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Amacher received grants from the Mach-Gaensslen Foundation Switzerland and the Nora van Meeuwen-Haefliger Foundation of the University of Basel, Switzerland, outside the present work. Gian Marco De Marchis received a speech honoraria from Medtronic. Tolga D. Dittrich was or is supported by the Swiss Heart Foundation, the science funds of the University Hospital Basel, and the Research Fund for excellent young researchers of the University of Basel. He holds shares from Johnson&Johnson, Roche, Lilly, Bristol-Myers Squibb, Merck, and Novo Nordisk. Raoul Sutter received research grants from the Swiss National Foundation (No. 320030_169379), the Research Fund of the University Basel, the Scientific Society Basel, and the Bangerter-Rhyner Foundation. He received personal grants from UCB-pharma and holds stocks from Novartis, Sandoz, Roche, and Johnson & Johnson. 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