{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:44:55Z","timestamp":1792226695940,"version":"4.4.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"vor","delay-in-days":2149,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Intensive Care"],"published-print":{"date-parts":[[2020]]},"DOI":"10.1186\/s13613-020-0642-4","type":"journal-article","created":{"date-parts":[[2020,2,27]],"date-time":"2020-02-27T05:02:32Z","timestamp":1582779752000},"page":"26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Impact of corticosteroid treatment on clinical outcomes of influenza-associated ARDS: a nationwide multicenter study"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3621-3334","authenticated-orcid":false,"given":"Ming-Ju","family":"Tsai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuang-Yao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Cheng","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Chin","family":"Kao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Chien","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wann-Cherng","family":"Perng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh-Liang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinn-Jye","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Feng","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3222-0409","authenticated-orcid":false,"given":"Jong-Rung","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0049-5758","authenticated-orcid":false,"given":"Wei-An","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Chun","family":"Chien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Chih","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Chung","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiung-Yu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Cheng","family":"Chao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7979-3749","authenticated-orcid":false,"given":"Chau-Chyun","family":"Sheu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1186\/s13613-020-0642-4_bb0010","first-page":"CD010406","article-title":"Corticosteroids as adjunctive therapy in the treatment of influenza","volume":"2","author":"Lansbury","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1186\/s13613-020-0642-4_bb0015","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/infdis\/jiu645","article-title":"Effect of corticosteroid therapy on influenza-related mortality: a systematic review and meta-analysis","volume":"212","author":"Rodrigo","year":"2015","journal-title":"J Infect Dis"},{"issue":"1","key":"10.1186\/s13613-020-0642-4_bb0020","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/s13054-019-2491-9","article-title":"Influenza virus-related critical illness: prevention, diagnosis, treatment","volume":"23","author":"Chow","year":"2019","journal-title":"Crit Care"},{"issue":"10","key":"10.1186\/s13613-020-0642-4_bb0025","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/nm1477","article-title":"Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia","volume":"12","author":"de Jong","year":"2006","journal-title":"Nat Med"},{"issue":"2","key":"10.1186\/s13613-020-0642-4_bb0030","doi-asserted-by":"crossref","first-page":"R63","DOI":"10.1186\/cc13819","article-title":"Exploring the heterogeneity of effects of corticosteroids on acute respiratory distress syndrome: a systematic review and meta-analysis","volume":"18","author":"Ruan","year":"2014","journal-title":"Crit Care"},{"issue":"13","key":"10.1186\/s13613-020-0642-4_bb0035","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1056\/NEJMra052211","article-title":"Avian influenza A (H5N1) infection in humans","volume":"353","author":"Beigel","year":"2005","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1186\/s13613-020-0642-4_bb0040","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1164\/rccm.201101-0135OC","article-title":"Early corticosteroids in severe influenza A\/H1N1 pneumonia and acute respiratory distress syndrome","volume":"183","author":"Group R-SAHNvR","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1186\/s13613-020-0642-4_bb0045","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s13054-016-1230-8","article-title":"The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness","volume":"20","author":"Delaney","year":"2016","journal-title":"Crit Care"},{"issue":"6","key":"10.1186\/s13613-020-0642-4_bb0050","doi-asserted-by":"crossref","first-page":"e318","DOI":"10.1097\/CCM.0000000000001616","article-title":"Adjuvant corticosteroid treatment in adults with influenza A (H7N9) viral pneumonia","volume":"44","author":"Cao","year":"2016","journal-title":"Crit Care Med"},{"key":"10.1186\/s13613-020-0642-4_bb0055","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13054-015-0764-5","article-title":"Do corticosteroids reduce the mortality of influenza A (H1N1) infection? A meta-analysis","volume":"19","author":"Zhang","year":"2015","journal-title":"Crit Care."},{"issue":"12","key":"10.1186\/s13613-020-0642-4_bb0060","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s00134-018-5414-3","article-title":"Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study","volume":"44","author":"Moreno","year":"2018","journal-title":"Intensive Care Med"},{"issue":"10058","key":"10.1186\/s13613-020-0642-4_bb0065","doi-asserted-by":"crossref","first-page":"2416","DOI":"10.1016\/S0140-6736(16)00578-X","article-title":"Acute respiratory distress syndrome","volume":"388","author":"Sweeney","year":"2016","journal-title":"Lancet."