for Healthcare Professionals from the Neurocritical Care Society","volume":"24","author":"Nyquist","year":"2016","journal-title":"Neurocrit Care"},{"key":"10.1186\/s13613-017-0315-0_bb0015","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S1072-7515(98)00082-9","article-title":"Lethal injuries and time to death in a level I trauma center","volume":"186","author":"Acosta","year":"1998","journal-title":"J Am Coll Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0020","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1072-7515(00)00802-4","article-title":"A potentially expanded role for enoxaparin in preventing venous thromboembolism in high risk blunt trauma patients","volume":"192","author":"Norwood","year":"2001","journal-title":"J Am Coll Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0025","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/00005373-199201000-00002","article-title":"Thromboembolism following multiple trauma","volume":"32","author":"Knudson","year":"1992","journal-title":"J Trauma"},{"key":"10.1186\/s13613-017-0315-0_bb0030","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.clineuro.2014.05.017","article-title":"Chemoprophylaxis for venous thromboembolism in traumatic brain injury: a review and evidence-based protocol","volume":"123","author":"Foreman","year":"2014","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1186\/s13613-017-0315-0_bb0035","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/TA.0b013e318265cab9","article-title":"Is low-molecular-weight heparin safe for venous thromboembolism prophylaxis in patients with traumatic brain injury? A Western Trauma Association multicenter study","volume":"73","author":"Kwiatt","year":"2012","journal-title":"J. Trauma Acute Care Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0040","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1067\/msy.2000.108224","article-title":"The risk assessment profile score identifies trauma patients at risk for deep vein thrombosis","volume":"128","author":"Gearhart","year":"2000","journal-title":"Surgery"},{"key":"10.1186\/s13613-017-0315-0_bb0045","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/00005373-200207000-00032","article-title":"Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group","volume":"53","author":"Rogers","year":"2002","journal-title":"J Trauma Acute Care Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0050","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1365-2141.2008.07323.x","article-title":"Virchow and his triad: a question of attribution","volume":"143","author":"Bagot","year":"2008","journal-title":"Br J Haematol"},{"key":"10.1186\/s13613-017-0315-0_bb0055","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1097\/01.sla.0000256862.79374.31","article-title":"Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?","volume":"245","author":"Brohi","year":"2007","journal-title":"Ann Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0060","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s002689900001","article-title":"Hypercoagulability following multiple trauma","volume":"20","author":"Engelman","year":"1996","journal-title":"World J Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0065","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.thromres.2008.10.002","article-title":"Hypercoagulability after trauma: hemostatic changes and relationship to venous thromboembolism","volume":"124","author":"Selby","year":"2009","journal-title":"Thromb Res"},{"key":"10.1186\/s13613-017-0315-0_bb0070","doi-asserted-by":"crossref","first-page":"R147","DOI":"10.1186\/cc13982","article-title":"Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational study of trauma patients","volume":"18","author":"Sch\u00f6chl","year":"2014","journal-title":"Crit Care Lond Engl"},{"key":"10.1186\/s13613-017-0315-0_bb0075","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/TA.0000000000000108","article-title":"Fibrinogen and platelet contributions to clot formation: implications for trauma resuscitation and thromboprophylaxis","volume":"76","author":"Kornblith","year":"2014","journal-title":"J Trauma Acute Care Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0080","doi-asserted-by":"crossref","unstructured":"Barrera LM, Perel P, Ker K, Cirocchi R, Farinella E, Morales Uribe CH. Thromboprophylaxis for trauma patients. Cochrane Database Syst Rev. 2013;(3):CD008303. doi:10.1002\/14651858.CD008303.pub2.","DOI":"10.1002\/14651858.CD008303.pub2"},{"key":"10.1186\/s13613-017-0315-0_bb0085","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/TA.0000000000001058","article-title":"Early antithrombotic therapy is safe and effective in patients with blunt cerebrovascular injury and solid organ injury or traumatic brain injury","volume":"81","author":"Shahan","year":"2016","journal-title":"J Trauma Acute Care Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0090","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/S0895-4356(01)00341-9","article-title":"Internal validation of predictive models: efficiency of some procedures for logistic regression analysis","volume":"54","author":"Steyerberg","year":"2001","journal-title":"J Clin Epidemiol"},{"issue":"153\u2013160","key":"10.1186\/s13613-017-0315-0_bb0095","first-page":"e3","article-title":"Development and validation of a necrotizing soft-tissue infection mortality risk calculator using NSQIP","volume":"217","author":"Faraklas","year":"2013","journal-title":"J Am Coll Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0100","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1046\/j.0007-1323.2001.01800.x","article-title":"Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery","volume":"88","author":"Mismetti","year":"2001","journal-title":"Br J Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0105","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1056\/NEJM199609053351003","article-title":"A comparison of low-dose heparin with low-molecular-weight heparin as prophylaxis against venous thromboembolism after major