{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:41:30Z","timestamp":1790692890316,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"vor","delay-in-days":2149,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Intensive Care"],"published-print":{"date-parts":[[2020]]},"DOI":"10.1186\/s13613-020-00751-y","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T15:02:54Z","timestamp":1601996574000},"page":"131","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Characteristics and outcomes of acute respiratory distress syndrome related to COVID-19 in Belgian and French intensive care units according to antiviral strategies: the COVADIS multicentre observational study"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-065X","authenticated-orcid":false,"given":"David","family":"Grimaldi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Aissaoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gauthier","family":"Blonz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Carbutti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Courcelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Gaudry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelie","family":"Gaultier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"D\u2019hondt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Higny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Horlait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Hraiech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Lefebvre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Lejeune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Ly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Piagnerelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Sauneuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Serck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaud","family":"Soumagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Szychowiak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Textoris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Vandenbunder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Vinsonneau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean- Baptiste","family":"Lascarrou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Biston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwenhael","family":"Colin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriane","family":"de Maere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Ebstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Ehrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Foret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Haentjens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibault","family":"Helbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Baptiste","family":"Mesland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celine","family":"Monard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Mongardon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregoire","family":"Ottavy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Pasau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gael","family":"Piton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester","family":"Ponzetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Sejourne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgane","family":"Snacken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Souloy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aude","family":"Sylvestre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Tartrat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cedric","family":"Vanbrussel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10229","key":"10.1186\/s13613-020-00751-y_bb0010","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","article-title":"Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study","volume":"395","author":"Zhou","year":"2020","journal-title":"Lancet"},{"key":"10.1186\/s13613-020-00751-y_bb0015","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1056\/NEJMoa2002032","article-title":"Clinical characteristics of coronavirus disease 2019 in China","volume":"382","author":"Guan","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1186\/s13613-020-00751-y_bb0020","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1001\/jamainternmed.2020.0994","article-title":"Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China","volume":"180","author":"Wu","year":"2020","journal-title":"JAMA Intern Med"},{"key":"10.1186\/s13613-020-00751-y_bb0025","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.chest.2020.04.010","article-title":"Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a Nationwide Analysis in China","volume":"158","author":"Chen","year":"2020","journal-title":"Chest"},{"issue":"5","key":"10.1186\/s13613-020-00751-y_bb0030","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S2213-2600(20)30079-5","article-title":"Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study","volume":"8","author":"Yang","year":"2020","journal-title":"Lancet Respir Med"},{"issue":"5","key":"10.1186\/s13613-020-00751-y_bb0035","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1007\/s00134-020-06022-5","article-title":"Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19)","volume":"46","author":"Alhazzani","year":"2020","journal-title":"Intensive