},{"issue":"5","key":"10.1186\/s13613-020-0642-4_bb0070","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s00134-016-4327-2","article-title":"Adjuvants to mechanical ventilation for acute respiratory distress syndrome","volume":"42","author":"Munshi","year":"2016","journal-title":"Intensive Care Med"},{"issue":"5","key":"10.1186\/s13613-020-0642-4_bb0075","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1097\/CCM.0b013e31819fb507","article-title":"Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: a systematic review and meta-analysis","volume":"37","author":"Tang","year":"2009","journal-title":"Crit Care Med"},{"issue":"16","key":"10.1186\/s13613-020-0642-4_bb0080","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1056\/NEJMoa051693","article-title":"Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome","volume":"354","author":"Steinberg","year":"2006","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1186\/s13613-020-0642-4_bb0085","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1001\/jama.2016.0291","article-title":"Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries","volume":"315","author":"Bellani","year":"2016","journal-title":"JAMA"},{"issue":"1 Pt 2","key":"10.1186\/s13613-020-0642-4_bb0090","first-page":"378","article-title":"First tidal volume greater than 8\u00a0mL\/kg is associated with increased mortality in complicated influenza infection with acute respiratory distress syndrome","volume":"118","author":"Chan","year":"2018","journal-title":"J Formos Med Assoc"},{"issue":"1","key":"10.1186\/s13613-020-0642-4_bb0095","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s13613-018-0440-4","article-title":"Predictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning","volume":"8","author":"Kao","year":"2018","journal-title":"Ann Intensive Care."},{"issue":"1","key":"10.1186\/s13613-020-0642-4_bb0100","doi-asserted-by":"crossref","first-page":"e0190952","DOI":"10.1371\/journal.pone.0190952","article-title":"Association of day 4 cumulative fluid balance with mortality in critically ill patients with influenza: a multicenter retrospective cohort study in Taiwan","volume":"13","author":"Chao","year":"2018","journal-title":"PLoS ONE"},{"issue":"23","key":"10.1186\/s13613-020-0642-4_bb0105","first-page":"2526","article-title":"Acute respiratory distress syndrome: the Berlin definition","volume":"307","author":"Force","year":"2012","journal-title":"JAMA"},{"key":"10.1186\/s13613-020-0642-4_bb0110","author":"WHO","year":"2010"},{"issue":"7","key":"10.1186\/s13613-020-0642-4_bb0115","doi-asserted-by":"crossref","first-page":"519","DOI":"10.7326\/M15-0715","article-title":"Corticosteroid therapy for patients hospitalized with community-acquired pneumonia: a systematic review and meta-analysis","volume":"163","author":"Siemieniuk","year":"2015","journal-title":"Ann Intern Med"},{"issue":"9977","key":"10.1186\/s13613-020-0642-4_bb0120","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1016\/S0140-6736(14)62447-8","article-title":"Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial","volume":"385","author":"Blum","year":"2015","journal-title":"Lancet."},{"issue":"2","key":"10.1186\/s13613-020-0642-4_bb0125","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/cc2374","article-title":"Clinical review: corticotherapy in sepsis","volume":"8","author":"Prigent","year":"2004","journal-title":"Crit Care"},{"issue":"2","key":"10.1186\/s13613-020-0642-4_bb0130","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s00134-007-0868-8","article-title":"Stress doses of hydrocortisone in septic shock: beneficial effects on opsonization-dependent neutrophil functions","volume":"34","author":"Kaufmann","year":"2008","journal-title":"Intensive Care Med"},{"issue":"16","key":"10.1186\/s13613-020-0642-4_bb0135","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1056\/NEJMra050541","article-title":"Antiinflammatory action of glucocorticoids\u2013new mechanisms for old drugs","volume":"353","author":"Rhen","year":"2005","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1186\/s13613-020-0642-4_bb0140","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1001\/jama.288.7.862","article-title":"Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock","volume":"288","author":"Annane","year":"2002","journal-title":"JAMA"},{"issue":"2","key":"10.1186\/s13613-020-0642-4_bb0145","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJMoa071366","article-title":"Hydrocortisone therapy for patients with septic shock","volume":"358","author":"Sprung","year":"2008","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1186\/s13613-020-0642-4_bb0150","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1056\/NEJMoa1705716","article-title":"Hydrocortisone plus fludrocortisone for adults with septic shock","volume":"378","author":"Annane","year":"2018","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1186\/s13613-020-0642-4_bb0155","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1056\/NEJMoa1705835","article-title":"Adjunctive glucocorticoid therapy in patients with septic shock","volume":"378","author":"Venkatesh","year":"2018","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1186\/s13613-020-0642-4_bb0160","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s00134-011-2409-8","article-title":"Designing and conducting a randomized trial for pandemic critical illness: the 2009 H1N1 influenza pandemic","volume":"38","author":"Annane","year":"2012","journal-title":"Intensive Care Med"},{"issue":"5","key":"10.1186\/s13613-020-0642-4_bb0165","first-page":"271","article-title":"Corticosteroid therapy in critical illness due to seasonal and pandemic influenza","volume":"22","author":"Yale","year":"2015","journal-title":"Can Respir J."}],"container-title":["Annals of Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-020-0642-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s13613-020-0642-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025010635?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025010635?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-020-0642-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T07:38:27Z","timestamp":1776670707000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2110582025010635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020]]}},"alternative-id":["S2110582025010635"],"URL":"https:\/\/doi.org\/10.1186\/s13613-020-0642-4","relation":{},"ISSN":["2110-5820"],"issn-type":[{"value":"2110-5820","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of corticosteroid treatment on clinical outcomes of influenza-associated ARDS: a nationwide multicenter study","name":"articletitle","label":"Article Title"},{"value":"Annals of Intensive Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1186\/s13613-020-0642-4","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2020 The Author(s) 2020. Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}],"article-number":"26"}}