{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:53:13Z","timestamp":1793638393197,"version":"4.5.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"vor","delay-in-days":320,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Intensive Care"],"published-print":{"date-parts":[[2025]]},"DOI":"10.1186\/s13613-025-01488-2","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T12:20:48Z","timestamp":1748866848000},"page":"77","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Critically ill patients with necrotizing soft tissue infections in the Caribbean area: unsupervised analysis of a retrospective cohort (2014\u20132023) with identification of factors associated with mortality"],"prefix":"10.1016","volume":"15","author":[{"given":"Jean-David","family":"Pommier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Tressieres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Blanchet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Desmoulins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Piednoir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nejla","family":"Aissa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Martino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Valette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Demoule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastien","family":"Breurec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0265-429X","authenticated-orcid":false,"given":"Laurent","family":"Camous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1186\/s13613-025-01488-2_bb0010","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1067\/j.cpsurg.2014.06.001","article-title":"Necrotizing soft tissue infections: review and current concepts in treatment, systems of care, and outcomes","volume":"51","author":"Hakkarainen","year":"2014","journal-title":"Curr Probl Surg"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0015","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.cmi.2019.06.031","article-title":"Necrotizing skin and soft-tissue infections in the intensive care unit","volume":"26","author":"Peetermans","year":"2020","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"10.1186\/s13613-025-01488-2_bb0020","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1016\/S1473-3099(22)00583-7","article-title":"Necrotising soft-tissue infections","volume":"23","author":"Hua","year":"2023","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"10.1186\/s13613-025-01488-2_bb0025","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s00134-008-1373-4","article-title":"Influence of surgical treatment timing on mortality from necrotizing soft tissue infections requiring intensive care management","volume":"35","author":"Boyer","year":"2009","journal-title":"Intensive Care Med"},{"issue":"3","key":"10.1186\/s13613-025-01488-2_bb0030","doi-asserted-by":"crossref","first-page":"596","DOI":"10.4269\/ajtmh.21-0009","article-title":"Necrotizing skin and soft tissue infections admitted to intensive care unit in reunion island: a retrospective cohort study","volume":"105","author":"Vandroux","year":"2021","journal-title":"Am J Trop Med Hyg"},{"issue":"6","key":"10.1186\/s13613-025-01488-2_bb0035","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1001\/jamadermatol.2017.0159","article-title":"Clinical characteristics and outcomes of patients with cellulitis requiring intensive care","volume":"153","author":"Cranendonk","year":"2017","journal-title":"JAMA Dermatol"},{"issue":"9","key":"10.1186\/s13613-025-01488-2_bb0040","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1007\/s00134-019-05730-x","article-title":"Patient\u2019s characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study","volume":"45","author":"INFECT Study Group","year":"2019","journal-title":"Intensive Care Med"},{"issue":"2","key":"10.1186\/s13613-025-01488-2_bb0045","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1007\/s00068-021-01706-z","article-title":"Prognostic factors for mortality in 123 severe cases of necrotizing fasciitis in 5 hospitals in the Netherlands between 2003 and 2017","volume":"48","author":"Van Stigt","year":"2022","journal-title":"Eur J Trauma Emerg Surg"},{"issue":"4","key":"10.1186\/s13613-025-01488-2_bb0050","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/SHK.0000000000002325","article-title":"Identification of potentially modifiable factors to improve recognition and outcome of necrotizing soft-tissue infections","volume":"61","author":"Suijker","year":"2024","journal-title":"Shock"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0055","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s13613-022-01087-5","article-title":"Healthcare trajectory of critically ill patients with necrotizing soft tissue infections: a multicenter retrospective cohort study using the clinical data warehouse of Greater Paris University Hospitals","volume":"12","author":"Windsor","year":"2022","journal-title":"Ann Intensive Care"},{"issue":"6","key":"10.1186\/s13613-025-01488-2_bb0060","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.jaad.2015.08.054","article-title":"Prognostic factors in necrotizing soft-tissue infections (NSTI): a cohort study","volume":"73","author":"Hua","year":"2015","journal-title":"J Am Acad Dermatol"},{"issue":"3","key":"10.1186\/s13613-025-01488-2_bb0065","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1177\/08850666211010127","article-title":"Necrotizing soft tissue infections in intensive care","volume":"37","author":"Ogica","year":"2022","journal-title":"J Intensive Care Med"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0070","doi-asserted-by":"crossref","first-page":"38","DOI":"10.4103\/JETS.JETS_17_20","article-title":"Laboratory risk indicator for necrotizing fasciitis score and patient outcomes","volume":"14","author":"Fujinaga","year":"2021","journal-title":"J Emerg Trauma Shock"},{"issue":"5","key":"10.1186\/s13613-025-01488-2_bb0075","first-page":"CD011680","article-title":"Interventions