trauma","volume":"335","author":"Geerts","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1186\/s13613-017-0315-0_bb0110","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.jamcollsurg.2009.08.001","article-title":"Fondaparinux for prevention of venous thromboembolism in high-risk trauma patients: a pilot study","volume":"209","author":"Lu","year":"2009","journal-title":"J Am Coll Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0115","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/00005373-200007000-00021","article-title":"Prevention of venous thromboembolism after injury: an evidence-based report\u2014part II: analysis of risk factors and evaluation of the role of vena caval filters","volume":"49","author":"Velmahos","year":"2000","journal-title":"J Trauma"},{"key":"10.1186\/s13613-017-0315-0_bb0120","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1097\/CCM.0b013e31825bcb60","article-title":"Venous thromboembolism after trauma: a never event?*","volume":"40","author":"Thorson","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1186\/s13613-017-0315-0_bb0125","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1056\/NEJM199412153312401","article-title":"A prospective study of venous thromboembolism after major trauma","volume":"331","author":"Geerts","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1186\/s13613-017-0315-0_bb0130","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0002-9610(05)81272-3","article-title":"Venous thromboembolism in patients with major trauma","volume":"159","author":"Shackford","year":"1990","journal-title":"Am J Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/cc12748","article-title":"Subclavian central venous catheter-related thrombosis in trauma patients: incidence, risk factors and influence of polyurethane type","volume":"17","author":"Gentile","year":"2013","journal-title":"Crit Care"},{"key":"10.1186\/s13613-017-0315-0_bb0140","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1046\/j.1365-2044.2001.02058-2.x","article-title":"Prophylaxis against thromboembolism in patients with traumatic brain injury: a survey of UK practice","volume":"56","author":"Cupitt","year":"2001","journal-title":"Anaesthesia"},{"key":"10.1186\/s13613-017-0315-0_bb0145","doi-asserted-by":"crossref","first-page":"e162069","DOI":"10.1001\/jamasurg.2016.2069","article-title":"Thrombelastography-based dosing of enoxaparin for thromboprophylaxis in trauma and surgical patients: a randomized clinical trial","volume":"151","author":"Connelly","year":"2016","journal-title":"JAMA Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0150","first-page":"40","article-title":"Diagnosis of deep vein thrombosis in asymptomatic high-risk patients","volume":"25","author":"Agnelli","year":"1995","journal-title":"Haemostasis"},{"key":"10.1186\/s13613-017-0315-0_bb0155","doi-asserted-by":"crossref","first-page":"47","DOI":"10.7326\/0003-4819-122-1-199501010-00008","article-title":"Accuracy of ultrasound for the diagnosis of deep venous thrombosis in asymptomatic patients after orthopedic surgery. A meta-analysis","volume":"122","author":"Wells","year":"1995","journal-title":"Ann Intern Med"},{"key":"10.1186\/s13613-017-0315-0_bb0160","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0002-9610(05)81083-9","article-title":"Why does prophylaxis with external pneumatic compression for deep vein thrombosis fail?","volume":"164","author":"Comerota","year":"1992","journal-title":"Am J Surg"},{"key":"10.1186\/s13613-017-0315-0_bb0165","first-page":"994","article-title":"Predictors of posttraumatic deep vein thrombosis (DVT): hospital practice versus patient factors-an analysis of the National Trauma Data Bank (NTDB)","volume":"66","author":"Haut","year":"2009","journal-title":"J Trauma"},{"key":"10.1186\/s13613-017-0315-0_bb0170","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1001\/jama.286.6.700","article-title":"Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial","volume":"286","author":"Merrer","year":"2001","journal-title":"JAMA"},{"key":"10.1186\/s13613-017-0315-0_bb0175","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1177\/000313481508100923","article-title":"Standard dosing of enoxaparin for venous thromboembolism prophylaxis is not sufficient for most patients within a trauma intensive care unit","volume":"81","author":"Rostas","year":"2015","journal-title":"Am Surg"},{"issue":"11","key":"10.1186\/s13613-017-0315-0_bb0180","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1001\/jamasurg.2016.1662","article-title":"Association between enoxaparin dosage adjusted by anti-factor Xa trough level and clinically evident venous thromboembolism after trauma","volume":"151","author":"Ko","year":"2016","journal-title":"JAMA Surg"}],"container-title":["Annals of Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-017-0315-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13613-017-0315-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025019843?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025019843?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-017-0315-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T07:25:55Z","timestamp":1776669955000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2110582025019843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017]]}},"alternative-id":["S2110582025019843"],"URL":"https:\/\/doi.org\/10.1186\/s13613-017-0315-0","relation":{},"ISSN":["2110-5820"],"issn-type":[{"value":"2110-5820","type":"print"}],"subject":[],"published":{"date-parts":[[2017]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High level of venous thromboembolism in critically ill trauma patients despite early and well-driven thromboprophylaxis protocol","name":"articletitle","label":"Article Title"},{"value":"Annals of Intensive Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1186\/s13613-017-0315-0","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 The Author(s) 2017. Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}],"article-number":"97"}}