Care Med"},{"issue":"24","key":"10.1186\/s13613-020-00751-y_bb0040","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1056\/NEJMoa2007016","article-title":"Compassionate Use of Remdesivir for Patients with Severe Covid-19","volume":"382","author":"Grein","year":"2020","journal-title":"N Engl J Med"},{"issue":"19","key":"10.1186\/s13613-020-00751-y_bb0045","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1056\/NEJMoa2001282","article-title":"A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19","volume":"382","author":"Cao","year":"2020","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1186\/s13613-020-00751-y_bb0050","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S2213-2600(20)30172-7","article-title":"Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base","volume":"8","author":"Taccone","year":"2020","journal-title":"Lancet Respir Med"},{"key":"10.1186\/s13613-020-00751-y_bb0055","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa2007764","article-title":"Remdesivir for the treatment of Covid-19\u2014preliminary report","author":"Beigel","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1186\/s13613-020-00751-y_bb0060","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/S0140-6736(20)31042-4","article-title":"Triple combination of interferon beta-1b, lopinavir\u2013ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial","volume":"395","author":"Hung","year":"2020","journal-title":"Lancet"},{"issue":"9596","key":"10.1186\/s13613-020-00751-y_bb0065","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"10.1186\/s13613-020-00751-y_bb0070","unstructured":"The A.D.T.F., Acute respiratory distress syndrome: the Berlin definition.JAMA. 307(23): 2526\u20132533."},{"issue":"5","key":"10.1186\/s13613-020-00751-y_bb0075","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chronic Dis"},{"issue":"8","key":"10.1186\/s13613-020-00751-y_bb0080","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1097\/00003246-200208000-00016","article-title":"Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome","volume":"30","author":"Schoenfeld","year":"2002","journal-title":"Crit Care Med"},{"issue":"5","key":"10.1186\/s13613-020-00751-y_bb0085","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1053\/j.ajkd.2013.03.003","article-title":"Definition and classification of kidney diseases","volume":"61","author":"Levey","year":"2013","journal-title":"Am J Kidney Dis"},{"issue":"12","key":"10.1186\/s13613-020-00751-y_bb0090","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1164\/rccm.202004-1163LE","article-title":"Respiratory Pathophysiology of mechanically ventilated patients with COVID-19: A Cohort Study","volume":"201","author":"Ziehr","year":"2020","journal-title":"Am J RespirCrit Care Med"},{"issue":"8","key":"10.1186\/s13613-020-00751-y_bb0095","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jama.2016.0291","article-title":"Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries","volume":"315","author":"Bellani","year":"2016","journal-title":"JAMA"},{"issue":"1","key":"10.1186\/s13613-020-00751-y_bb0100","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s13613-019-0540-9","article-title":"Formal guidelines: management of acute respiratory distress syndrome","volume":"9","author":"Papazian","year":"2019","journal-title":"Ann Intensiv Care"},{"issue":"1","key":"10.1186\/s13613-020-00751-y_bb0105","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1186\/s13054-020-03164-2","article-title":"Neuromuscular blocking agents (NMBA) for COVID-19 acute respiratory distress syndrome: a multicenter observational study","volume":"24","author":"on behalf the COVADIS study group","year":"2020","journal-title":"Crit Care."},{"key":"10.1186\/s13613-020-00751-y_bb0110","doi-asserted-by":"crossref","DOI":"10.1056\/NEJMoa2019014","article-title":"Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19","author":"Cavalcanti","year":"2020","journal-title":"N Engl J Med"},{"issue":"24","key":"10.1186\/s13613-020-00751-y_bb0115","doi-asserted-by":"crossref","first-page":"2493","DOI":"10.1001\/jama.2020.8630","article-title":"Treatment With hydroxychloroquine or azithromycin with in-hospital mortality in patients with COVID-19 in New York State","volume":"323","author":"Rosenberg","year":"2020","journal-title":"JAMA"},{"key":"10.1186\/s13613-020-00751-y_bb0120","article-title":"Dexamethasone in hospitalized patients with Covid-19\u2014preliminary report","author":"RECOVERY Collaborative Group","year":"2020","journal-title":"N Engl J Med"},{"key":"10.1186\/s13613-020-00751-y_bb0125","unstructured":"IDSA. https:\/\/www.idsociety.org\/public-health\/COVID-19-Resource-Center\/."},{"key":"10.1186\/s13613-020-00751-y_bb0130","unstructured":"NIH. https:\/\/www.covid19treatmentguidelines.nih.gov\/antiviral-therapy\/."},{"key":"10.1186\/s13613-020-00751-y_bb0135","unstructured":"HCSP. https:\/\/www.hcsp.fr\/explore.cgi\/avisrapportsdomaine?clefr=866."