for necrotizing soft tissue infections in adults","volume":"5","author":"Hua","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"10.1186\/s13613-025-01488-2_bb0080","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/jtm.12115","article-title":"Skin and soft tissue infections following marine injuries and exposures in travelers","volume":"21","author":"Diaz","year":"2014","journal-title":"J Travel Med"},{"issue":"10","key":"10.1186\/s13613-025-01488-2_bb0085","doi-asserted-by":"crossref","first-page":"e93","DOI":"10.1086\/497372","article-title":"Skin and soft-tissue infections among tsunami survivors in southern Thailand","volume":"41","author":"Hiransuthikul","year":"2005","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1186\/s13613-025-01488-2_bb0090","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1093\/cid\/ciu296","article-title":"Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America","volume":"59","author":"Stevens","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0095","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s13054-017-1643-z","article-title":"Neuroanatomy of sepsis-associated encephalopathy","volume":"21","author":"Heming","year":"2017","journal-title":"Crit Care"},{"issue":"2","key":"10.1186\/s13613-025-01488-2_bb0100","first-page":"75","article-title":"Neurological complications of sepsis","volume":"29","author":"Piva","year":"2023","journal-title":"Curr Opin Crit Care"},{"key":"10.1186\/s13613-025-01488-2_bb0105","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1056\/NEJMoa1603017","article-title":"Initiation strategies for renal-replacement therapy in the intensive care unit","volume":"375","author":"St\u00e9phane","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1186\/s13613-025-01488-2_bb0110","author":"R Core Team","year":"2023"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v070.i01","article-title":"missMDA: a package for handling missing values in multivariate data analysis","volume":"70","author":"Josse","year":"2016","journal-title":"J Stat Soft"},{"issue":"5","key":"10.1186\/s13613-025-01488-2_bb0120","doi-asserted-by":"crossref","first-page":"469","DOI":"10.15537\/smj.2019.5.24096","article-title":"Effects of seasonal changes in temperature and humidity on incidence of necrotizing soft tissue infections in Halifax, Canada, 2001\u20132015","volume":"40","author":"Fadel","year":"2019","journal-title":"SMJ"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0125","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13017-016-0080-7","article-title":"Review of 58 patients with necrotizing fasciitis in the Netherlands","volume":"11","author":"Van Stigt","year":"2016","journal-title":"World J Emerg Surg"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0130","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1186\/s12879-024-09501-y","article-title":"Association between time to surgery and hospital mortality in patients with community-acquired limb necrotizing fasciitis: an 11-year multicenter retrospective cohort analysis","volume":"24","author":"Lau","year":"2024","journal-title":"BMC Infect Dis"},{"issue":"5","key":"10.1186\/s13613-025-01488-2_bb0135","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1001\/jamasurg.2013.173","article-title":"Immunocompromised status in patients with necrotizing soft-tissue infection","volume":"148","author":"Keung","year":"2013","journal-title":"JAMA Surg"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0140","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1146\/annurev.publhealth.28.021406.144128","article-title":"Seasonality of infectious diseases","volume":"28","author":"Fisman","year":"2007","journal-title":"Annu Rev Public Health"},{"issue":"5","key":"10.1186\/s13613-025-01488-2_bb0145","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1302\/0301-620X.83B5.0830709","article-title":"Necrotising fasciitis of a limb","volume":"83","author":"Tang","year":"2001","journal-title":"J Bone Joint Surg"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0150","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/01.CCM.0000104920.01254.82","article-title":"Rapidly advancing necrotizing fasciitis caused by Photobacterium (Vibrio) damsela: a hyperaggressive variant","volume":"32","author":"Goodell","year":"2004","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1186\/s13613-025-01488-2_bb0155","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.tim.2024.07.009","article-title":"Temperature sensing and virulence regulation in pathogenic bacteria","volume":"33","author":"Roncarati","year":"2024","journal-title":"Trends Microbiol"}],"container-title":["Annals of Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-025-01488-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13613-025-01488-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025000779?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2110582025000779?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13613-025-01488-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T08:09:59Z","timestamp":1776672599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2110582025000779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"alternative-id":["S2110582025000779"],"URL":"https:\/\/doi.org\/10.1186\/s13613-025-01488-2","relation":{},"ISSN":["2110-5820"],"issn-type":[{"value":"2110-5820","type":"print"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Critically ill patients with necrotizing soft tissue infections in the Caribbean area: unsupervised analysis of a retrospective cohort (2014\u20132023) with identification of factors associated with mortality","name":"articletitle","label":"Article Title"},{"value":"Annals of Intensive Care","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1186\/s13613-025-01488-2","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2025 The Author(s) 2025. Published by Elsevier Masson SAS","name":"copyright","label":"Copyright"}],"article-number":"77"}}