},{"issue":"21","key":"10.1186\/s13613-020-00751-y_bb0140","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1001\/jama.284.21.2687","article-title":"A piece of my mind: the harm of \"first, do no harm\"","volume":"284","author":"Shelton","year":"2000","journal-title":"JAMA"},{"issue":"1","key":"10.1186\/s13613-020-00751-y_bb0145","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1016\/S2352-3018(15)00211-8","article-title":"Cumulative and current exposure to potentially nephrotoxicantiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study","volume":"3","author":"Mocroft","year":"2016","journal-title":"Lancet HIV"},{"issue":"1","key":"10.1186\/s13613-020-00751-y_bb0150","first-page":"60","article-title":"Ritonavir-induced acute kidney injury: kidney biopsy findings and review of literature","volume":"75","author":"Shafi","year":"2011","journal-title":"ClinNephrol"},{"issue":"1","key":"10.1186\/s13613-020-00751-y_bb0155","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.kint.2020.04.003","article-title":"Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China","volume":"98","author":"Su","year":"2020","journal-title":"Kidney Int"},{"issue":"5","key":"10.1186\/s13613-020-00751-y_bb0160","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.kint.2020.03.005","article-title":"Kidney disease is associated with in-hospital death of patients with COVID-19","volume":"97","author":"Cheng","year":"2020","journal-title":"Kidney Int"},{"issue":"9","key":"10.1186\/s13613-020-00751-y_bb0165","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1097\/CCM.0000000000003832","article-title":"Impact of early acute kidney injury on management and outcome in patients with acute respiratory distress syndrome: a secondary analysis of a Multicenter Observational Study","volume":"47","author":"McNicholas","year":"2019","journal-title":"Crit Care Med"},{"issue":"7","key":"10.1186\/s13613-020-00751-y_bb0170","first-page":"e0166","article-title":"Factors Associated with pulmonary embolism among coronavirus disease 2019 acute respiratory distress syndrome: A Multicenter Study among 375 patients","volume":"2","author":"Soumagne","year":"2020","journal-title":"Crit Care Explor"},{"issue":"6","key":"10.1186\/s13613-020-00751-y_bb0175","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1007\/s00134-020-06026-1","article-title":"Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis","volume":"46","author":"Pan","year":"2020","journal-title":"Intensive Care Med."},{"key":"10.1186\/s13613-020-00751-y_bb0180","first-page":"2702","article-title":"Lopinavir pharmacokinetics in COVID-19 patients","volume":"75","author":"Gregoire","year":"2020","journal-title":"J AntimicrobChemother"},{"key":"10.1186\/s13613-020-00751-y_bb0185","first-page":"2657","article-title":"Pharmacokinetics of lopinavir\/ritonavir oral solution to treat COVID-19 in mechanically ventilated ICU patients","volume":"75","author":"L\u00ea","year":"2020","journal-title":"J AntimicrobChemother"},{"key":"10.1186\/s13613-020-00751-y_bb0190","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S2213-2600(20)30316-7","article-title":"Case characteristics, resource use, and outcomes of 10,021 patients with COVID-19 admitted to 920 German hospitals: an observational study","volume":"8","author":"Karagiannidis","year":"2020","journal-title":"Lancet Respir Med"},{"key":"10.1186\/s13613-020-00751-y_bb0195","first-page":"203","article-title":"Comparison of Charlsoncomorbidity index with SAPS and APACHE scores for prediction of mortality following intensive care","volume":"3","author":"Christensen","year":"2011","journal-title":"ClinEpidemiol"},{"key":"10.1186\/s13613-020-00751-y_bb0200","doi-asserted-by":"crossref","DOI":"10.1007\/s00134-020-06192-2","article-title":"Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS","author":"Ferrando","year":"2020","journal-title":"Intensive Care Med"},{"issue":"3","key":"10.1186\/s13613-020-00751-y_bb0205","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/CCM.0000000000002890","article-title":"Ventilator-Free Day Outcomes Can Be Misleading","volume":"46","author":"Bodet-Contentin","year":"2018","journal-title":"Crit Care Med"}],"container-title":["Annals of Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-020-00751-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13613-020-00751-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025011720?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025011720?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-020-00751-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T07:37:54Z","timestamp":1776670674000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2110582025011720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020]]}},"alternative-id":["S2110582025011720"],"URL":"https:\/\/doi.org\/10.1186\/s13613-020-00751-y","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.06.28.20141911","asserted-by":"object"}]},"ISSN":["2110-5820"],"issn-type":[{"value":"2110-5820","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characteristics and outcomes of acute respiratory distress syndrome related to COVID-19 in Belgian and French intensive care units according to antiviral strategies: the COVADIS multicentre observational study","name":"articletitle","label":"Article Title"},{"value":"Annals of Intensive Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1186\/s13613-020-00751-y","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2020 The Author(s) 2020. Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}],"article-number":"131"}}